Navigation Links
On quills and needles: Prickly porcupine is a muse for future medical devices
Date:12/10/2012

BOSTON, MAResearchers from Brigham and Women's Hospital (BWH) have uncovered how North American porcupine quills easily penetrate tissues and why, once lodged in flesh, they are often difficult to remove.

The researchers, led by Jeffrey Karp, PhD, BWH Division of Biomedical Engineering, Department of Medicine, senior study author, along with Robert Langer, Ph.D from Massachusetts Institute of Technology (MIT), state that the discovery could prompt device makers to design medical needles that easily penetrate surfaces and resist buckling, as well as create next-generation medical adhesives.

The study will be published online on December 10, 2012 in Proceedings of the National Academy of Sciences.

The scientists used natural porcupine quills and replica-molded synthetic polyurethane quills to understand the physical forces at play when the quills penetrate and are removed from a variety of tissues, including muscle and skin.

The North American porcupine has approximately 30,000 defensive quills on its back. The porcupine releases its quills upon contact with predators. Each quill contains a conical black tip studded with a layer of microscopic, backward-facing barbs and a cylindrical base with smooth, scale-like structures.

The researchers revealed that the quill's geometry enables it to penetrate tissue with ease, and once in the tissue it maintains high adhesion.

"The philosopher Aristotle who was clearly misinformed warned that porcupines could shoot their quills over great distances, which is completely untrue," said Karp. "In fact there are many misconceptions about porcupines and their quills. We were most surprised to find that the barbs on quills serve a dual function. Namely, the barbs reduce the penetration force for easy insertion into tissue and maximize the holding force to make the quills incredibly difficult to remove."

According to the researchers, since quills do not shoo
'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Inspiration from a porcupines quills
2. New 4-D transistor is preview of future computers
3. Bioprinting has promising future
4. SAHYOG: Future of Bio-based Economy in India and European Union
5. New study reveals challenge facing designers of future computer chips
6. New discovery shows promise in future speed of synthesizing high-demand nanomaterials
7. ViThera Novel Approach Using Probiotics to Deliver Elafin Shows Promise as a Future Inflammatory Bowel Disease (IBD) Treatment
8. Epigenetics Holds Key to Healthier Future
9. Electronics without current: Finnish team to research the future of nanoelectronics
10. Epigenomics, Present and Future Applications for Pharmaceuticals and Diagnostics: Twease.org
11. Future memory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
On quills and needles: Prickly porcupine is a muse for future medical devices
(Date:10/25/2014)... NEW YORK , Oct. 24, ... formerly Access Pharmaceuticals, Inc. (ACCP), a biopharmaceutical company ... has implemented a 1-for-50 reverse split of its ... on Friday, October 24, 2014. PlasmaTech,s common stock ... CUSIP number 72754H109 and temporary ticker symbol "ACCPD". ...
(Date:10/22/2014)... , Oct. 22, 2014 New test innovations ... in vitro diagnostic (IVD) test industry, especially as companies ... market researcher listed more than 25 testing innovations in ... the future of IVD products. Kalorama details the new approaches ... Worldwide Market for In Vitro Diagnostic Tests , ...
(Date:10/22/2014)... Md. (PRWEB) October 21, 2014 Shimadzu ... an LC/MS/MS data tool for the pain management and ... of data processing and review by allowing users to ... to clinicians. , QuantAnalytics allows analysts to filter ... This expedites data processing by eliminating the need to ...
(Date:10/22/2014)... Rock Hill, SC (PRWEB) October 22, 2014 ... the expansion of its cardiovascular pharmacogenetics menu, which ... improved patient outcomes. With PCLS’s evidence-based results, ... individual needs and optimize their therapy, while minimizing ... , In the U.S., according to the FDA ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Reverse Stock Split, Ticker Change and Launches New Corporate Website 2Report: Radical New IVD Test Approaches Key To Growth 2Report: Radical New IVD Test Approaches Key To Growth 3Shimadzu Releases QuantAnalytics Open Access LCMS Software Package for Clinical Applications 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 3
... Cause of ... Death, Yearly, Liver Cancer Alone ... Growing; Viral Hepatitis Declines, MILAN, April 23 More than 6,000 physicians ... the opening sessions of the 43rd Annual Meeting of the,European Association for the ...
... image are better than one for analyzing tumors , ... determine the amount of oxygen in a tumor very useful, because ... a poor outcome. A new method to do this and to ... been developed and used to image tumors in mice by Murali ...
... Some of the biggest-selling,biologics developed during the boom years ... and insulin, have lost patent,protection in the U.S. in ... $40 billion. This opens up a huge potential market ... a new report by Kalorama,Information, Biogenerics: the World Market ...
Cached Biology Technology:Liver Diseases: A Huge European Health Burden, But Some Trends are Positive 2Liver Diseases: A Huge European Health Burden, But Some Trends are Positive 3JCI table of contents: April 22, 2008 2JCI table of contents: April 22, 2008 3JCI table of contents: April 22, 2008 4JCI table of contents: April 22, 2008 5JCI table of contents: April 22, 2008 6JCI table of contents: April 22, 2008 7JCI table of contents: April 22, 2008 8JCI table of contents: April 22, 2008 9JCI table of contents: April 22, 2008 10JCI table of contents: April 22, 2008 11JCI table of contents: April 22, 2008 12Huge Potential in Biosimilars if Generic Providers Overcome Regulatory Hurdles 2
(Date:10/14/2014)... in Cancer Research shows SIRT6—a protein known ... promote the development of skin cancers by turning on ... sun-damaged skin cells. , Previously considered protective, SIRT6 is ... that help regulate genomic stability and prevent some of ... DNA damage, which can lead to cancer. This study, ...
(Date:10/14/2014)... N.Y. – Scientists have sequenced the house fly genome ... one might expect from an insect that thrives in ... published Oct. 14 in the journal Genome Biology ... biology and of how flies quickly adapt to resist ... Adult house flies (Musca domestica) carry and transmit more ...
(Date:10/14/2014)... new kind of stem cell that can become either a ... according to a study published today in the journal ... type contradicts current theory on how organs arise from cell ... of, and future treatment for, liver cancer., Thanks to stem ... being made up of more than 200 cell types. The ...
Breaking Biology News(10 mins):Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2House fly genome reveals expanded immune system 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
... provide a look at the ash and gas clouds being ... NOAA,s GOES-13 satellite to provide a week long look at ... westerly winds carry the debris (ash and smoke) far to ... down the ash before it can go far in the ...
... 2012 Scientists at The Scripps Research Institute have ... the market to treat neuropathic pain and epilepsy, helps ... treatments, gabapentin targets stress systems in the brain that ... 12-week trial of 50 treatment-seeking cannabis users, those who ...
... /PRNewswire-iReach/  -- Global Information Inc. is announces limited time ... important Boston healthcare conferences: Next-Gen Kinase ... rapidly maturing kinase inhibitors field will gather to explore ... Next-Gen Kinase Inhibitors Conference in Cambridge, MA. ...
Cached Biology News:NASA's new satellite movie of 1 week's ash activity from Mexico's Popocatepetl Volcano 2Scripps research scientists find anticonvulsant drug helps marijuana smokers kick the habit 2Scripps research scientists find anticonvulsant drug helps marijuana smokers kick the habit 3Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27 2Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27 3
Economical and manually filled LN2 vacuum insulated storage container offers high capacity and low nitrogen consumption while offering convenient storage of samples....
... DNase I Amplification Grade ... DNA to oligodeoxyribonucleotides. The ... units/mg. DNAse I Amplification ... and tested for absence ...
... of Cell Cultures (ECACC) in conjunction with ... West of England, Bristol, UK, have produced ... of HER2, oestrogen and progresterone receptor assays. ... of formalin fixed, breast cancer cell lines; ...
... 3C protease from human rhinovirus (HRV 3C) ... brand line of restriction grade proteases. The ... 6XHis-fusion protein, which recognizes the same cleavage ... small, 22 KDa size of the protease, ...
Biology Products: