CENTER VALLEY, Pa., April 4, 2008 /PRNewswire/ -- Scientists in fields as diverse as pharmaceutical research, food science and biology will benefit from the Olympus FluoroPoint(TM) single molecule fluorescence detection system for molecular interaction analysis. Already in use in scores of laboratories around the world, the system, with its high sensitivity, low sample volumes, flexibility and ease of use, is now available for the first time to U.S. screening and research laboratories.
FluoroPoint provides scientists with highly accurate and reliable data for studies involving protein-protein interactions, DNA, RNA, receptor binding, siRNA, SNP genotyping, enzyme reactions, polymerization, thermodynamics, and other processes and mechanisms. Useful in a wide variety of facilities, it provides absolute quantification, rather than the relative or proportional measurements generated by other techniques. The system is highly sensitive, yielding accurate results for sample volumes as small as 30 microliters, thus allowing the conservation of precious samples. Compatible with 384-well plates and using a plate reader format, FluoroPoint is easily adopted by pharmaceutical companies for drug discovery activities, and provides complementary technology to core facilities and other life science research laboratories.
Biological systems are often more complex and less predictable than the molecular contexts generally interrogated by biophysicists and chemists. Whereas typical molecular interaction experiments (using techniques such as surface plasmon resonance, for instance) use a defined selection of molecules, FluoroPoint can accurately and specifically perform single molecule detection in environments that are similar to the physiological conditions found in living organisms. In contrast to fluorescence plate readers, which only make aggregate measurements, FluoroPoint delivers true single molecule data, long trusted by biophysicists.
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