Navigation Links
Receptos Scientists Publish Determination of a High Resolution Sphingosine 1-Phosphate Receptor 1 Structure in Science
Date:2/16/2012

SAN DIEGO, Feb. 16, 2012 /PRNewswire/ -- Receptos Inc. announced today the publication of key results relating to its expertise in S1P1 biology and structure-based drug discovery for high-value G-protein-coupled receptor (GPCR) targets in Science.

The article, entitled "Crystal Structure of a Lipid G Protein-Coupled Receptor," was co-authored by Receptos in collaboration with scientific founders Hugh Rosen, M.D., Ph.D., and Raymond Stevens, Ph.D. Drs. Rosen and Stevens are both professors at The Scripps Research Institute®, with expertise in immunology and lymphocyte trafficking and GPCR crystallography, respectively. Receptos is the exclusive licensee of the GPCR crystal structure determination technology platform, developed at The Scripps Research Institute®, which enabled the elucidation of the S1P1 receptor structure.

"Receptos and its founders have an unparalleled track record in the determination of high resolution GPCR structures to enable rational drug design," said Faheem Hasnain, President and Chief Executive Officer of Receptos. "The publication of the S1P1 structure in Science highlights the importance of this therapeutic target and Receptos's leading position in decoding receptor-ligand interactions for pharmaceutically relevant GPCR targets. Our expertise in the S1P1 field has resulted in the discovery of a best-in-class small molecule agonist, RPC1063, which is scheduled to initiate Phase 2 clinical studies in multiple sclerosis and inflammatory bowel disease later this year."

Receptos utilizes the GPCR crystal structure determination technology platform to assist in building a pipeline of high-value therapeutic candidates. In addition to RPC1063, the technology supports a small molecule glucagon-like peptide 1 (GLP1) research program, which has demonstrated proof of concept in in vivo models of type 2 diabetes. Receptos has also initiated technology collaborations to c
'/>"/>

SOURCE Receptos
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Receptos and Ono Establish Collaboration with Focus on Bioactive Lipid Discovery Research
2. Scientists decode brain waves to eavesdrop on what we hear
3. Chinese Scientists Zhen-Yi Wang and Zhu Chen Awarded 7th Annual Szent-Gyorgyi Prize for Progress in Cancer Research
4. iBioSeminars and iBioMagazine: Free, Online Biology Seminars and Short Talks by Leading Scientists
5. Scientists solve mystery of colorful armchair nanotubes
6. Nanowiggles: Scientists discover graphene nanomaterials with tunable functionality in electronics
7. Sheffield scientists shine a light on the detection of bacterial infection
8. Singapore scientists lead human embryonic stem cell study
9. Scientists defuse the Vietnam time bomb
10. Scientists carve nanowires out of ultrananocrystalline diamond thin films
11. Berkeley Lab scientists develop new tool for the study of spatial patterns in living cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... MO (PRWEB) July 28, 2014 ... and services that bring the power of genomics to ... inaugural Appistry Pipeline Challenge . , Two ... president of the National Center for Genome Resources, and ... Hospitals and Clinics of Kansas City. Rounding out the ...
(Date:7/28/2014)...  InterMune, Inc. (NASDAQ: ITMN ) today ... financial results at the close of the U.S. markets ... webcast will be hosted by InterMune at 4:30 p.m. ... and others may participate in the conference call by ... replay of the webcast and teleconference will be available ...
(Date:7/28/2014)... The National Model Aviation Museum, located ... pleased to announce that it has been granted full ... United States Air Force. , The certification is the ... this spring with an on-site inspection by Sarah Sessions, ... The National Museum of the United States Air ...
(Date:7/25/2014)... Amgen (NASDAQ: AMGN ) announced ... per share dividend for the third quarter of 2014. ... to all stockholders of record as of the close ... About Amgen Amgen is committed to unlocking the potential ... discovering, developing, manufacturing and delivering innovative human therapeutics. This ...
Breaking Biology Technology:Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2InterMune to Release Second Quarter Financial Results on August 6 2AMA’s National Model Aviation Museum Granted Full Civilian Museum Certification by the National Museum of the United States Air Force 2Amgen Announces 2014 Third Quarter Dividend 2Amgen Announces 2014 Third Quarter Dividend 3
(Date:7/25/2014)... A study published online in the International ... novel approach to preventing cervical cancer based on findings ... after removal of a discrete population of cells in ... study that looked at squamocolumnar junction cells, or SCJ ... have been implicated as the origins of cervical cancer. ...
(Date:7/25/2014)... characterized by the existence of numerous isoforms arising ... the protein deeply different characteristics. NRG1 plays an ... development and the different phases occurring after injury ... remyelination and target reinnervation, Researchers at the University ... NRG1 upregulation observed in Schwann cells immediately after ...
(Date:7/25/2014)... of a molecular testing panel developed at UPMC ... initial surgery for patients with thyroid nodules and ... Cancer Institute (UPCI), partner with UPMC CancerCenter., The ... and other diagnostic testing agencies, improved the chances ... 30 percent, according to the study published this ...
Breaking Biology News(10 mins):Clearing cells to prevent cervical cancer 2Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3
... of genetic regions known to be implicated in Crohn,s disease, ... research, published today in the journal Nature Genetics , ... development as well as providing surprising new links between the ... disease affects between 1 in 500 and 1 in 1000 ...
... choosing mates. Flowering plant pollination systems are clever ... there are also mechanisms for keeping out unwanted pollen. ... reject such pollen because of the deleterious effects of inbreeding. ... close relatives is rejected if it lands on the female ...
... Two Montana state University researchers are principal editors on ... ways to study carnivores in the wild. "Noninvasive ... June 27 with Robert Long and Paula MacKay as ... Western Transportation Institute. Working with two co-editors ...
Cached Biology News:Complexity of Crohn's disease revealed as 'gene' count tops 30 2Complexity of Crohn's disease revealed as 'gene' count tops 30 3Mate choice in plants 2Mate choice in plants 3
Proteinase K Buffer 3.9 ml...
Rabbit polyclonal to hCG ( Abpromise for all tested applications). entrezGeneID: 1081 SwissProtID: P01215...
Anti-Indolamine (Indoleamine) 2,3-dioxygenase Immunogen: Recombinant human IDO. Available Date: 38454...
Glutathione Agarose Beads 10 ml...
Biology Products: