Navigation Links
Plague researchers race to beat bioterrorists
Date:10/4/2010

nation of a plague "bio-bomb" over a city of five million could cause 150,000 cases of pneumonic plague, leading to 36,000 fatalities.

Small, natural outbreaks of plague continue to this day, and it remains among the deadliest of infectious diseases. Yet there continues to be no effective and reliable vaccine against the disease.

Both the United States and the United Kingdom are funding research aimed at developing an antibody-based vaccine against plague. Why antibodies? Antibodies are special proteins produced by the immune system in response to foreign invaders like bacteria, viruses and other microbes. After the immune system utilizes an antibody to fight off a dangerous pathogen, it retains a "memory" of the invader, so the relevant antibody can be rapidly reproduced should it encounter that same pathogen in the future. Many vaccines work by simulating exposure to a pathogen, thereby training the body to quickly generate the appropriate antibodies.

Several years ago, however, an enigma arose when the U.S. Army tested the leading plague vaccine candidate in two types of primates. Both produced similar amounts of antibody, but vaccination protected one type of animal much better than the other. Unfortunately, it's not clear whether humans are more like the primates that were, or were not, protected. Most likely, humans will exhibit a range of responses, some similar to the one type of primate and some closer to the other.

In the current issue of the journal Vaccine, Dr. Smiley's research group publishes data that may help unravel this enigma and provide a way to predict who will be protected with the plague vaccine being developed by the Army. In collaboration with the U.S. and U.K. militaries, as well as the Northeast Biodefense Center, they have shown that antibodies receive help from another part of the immune system when they protect against plague. Dr. Smiley's laboratory has focused its efforts on pneumonic plag
'/>"/>

Contact: Brian Turner
bturner@trudeauinstitute.org
518-891-3080
Trudeau Institute
Source:Eurekalert  

0

GOOD

Page: 1 2 3

Related biology technology :

1. New Weapon in BioDefense Research: NanoLogix Kit Speeds Rapid Diagnostics of Anthrax and Bubonic Plague
2. UCF professor develops vaccine to protect against black plague bioterror attack
3. UCF professor develops vaccine to protect against black plague bioterror attack
4. Researchers sequence genome of mosquito that spreads West Nile virus
5. Elsevier Survey Reveals Researchers Ready to Push Scientific Search and Discovery to the Next Level
6. Researchers discover less expensive low-temperature catalyst for hydrogen purification
7. Researchers expand yeasts sugary diet to include plant fiber
8. NIST researchers hear puzzling new physics from graphene quartets quantum harmonies
9. Virginia Tech researchers contribute to turkey genome sequencing
10. Researchers create new class of piezoelectric logic devices using zinc oxide nanowires
11. Researchers stretch a lackluster material into a possible electronics revolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plague researchers race to beat bioterrorists
(Date:5/21/2013)... PALM BEACH, Fla. , May 21, 2013 ... (NYSE: FCN ), the global business ... enhance their enterprise value (the "Company"), announced that ... focused personnel that were formerly included within the ... and Litigation Consulting segment to form a single ...
(Date:5/21/2013)... YORK , May 21, 2013  The Lindsley F. ... today that it is a Grand Challenges Explorations ... Gates Foundation .  Dr. Sara Lustigman , ... innovative global health and development research project, titled Innovative ...  These worms are needed to screen drugs to help ...
(Date:5/21/2013)... May 21, 2013 Custom Learning ... reporting eLearning solution using Tin Can API combined ... tool. CLD is a leading developer of training ... device companies worldwide. , Tin Can API ... helps learners and trainers more accurately measure the ...
(Date:5/21/2013)... Bellingham, WA (PRWEB) May 21, 2013 ... teacher trainings, and funds for lab equipment, 25 organizations ... relevance and importance of optics and photonics in daily ... Grants . , The organizations, located in 10 countries, ... grants to be awarded by SPIE, the international ...
Breaking Biology Technology:FTI Consulting Releases Realigned Segment Information Reflecting Newly Combined Health Solutions Practice 2New York Blood Center's Research Institute Receives Grand Challenges Explorations Grant For Groundbreaking Research in Global Health and Development 2New York Blood Center's Research Institute Receives Grand Challenges Explorations Grant For Groundbreaking Research in Global Health and Development 3CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 2CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 3Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 2Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 3
... For Metal Products and Surfaces Prompts Horizon Business Group To ... ... New Company, NORTHBROOK, Ill., Oct. 29 Due to ... easy-to-clean characteristics to enhance the,performance, aesthetics and durability of metal ...
... Oct. 29 Cliniqa Corporation (San,Marcos, CA), ... pleased to,announce the acquisition of the primary ... CA), a wholly owned subsidiary of Hemagen,Diagnostics, ... of clinical,diagnostic products focusing on clinical chemistry ...
... secret of buckyballs -- hollow spheres of carbon no ... caught on tape by researchers at Sandia National Laboratory ... simulations show that "shrink-wrapping" is the key; buckyballs start ... connected threads and chains until only the perfectly spherical ...
Cached Biology Technology:Sureshield Coatings Company Established to Market Industry-Leading Portfolio of Advanced Coatings for Metal Surfaces 2Sureshield Coatings Company Established to Market Industry-Leading Portfolio of Advanced Coatings for Metal Surfaces 3Cliniqa Corporation Completes Asset Acquisition of Reagents Applications, Inc. 2Video shows buckyballs form by 'shrink wrapping' 2
(Date:5/21/2013)... Biologists have known for a long time that some ... well understood, particularly for plants. But it may be ... Australian National University and the U. S. National Evolutionary ... published 21 May in the journal Nature Communications ... faster-changing genomes. , Drawing from a database of global ...
(Date:5/21/2013)... to a whale entangled in fishing gear, scientists showed ... whale,s diving and swimming behavior. The monitoring revealed how ... depletes their energy as they drag gear for months ... , The scientists in this entanglement response suction-cupped a ... North Atlantic right whale called Eg 3911. The Dtag, ...
(Date:5/21/2013)... being considered in the management of natural resources, ... can help them recognize and respond to the ... lives. , Place-Based Conservation: Perspectives from the ... Pacific Northwest Research Station,s Linda Kruger, can help ... book is published by Springer Verlag and is ...
Breaking Biology News(10 mins):Small but speedy: Short plants live in the evolutionary fast lane 2Study reveals how fishing gear can cause slow death of whales 2Study reveals how fishing gear can cause slow death of whales 3
... 50,000 people have uncovered several DNA sequence variations associated ... The findings, reported in Nature Genetics , may ... mechanisms for abnormal heart rhythms and sudden cardiac death. ... complex," says co-author Glenn I. Fishman, MD, the William ...
... OTTAWA November 14, 2010 One of the ... the University of Ottawa Heart Institute (UOHI), conclusively proves that ... beat while reducing risk of death by 24% compared to ... Tang and Dr. George Wells at the Heart Institute, brings ...
... Health intramural researcher Mortimer Mishkin, Ph.D., will be awarded ... ceremony later this month. Mishkin is chief of ... Cognitive Neuroscience, and acting chief of its Laboratory of ... to receive the medal, which the President presents each ...
Cached Biology News:DNA sequence variations linked to electrical signal conduction in the heart 2Synchronizing a failing heart 2NIMH's Dr. Mortimer Mishkin to be awarded National Medal of Science 2NIMH's Dr. Mortimer Mishkin to be awarded National Medal of Science 3
Prostaglandin E2 Luminex Standard Product Lines: Unspecified...
Rabbit polyclonal to HMGB1 (rating: ****) ( Abpromise for all tested applications). entrezGeneID: 3146 SwissProtID: P09429...
Eppendorf tube holder, for Tube rack 175 x 12 mm, 100. Category: Chromatography Systems & Accessories, Systems....
ERalpha (Ser 104/106)...
Biology Products: