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Nieuwe behandeloptie vandaag geïntroduceerd voor artsen die patiënten behandelen met veelvuldig recidiverend of refractair agressief B-cel-non-hodgkinlymfoom
Date:11/7/2012

SEATTLE, Washington, November 7, 2012 /PRNewswire/ --

Cell Therapeutics, Inc. ("CTI") (NASDAQ en MTA: CTIC), een bedrijf dat zich richt op het vertalen van wetenschap naar nieuwe kankertherapieën, heeft vandaag bekend gemaakt dat Pixuvri® (pixantron) in Nederland beschikbaar is. In mei 2012 is voor pixantron in de Europese Unie (EU) voorwaardelijke goedkeuring verleend en dit is de eerste, in de EU goedgekeurde behandeling voor volwassen patiënten met veelvuldig recidiverend of refractair agressief B-cel-non-hodgkinlymfoom ('NHL'). In het EXTEND (Expanding the reach of anthracyclines with piXanTronE in relapsed or refractory aggressive NHL Disease) -onderzoek naar pixantron bereikten met pixantron meer patiënten een volledige respons of niet-bevestigde volledige respons en duurde het ook langer voor hun ziekte verergerde dan met andere monotherapeutische behandelingen.[1]

"Er bestaat echt behoefte aan een nieuwe behandeloptie bij de behandeling van agressief recidiverend NHL," aldus Professor Anton Hagenbeek, hoogleraar hematologie verbonden aan het Academisch Medisch Centrum (AMC) in Nederland. "Momenteel zijn er voor patiënten die geen respons vertonen op tweedelijnsbehandeling en dus niet in aanmerking komen voor hooggedoseerde chemotherapie gevolgd door autologe stamceltransplantatie, maar beperkte opties en vaak kan hun alleen deelname aan een klinisch onderzoek of palliatieve zorg worden geboden. Pixantron is een belangrijke nieuwe ontwikkeling met objectieve responspercentages van 40% in deze specifieke subgroepen van 'poor-risk' patiënten waar zowel artsen als patiënten blij mee zullen zijn."

In de EU doen zich jaarlijks ongeveer 37.000 nieuwe gevallen van agressief B-cel-NHL voor.[2],[3] Patiënten met recidiverend/refractair NHL krijgen doorgaan
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SOURCE Cell Therapeutics Inc.
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