Navigation Links
Plague researchers race to beat bioterrorists
Date:10/4/2010

nation of a plague "bio-bomb" over a city of five million could cause 150,000 cases of pneumonic plague, leading to 36,000 fatalities.

Small, natural outbreaks of plague continue to this day, and it remains among the deadliest of infectious diseases. Yet there continues to be no effective and reliable vaccine against the disease.

Both the United States and the United Kingdom are funding research aimed at developing an antibody-based vaccine against plague. Why antibodies? Antibodies are special proteins produced by the immune system in response to foreign invaders like bacteria, viruses and other microbes. After the immune system utilizes an antibody to fight off a dangerous pathogen, it retains a "memory" of the invader, so the relevant antibody can be rapidly reproduced should it encounter that same pathogen in the future. Many vaccines work by simulating exposure to a pathogen, thereby training the body to quickly generate the appropriate antibodies.

Several years ago, however, an enigma arose when the U.S. Army tested the leading plague vaccine candidate in two types of primates. Both produced similar amounts of antibody, but vaccination protected one type of animal much better than the other. Unfortunately, it's not clear whether humans are more like the primates that were, or were not, protected. Most likely, humans will exhibit a range of responses, some similar to the one type of primate and some closer to the other.

In the current issue of the journal Vaccine, Dr. Smiley's research group publishes data that may help unravel this enigma and provide a way to predict who will be protected with the plague vaccine being developed by the Army. In collaboration with the U.S. and U.K. militaries, as well as the Northeast Biodefense Center, they have shown that antibodies receive help from another part of the immune system when they protect against plague. Dr. Smiley's laboratory has focused its efforts on pneumonic plag
'/>"/>

Contact: Brian Turner
bturner@trudeauinstitute.org
518-891-3080
Trudeau Institute
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. New Weapon in BioDefense Research: NanoLogix Kit Speeds Rapid Diagnostics of Anthrax and Bubonic Plague
2. UCF professor develops vaccine to protect against black plague bioterror attack
3. UCF professor develops vaccine to protect against black plague bioterror attack
4. Researchers sequence genome of mosquito that spreads West Nile virus
5. Elsevier Survey Reveals Researchers Ready to Push Scientific Search and Discovery to the Next Level
6. Researchers discover less expensive low-temperature catalyst for hydrogen purification
7. Researchers expand yeasts sugary diet to include plant fiber
8. NIST researchers hear puzzling new physics from graphene quartets quantum harmonies
9. Virginia Tech researchers contribute to turkey genome sequencing
10. Researchers create new class of piezoelectric logic devices using zinc oxide nanowires
11. Researchers stretch a lackluster material into a possible electronics revolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Plague researchers race to beat bioterrorists
(Date:10/31/2014)... Fla. , Oct. 31, 2014  Tavistock ... owned by Tavistock Group, celebrated the groundbreaking of the ... Medical City. The 92,000-square-foot, three-story ... Central Florida designed specifically for ... in the heart of the 650-acre Lake Nona ...
(Date:10/30/2014)... Global polyvinyl chloride (PVC) demand registered a significant ... especially in North America and Europe. However, the global ... a growing trend. , The largest chunk of the ... segment. In 2013, the key PVC application spheres included ... film. Moreover, the PVC was consumed in the production ...
(Date:10/30/2014)... James Sherley says he has been working ... cell technology since his days as a principal investigator at ... late 1990’s. Sherley founded the ASCTC as a new ... the intellectual property developed in Sherley’s research over the years ... of Technology (MIT), and more recently as a senior scientist ...
(Date:10/30/2014)... Isis Pharmaceuticals, Inc. (NASDAQ: ISIS ), ... present a company overview at the Nomura Biotechnology Conference on ... Boston, MA. A live webcast ... Media" section of the Company,s website, www.isispharm.com .  A ... hours and will be archived for a limited time. ...
Breaking Biology Technology:GuideWell Innovation Center Groundbreaking Hosted by Tavistock Development Company at Lake Nona Medical City 2GuideWell Innovation Center Groundbreaking Hosted by Tavistock Development Company at Lake Nona Medical City 3Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 2Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 3Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 2Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 3Boston’s Adult Stem Cell Technology Center, LLC Introduces A New Technology for Monitoring Previously Elusive Adult Stem Cells 4Isis Pharmaceuticals to Present at the Nomura Biotechnology Conference 2
... Corporation,(OTC Bulletin Board: CONX), a worldwide developer and ... Test at the,American Diabetes Association,s 68th Scientific Sessions. ... - 9, 2008, at the Moscone Convention,Center in ... time the AspirinWorks test will be exhibited at,the ...
... Ongoing Live-Cell Research, MELVILLE, N.Y., June ... and Northwestern University,s Feinberg School of,Medicine announced ... imaging,center, establishing a partnership that brings improved ... for Nikon,product development. One of only three ...
... Therapeutics, a drug,and diagnostic company, today announces that ... 1st as Chief Operating Officer. At the next,meeting ... CEO (President du,Directoire)., Laurent Condomine, Chairman of ... Loic Maurel joining ExonHit Therapeutics. His,experience and track ...
Cached Biology Technology:Corgenix to Exhibit AspirinWorks(R) Test at ADA 2008 Meeting in San Francisco 2Corgenix to Exhibit AspirinWorks(R) Test at ADA 2008 Meeting in San Francisco 3Nikon Instruments Opens New Imaging Center at Northwestern University 2Nikon Instruments Opens New Imaging Center at Northwestern University 3Loic Maurel Joins Exonhit Therapeutics to Become CEO 2Loic Maurel Joins Exonhit Therapeutics to Become CEO 3Loic Maurel Joins Exonhit Therapeutics to Become CEO 4
(Date:10/29/2014)... Researching the safety of nanoparticles is all the rage. ... topic, examining the question of whether titanium dioxide nanoparticles ... into the body, whether carbon nanotubes from electronic products ... to be or whether nanoparticles in food can get ... Public interest is great, research funds are flowing – ...
(Date:10/29/2014)... decompose, their types and numbers of bugs and ... mean the difference between a closed case and ... using a more than $866,000 U.S. Department of ... these changing populations. The microbial communities may provide ... gender, race, socioeconomic relations and more, said Eric ...
(Date:10/29/2014)... of stem cell, those referred to as ,facultative, form ... apparently nothing that differentiates these cells from the others. ... retain the capacity to become stem cells again. This ... organ that hosts cells that stimulate tissue growth, thus ... of a transplant. Knowledge of the underlying mechanism ...
Breaking Biology News(10 mins):Nanosafety research: The quest for the gold standard 2Nanosafety research: The quest for the gold standard 3MSU partners with Detroit to investigate death scenes 2A mechanism that allows a differentiated cell to reactivate as a stem cell revealed 2
... new study of transfer RNA, a molecule that delivers amino ... ideas about the evolutionary history of protein synthesis., In the ... (reading the genetic blueprint for a protein, and adding a ... appear to have originated independently of one another. The new ...
... a devastating new wheat disease strain which could lead to ... in the United States, with funding from the Bill & ... undertake the research as part of the Durable Rust Resistance ... the fungus, wheat stem rust. World leaders in rust ...
... has been honored for his role in the development ... who suffer severe, life-threatening injuries in Iraq and Afghanistan. ... for Combat Casualty Care Award was presented to Stucky ... annual meeting in Florida. The ATACCC convention is the ...
Cached Biology News:Study reveals surprising details of the evolution of protein translation 2CSIRO enlisted to avert global wheat supply crisis 2UCSB chemistry professor receives top military award for life-saving gauze 2UCSB chemistry professor receives top military award for life-saving gauze 3
The filter 605DF50 for the Molecular Imager FX is a band pass filter for ethidium bromide, SYPRO Red, SYPRO Ruby, Alexa Fluor 532 and 546, and Cy3 dyes when using the 635 nm laser....
The sample holders for gels are used to hold gels in place in the multi-sample tray I, which is used with Molecular Imager FX imaging systems....
... APO-DIRECT is a single-step staining method ... cells by flow cytometry. The kit contains ... apoptosis in cells including: positive and negative ... reaction and rinsing buffers for processing individual ...
... is specifically for electrofocusing. It ... is recommended for electrofocusing of ... or complexes that are subject ... sieving in polyacrylamide gels. Supplied ...
Biology Products: