Navigation Links
Receptos Scientists Publish Determination of a High Resolution Sphingosine 1-Phosphate Receptor 1 Structure in Science
Date:2/16/2012

SAN DIEGO, Feb. 16, 2012 /PRNewswire/ -- Receptos Inc. announced today the publication of key results relating to its expertise in S1P1 biology and structure-based drug discovery for high-value G-protein-coupled receptor (GPCR) targets in Science.

The article, entitled "Crystal Structure of a Lipid G Protein-Coupled Receptor," was co-authored by Receptos in collaboration with scientific founders Hugh Rosen, M.D., Ph.D., and Raymond Stevens, Ph.D. Drs. Rosen and Stevens are both professors at The Scripps Research Institute®, with expertise in immunology and lymphocyte trafficking and GPCR crystallography, respectively. Receptos is the exclusive licensee of the GPCR crystal structure determination technology platform, developed at The Scripps Research Institute®, which enabled the elucidation of the S1P1 receptor structure.

"Receptos and its founders have an unparalleled track record in the determination of high resolution GPCR structures to enable rational drug design," said Faheem Hasnain, President and Chief Executive Officer of Receptos. "The publication of the S1P1 structure in Science highlights the importance of this therapeutic target and Receptos's leading position in decoding receptor-ligand interactions for pharmaceutically relevant GPCR targets. Our expertise in the S1P1 field has resulted in the discovery of a best-in-class small molecule agonist, RPC1063, which is scheduled to initiate Phase 2 clinical studies in multiple sclerosis and inflammatory bowel disease later this year."

Receptos utilizes the GPCR crystal structure determination technology platform to assist in building a pipeline of high-value therapeutic candidates. In addition to RPC1063, the technology supports a small molecule glucagon-like peptide 1 (GLP1) research program, which has demonstrated proof of concept in in vivo models of type 2 diabetes. Receptos has also initiated technology collaborations to c
'/>"/>

SOURCE Receptos
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Receptos and Ono Establish Collaboration with Focus on Bioactive Lipid Discovery Research
2. Scientists decode brain waves to eavesdrop on what we hear
3. Chinese Scientists Zhen-Yi Wang and Zhu Chen Awarded 7th Annual Szent-Gyorgyi Prize for Progress in Cancer Research
4. iBioSeminars and iBioMagazine: Free, Online Biology Seminars and Short Talks by Leading Scientists
5. Scientists solve mystery of colorful armchair nanotubes
6. Nanowiggles: Scientists discover graphene nanomaterials with tunable functionality in electronics
7. Sheffield scientists shine a light on the detection of bacterial infection
8. Singapore scientists lead human embryonic stem cell study
9. Scientists defuse the Vietnam time bomb
10. Scientists carve nanowires out of ultrananocrystalline diamond thin films
11. Berkeley Lab scientists develop new tool for the study of spatial patterns in living cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/14/2014)... when it comes to survival strategies. They often create ... for example during treatment with antibiotics. A biofilm is ... slime capsule consisting of sugar chains and "curli". ... the first time created a detailed three-dimensional image of ... the bacterial cell wall, a crucial step in the ...
(Date:9/12/2014)... magnet using an electric field (magnetoelectric memory [MEM] ... next-generation technology for information processing and storage. Multiferroic ... due to the coexistence of electric and magnetic ... spontaneous electric and magnetic polarizations is rare in ... the MEM effect. This article briefly reviews a ...
(Date:9/12/2014)... Advancing the front lines of ... and biological threats is the mission of an ... (WPI) and the Georgian National Academy of Sciences, ... and Security Programme of the North Atlantic Treaty ... Workshop series, the event is titled “Nanotechnology to ...
(Date:9/12/2014)... Mountain View, CA (PRWEB) September 12, 2014 ... its fundraising campaign on Indiegogo. , The film, ... Stephen Hawking, Buzz Aldrin, Shimon Peres, Ashton Kutcher, Will.i.Am, ... changing the world and there’s only one university in ... it to help change the lives of a billion ...
Breaking Biology Technology:New insights in survival strategies of bacteria 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2
... , , , , , , ... Amex: NBS ) ("NeoStem" or the "Company"), an international,biopharmaceutical company ... it priced a public offering of 5,000,000 shares of its common ... after underwriting,discounts and commissions and expenses, will be approximately $5,697,500 ...
... , , , SHENYANG, ... Inc. (Nasdaq:, SSRX ) ("3SBio" or "the Company"), a ... manufacturing and marketing,biopharmaceutical products, and Ascentage Pharma Group Corporation, ... strategic,alliance to research, develop and commercialize best-in-class targeted cancer,therapeutics ...
... simple one-step process that produces both n-type and ... use of the promising material for future electronic ... used to increase conductivity in graphene nanoribbons used ... (SOG) material to graphene and then exposing it ...
Cached Biology Technology:NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 2NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 3NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 43SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 23SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 33SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 4Single-step technique produces both p-type and n-type doping for future graphene devices 2Single-step technique produces both p-type and n-type doping for future graphene devices 3
(Date:9/15/2014)... the Department of Science and Technology in Society in ... Virginia Tech, has won a 2014 National Science Foundation ... and problems of creating a global nuclear emergency response ... Nuclear Power Plant in March 2011 was a turning ... Schmid said. Three of the plant,s six nuclear reactors ...
(Date:9/15/2014)... of the cheetah: The big predator is the fastest land ... just a few seconds. As it ramps up to top ... it reaches a full gallop. , Now MIT researchers have ... a robotic cheetah a sleek, four-legged assemblage of gears, ... its feline counterpart. The team recently took the robot for ...
(Date:9/15/2014)... no published account where hippopotamuses are demonstrably shown swimming ... water. But if they can,t swim, how did they ... accepted models for the methods, patterns, and timing of ... Crete, and Madagascar) may need to be reconsidered. , ... mainland are not currently supported by positive geological ...
Breaking Biology News(10 mins):'Nuclear disasters don't respect national boundaries' 2Run, cheetah, run 2Run, cheetah, run 3
... shift away from traditional coffee-growing techniques may be increasing ... that has swept through plantations in Central America and ... studies the disease. The current outbreak of coffee ... Mexico since the fungal disease arrived in the region ...
... stations could be drastically reduced by a new, energy-efficient ... releases it when exposed to sunlight. In a ... University and CSIRO scientists for the first time discovered ... of materials known for their exceptional capacity to store ...
... African-American women battling vitamin D deficiencies need the same ... to a recent study accepted for publication in The ... (JCEM). Although women with darker skin tones ... to measure Vitamin D levels, called 25-hydroxyvitamin D or ...
Cached Biology News:Modern growing methods may be culprit of 'coffee rust' fungal outbreak 2Modern growing methods may be culprit of 'coffee rust' fungal outbreak 3Carbon sponge could soak up coal emissions 2African-American, Caucasian women should take identical vitamin D doses 2