Navigation Links
Plague researchers race to beat bioterrorists
Date:10/4/2010

nation of a plague "bio-bomb" over a city of five million could cause 150,000 cases of pneumonic plague, leading to 36,000 fatalities.

Small, natural outbreaks of plague continue to this day, and it remains among the deadliest of infectious diseases. Yet there continues to be no effective and reliable vaccine against the disease.

Both the United States and the United Kingdom are funding research aimed at developing an antibody-based vaccine against plague. Why antibodies? Antibodies are special proteins produced by the immune system in response to foreign invaders like bacteria, viruses and other microbes. After the immune system utilizes an antibody to fight off a dangerous pathogen, it retains a "memory" of the invader, so the relevant antibody can be rapidly reproduced should it encounter that same pathogen in the future. Many vaccines work by simulating exposure to a pathogen, thereby training the body to quickly generate the appropriate antibodies.

Several years ago, however, an enigma arose when the U.S. Army tested the leading plague vaccine candidate in two types of primates. Both produced similar amounts of antibody, but vaccination protected one type of animal much better than the other. Unfortunately, it's not clear whether humans are more like the primates that were, or were not, protected. Most likely, humans will exhibit a range of responses, some similar to the one type of primate and some closer to the other.

In the current issue of the journal Vaccine, Dr. Smiley's research group publishes data that may help unravel this enigma and provide a way to predict who will be protected with the plague vaccine being developed by the Army. In collaboration with the U.S. and U.K. militaries, as well as the Northeast Biodefense Center, they have shown that antibodies receive help from another part of the immune system when they protect against plague. Dr. Smiley's laboratory has focused its efforts on pneumonic plag
'/>"/>

Contact: Brian Turner
bturner@trudeauinstitute.org
518-891-3080
Trudeau Institute
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. New Weapon in BioDefense Research: NanoLogix Kit Speeds Rapid Diagnostics of Anthrax and Bubonic Plague
2. UCF professor develops vaccine to protect against black plague bioterror attack
3. UCF professor develops vaccine to protect against black plague bioterror attack
4. Researchers sequence genome of mosquito that spreads West Nile virus
5. Elsevier Survey Reveals Researchers Ready to Push Scientific Search and Discovery to the Next Level
6. Researchers discover less expensive low-temperature catalyst for hydrogen purification
7. Researchers expand yeasts sugary diet to include plant fiber
8. NIST researchers hear puzzling new physics from graphene quartets quantum harmonies
9. Virginia Tech researchers contribute to turkey genome sequencing
10. Researchers create new class of piezoelectric logic devices using zinc oxide nanowires
11. Researchers stretch a lackluster material into a possible electronics revolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plague researchers race to beat bioterrorists
(Date:1/22/2015)... Eckert & Ziegler Vitalea Science (EZVS), a leading ... pharmaceutical and biotech industry, has announced that Dr. Mark ... of Director of Science & Technology. , “Mark brings ... drug metabolism and bioanalysis to EZVS in both pharma ...
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... Jan. 22, 2015  Transwestern | RBJ today announces the firm ... space for Shire a leading biopharmaceutical company, at Two Ledgemont ... RBJ,s Robert Richards , president, and Brian Cohen ... the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... 2015 The laboratory information management systems ... a number of technological advancements due to factors such ... need to integrate healthcare systems, and increasing government support ... system integration. Key players in the market focus on ...
Breaking Biology Technology:Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 2Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 3Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4
... - Live Webcast -- LONDON, October 29, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... var s = ,; var first_result; // Results are keyed by longUrl, so we need to grab the first ...
... Oct. 28 Orexigen® Therapeutics, Inc. (Nasdaq: OREX ... today announced that on October 26, 2010 the Compensation Committee ... an inducement stock option to purchase 9,000 shares of common ... has an exercise price per share equal to $5.79, the ...
... ANNAPOLIS, Md., Oct. 28 PharmAthene, Inc. (NYSE Amex: ... biological and chemical threats, today announced that it intends to ... underwritten public offering. The offering is subject to market conditions ... when the offering may be completed, or as to the ...
Cached Biology Technology:Hikma Expands its Global Injectables Business - Live Webcast 2Hikma Expands its Global Injectables Business - Live Webcast 3Hikma Expands its Global Injectables Business - Live Webcast 4Hikma Expands its Global Injectables Business - Live Webcast 5Hikma Expands its Global Injectables Business - Live Webcast 6Hikma Expands its Global Injectables Business - Live Webcast 7Orexigen(R) Therapeutics Reports Inducement Grant Under NASDAQ Listing Rule 5635(c)(4) 2PharmAthene Announces Proposed Common Stock Offering 2PharmAthene Announces Proposed Common Stock Offering 3
(Date:1/22/2015)... NEW YORK , Jan. 22, 2015   EyeLock, Inc. ... announced it has appointed Steve Gerber to the ... Gerber will be responsible for leading development of mobile platforms ... 25 years of success and innovation in the semiconductor industry ...
(Date:12/22/2014)... DUBLIN , Dec. 22, 2014 Research and ... the addition of the "The Global Watermarking ... http://photos.prnewswire.com/prnh/20130307/600769 ... global digital media watermarking and fingerprinting markets. Watermarking ...
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal genetics company, ... differences in genetic ancestry of individuals from across ... arrived more than four hundred years ago, the ... for peoples from different continents. This study illuminates how American ...
Breaking Biology News(10 mins):EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2The Global Watermarking and Fingerprinting Markets 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4
... Research teams at Yale University and the University of Rhode ... treat tumors using a short piece of protein that acts ... to a report in the Proceedings of the National Academy ... called “pHLIP?(pH (Low) Insertion Peptide) can be injected into the ...
... on islands around the world has confirmed what island ... islands are much more abundant than their counterparts on ... study signals an alarm for island populations in a ... have devastating consequences for lizards and other animals that ...
... have converted protein sequences into classical music in an ... of genomic biology. New research published today in the ... found a way to present human proteins as musical ... the University of California, Los Angeles, USA, have so ...
Cached Biology News:pHLIP, a novel technology to locate and treat tumors 2Global survey of lizards reveals greater abundance of animals on islands than on mainland ecosystems 2Global survey of lizards reveals greater abundance of animals on islands than on mainland ecosystems 3The sound of proteins 2