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Date:6/3/2010

Nanotechnology-based vaccines 47

Recombinant viral vaccines 48

Synthetic peptides as vaccines 48

Virosomes 49

Vaccines based on reverse genetics 49

Virus-like particles 49

Routine vaccination in children against viral infections 50

Personalized vaccines 50

Limitations of vaccines 50

Neurological complications of vaccination 51

Expert opinion on antiviral vaccines 51

4. Role of Nanotechnology in Developing Antiviral Agents 53

Introduction 53

Study of interaction of nanoparticles with viruses 53

Nanoparticle antiviral agents 54

Fullerenes 54

Nanoviricides 54

Role of micelles in nanopharmaceuticals 55

Some physicochemical characteristics common to polymeric micelles 55

Structure and function of nanoviricides 56

Mechanism of action of NanoViricides 56

Advantages of NanoViricides 57

5. Delivery of Antivirals 59

Introduction 59

Methods of delivery of antiviral agents 59

Local application of antivirals 59

Systemic delivery of protein-polymer antiviral drugs 60

Controlled delivery of antivirals 60

Targeted delivery of antivirals 60

Delivery of antivirals to t
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