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Olympus FluoroPoint(TM) System Provides High-Sensitivity Single Molecule and Protein Interaction Analysis for Screening and Research
Date:4/4/2008

CENTER VALLEY, Pa., April 4, 2008 /PRNewswire/ -- Scientists in fields as diverse as pharmaceutical research, food science and biology will benefit from the Olympus FluoroPoint(TM) single molecule fluorescence detection system for molecular interaction analysis. Already in use in scores of laboratories around the world, the system, with its high sensitivity, low sample volumes, flexibility and ease of use, is now available for the first time to U.S. screening and research laboratories.

FluoroPoint provides scientists with highly accurate and reliable data for studies involving protein-protein interactions, DNA, RNA, receptor binding, siRNA, SNP genotyping, enzyme reactions, polymerization, thermodynamics, and other processes and mechanisms. Useful in a wide variety of facilities, it provides absolute quantification, rather than the relative or proportional measurements generated by other techniques. The system is highly sensitive, yielding accurate results for sample volumes as small as 30 microliters, thus allowing the conservation of precious samples. Compatible with 384-well plates and using a plate reader format, FluoroPoint is easily adopted by pharmaceutical companies for drug discovery activities, and provides complementary technology to core facilities and other life science research laboratories.

Biological systems are often more complex and less predictable than the molecular contexts generally interrogated by biophysicists and chemists. Whereas typical molecular interaction experiments (using techniques such as surface plasmon resonance, for instance) use a defined selection of molecules, FluoroPoint can accurately and specifically perform single molecule detection in environments that are similar to the physiological conditions found in living organisms. In contrast to fluorescence plate readers, which only make aggregate measurements, FluoroPoint delivers true single molecule data, long trusted by biophysicists.

FluoroPoint offers fluorescence correlation spectroscopy (FCS), molecular brightness (FIDA), and confocal anisotropy (FIDA-PO) measurements, all in an automated, user-friendly format. Its mix-and-measure simplicity means that researchers do not have to do any washing or other complicated preparatory efforts. Data is available as quickly as 0.5 seconds per well, depending on the measurements collected.

For more information on the Olympus FluoroPoint molecular interaction analysis system, contact Olympus America Inc., 3500 Corporate Parkway, Center Valley PA 18034-0610; phone 1-908-596-0417; visit http://www.olympusamerica.com/FluoroPoint or email FluoroPoint@olympus.com.

About Olympus Products for Life Science, Biotechnology and Pharmaceutical Research

Olympus America is a recognized leader in applying optical technology for life science research. With proven expertise in providing advanced systems to power research, Olympus delivers a portfolio of products for drug discovery, biotechnology and the life sciences, including microscopes, endoscopes and surgical instruments, along with diagnostic and scientific instruments, cameras and software.

About Olympus

Olympus is a precision technology leader, creating innovative opto-digital solutions in healthcare, life science and consumer electronics products. Olympus works collaboratively with its customers and its affiliates worldwide to leverage R&D investment in precision technology and manufacturing processes across diverse business lines. These include:
-- Gastrointestinal endoscopes, accessories, and minimally invasive

surgical products;

-- Advanced clinical and research microscopes;

-- Lab automation systems, chemistry-immuno and blood bank analyzers and

reagents;

-- Digital cameras and voice recorders.

Olympus serves healthcare and commercial laboratory markets with integrated product solutions and financial, educational and consulting services that help customers to efficiently, reliably and more easily achieve exceptional results. Olympus develops breakthrough technologies with revolutionary product design and functionality for the consumer and professional photography markets, and also is the leader in gastrointestinal endoscopy and clinical and educational microscopes. For more information, visit http://www.olympusamerica.com.

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