Navigation Links
Not the protein, but its location in the cell, determines the onset of leukemia
Date:7/10/2008

kinase inhibitors are usually used to combat these kinds of cancers. However, the carcinogenic kinase often becomes resistant to these inhibitors − which is certainly true for T-ALL. So, scientists are actively seeking alternative approaches.

De Keersmaecker's recent research results now offer a possibility. Indeed, the scientists have shown in cells that NUP214-ABL1 is no longer carcinogenic when it cannot bind with the protein complex in the vicinity of the cell nucleus. On the basis of these results, the researchers want to further investigate the therapeutic possibilities of compounds that render binding between the complex and NUP214-ABL1 impossible. This study also indicates that the location of proteins can play an important role in other forms of cancer/leukemia as well.


'/>"/>

Contact: Joke Comijn
Joke.comijn@vib.be
329-244-6611
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Page: 1 2

Related biology technology :

1. The PLSG Invests $150,000 in Coventina Healthcare Enterprises, Inc., Its Eighth Company Relocation to Pittsburgh
2. Clinsys Clinical Research, Inc. Announces Relocation of Corporate Headquarters
3. AMDL Signs 100 Strategic Cooperation Agreements in China for Its JPGreen Clinics; Gross Sales Per Each Location Could Exceed $400,000
4. Time Domain Showcases Precision Location Capability of Ultra Wideband PLUS Product Line at HIMSS 2008
5. Surface dislocation nucleation: Strength is but skin deep at the nanoscale, Penn engineers discover
6. Caliper Life Sciences Announces Date and Location of its 2008 Annual Meeting of Stockholders
7. Expansion and Relocation to New, State-Of-The-Art Facilities Marks Milestone in Effort to Roll Out New Tool for Cancer Diagnosis
8. RainDance Announces Company Relocation and Manufacturing Startup
9. Cord Blood America Reports CorCell, Its Major Acquisition in 2006, Turns Profitable
10. Court Determines that University of Pittsburgh and Artecel Have Sole Rights to Adipose-Derived Stem Cell Patent
11. Genzyme Study of Myozyme(R) for Late-Onset Pompe Patients Meets Co-Primary Efficacy Endpoints
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 21, 2015 Cambridge Semantics, the leading provider ... announced that 2014 was a record-breaking year across the board ... the Anzo Smart Data Platform and our Smart Data solutions, ... from diverse data which led to record growth for the ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting to the ... consultants, Protocol Networks has recently announced its expansion into ... his company has attracted several clients in The Constitution ... as others. With the success of these engagements, Rogers ...
(Date:1/22/2015)... California (PRWEB) January 22, 2015 Pipette.com ... Offer to their comprehensive portfolio of Eppendorf products. ... customers to purchase a Centrifuge 5424/5424 R and receive ... of either Eppendorf Research plus or Eppendorf Reference 2 ...
(Date:1/22/2015)... 2015 Dr. Greg Leyer of UAS Labs ... Natural Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... continuing education conference for health care professionals. This year’s pre-conference ... of probiotics in health. Dr. Leyer spoke about the emerging ...
Breaking Biology Technology:Cambridge Semantics Announces Record Results for 2014 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
... relying on existing telecommunications satellites, has put a second satellite ... weather information clients. , ,Last September, Loral Skynet ... and rerouted its customers to Telstar 5 and 6. The ... Birch, data services product manager for Weather Central, said his ...
... startups, biotech , ,Entrepreneurship, nanotechnology and biomedical engineering ... in Madison and Milwaukee, giving substance to what Wisconsin ... , , Tips for Entrepreneurs , ,Established entrepreneurs ... Entrepreneurs Conference , which runs June 1-2 at the ...
... MILWAUKEE Advocates of Windows and open-source software vied ... presentation of Wednesdays session of the ITEC conference in ... Labs , said that open-source software provides a technically ... companies that want a single, obvious place to turn ...
Cached Biology Technology:Doyles Entrepreneurs and Research week nears 2Doyles Entrepreneurs and Research week nears 3Linux and Windows duke it out at ITEC 2Linux and Windows duke it out at ITEC 3
(Date:1/22/2015)... , Europe,s most ... Patent Office to present a video retrospective of the most exciting ... Christofer Toumazou and Sophie Wilson   ... the Award   Starting on 22 January 2015 on   ...
(Date:1/22/2015)... Jan. 22, 2015 Infinisource has launched its new NXG ... model. The G2 sets a higher standard for collecting attendance ... management solution. With plug-and-play installation, touch screen interface and seamless ... a robust time collection solution for the small to mid-size ...
(Date:12/22/2014)... 22, 2014 Research and Markets ( ... "The Global Watermarking and Fingerprinting Markets" ... http://photos.prnewswire.com/prnh/20130307/600769 This insight provides ... and fingerprinting markets. Watermarking aims to control and ...
Breaking Biology News(10 mins):Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3Infinisource's NXG series sets new time clock standard 2The Global Watermarking and Fingerprinting Markets 2
... 2013 -- American Associates, Ben-Gurion University of the Negev (AABGU) ... late Dr. Jordan Baruch, to fund stem cell research at ... The Jordan Baruch Stem Cell Research Fund was dedicated at ... Baruch and 20 members of her extended family. "Jordan ...
... new study has found that tamoxifen, a well-known breast ... mouse model of Duchenne muscular dystrophy (DMD). At present, ... the symptoms in boys with DMD, a debilitating muscular ... and cardiac impairments, paralysis, and premature death. This study ...
... TORONTO, Jan 14, 2013Taking a vitamin D supplement and drinking ... how much vitamin D is in a child,s body, new ... than even skin colour and exposure to the sun, according ... Michael,s Hospital. "Early childhood is a critical stage in ...
Cached Biology News:Ben-Gurion U. establishes stem cell research fund in honor of inventor Jordan Baruch 2Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy 2Supplements and cow's milk play biggest roles in determining vitamin D levels in children 2
...
MultiWash III w/ 12-portStandard Manifold...
... 5 ml. The same high performance ... columns for fast, reliable purification of ... 5/50 GL, XK 16/20, or other ... required.Extremely useful for exploiting either the ...
...
Biology Products: