Navigation Links
Nexavar Data to be Presented at 46th American Society of Clinical Oncology Annual Meeting
Date:5/20/2010

nd individual investigators as a single agent or as a combination treatment in a wide range of cancers, including lung, thyroid, breast, ovarian, and colorectal cancer and as an adjuvant therapy for liver and kidney cancer. 

Important Safety Considerations For Patients Taking Nexavar

Based on the currently approved U.S. package insert for the treatment of patients with unresectable hepatocellular carcinoma and advanced kidney cancer, hypertension may occur early in the course of therapy and blood pressure should be monitored weekly during the first six weeks of therapy and treated as needed.  In HCC patients, bleeding with a fatal outcome from any site was reported in 2.4% for Nexavar and 4% in placebo.  The incidence of treatment-emergent cardiac ischemia/infarction was 2.7% for Nexavar vs. 1.3% for placebo.  In RCC patients, incidence of bleeding regardless of causality was 15% for Nexavar vs. 8% for placebo and the incidence of treatment-emergent cardiac ischemia/infarction was 2.9% for Nexavar vs. 0.4% for placebo.  Most common adverse events >/=20% related to Nexavar for both HCC and RCC were fatigue, weight loss, rash/desquamation, hand-foot skin reaction, alopecia, diarrhea, nausea, and abdominal pain.  Grade 3/4 adverse events in HCC and RCC patients, respectively, were 45% for Nexavar vs. 32% for placebo and 38% for Nexavar and 28% for placebo.  Women of child-bearing potential should be advised to avoid becoming pregnant and advised against breast-feeding.  In cases of any severe or persistent side effects, temporary treatment interruption, dose modification or permanent discontinuation should be considered.

For information about Nexavar including U.S. Nexavar prescribing information, visit

SOURCE Bayer HealthCare Pharmaceuticals, Inc.; Onyx Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related biology technology :

1. Onyx Pharmaceuticals Announces a Teleconference and Webcast to Provide an Update on Nexavar and Report Full Year 2007 Financial Results
2. Bayer and Onyx Announce Nexavar Data Presentations at 44th American Society of Clinical Oncology Annual Meeting
3. Onyx Pharmaceuticals Announces a Teleconference and Webcast to Provide an Update on Nexavar
4. Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting
5. Three Studies by Independent Scientists Highlighting Pressure Cycling Technology (PCT) to be Presented this Week at the British Mass Spectrometry Societys 29th Annual Meeting
6. Survival Data Presented From Phase II Study of Investigational Drug ZD4054 in Hormone-Resistant Prostate Cancer Patients
7. New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrines Anti-PS Technology Platform
8. Results of Colon Cancer Study Utilizing Pressure Cycling Technology (PCT) Presented at the American College of Gastroenterology Annual Scientific Meeting
9. Kuvan, Naglazyme and Aldurazyme Data to Be Presented at the 57th Annual Meeting of the American Society of Human Genetics
10. Micromet Data Presented at the International AACR-NCI-EORTC Conference Support the Development of Adecatumumab (MT201) in Earlier Stage Cancer Disease Settings
11. Three PDX (Pralatrexate) Studies Presented at the 2007 AACR-NCI-EORTC Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Biofeedback – When a ... diagnosed, selecting medication to best treat it can become ... by using electroencephalography (EEG) can help predict which medicine ... risk of adverse drug events. , The article ... the current issue of the journal Biofeedback offers evidence ...
(Date:7/21/2014)... Hills, IL (PRWEB) July 21, 2014 ... control, and simple programming, the new Cole-Parmer® ... Head is easy to operate for automated ... cycles for hands-free dispensing. The batch count function ... cumulative volume or totalizer tracks amount dispensed across ...
(Date:7/21/2014)... , July 21, 2014  Mike Patterson, ... of $1.6 million in Series Seed B funding ... chemical sensors for the life science, defense, intelligence, ... Capital Partners led the round and was joined ... Angels.  Said Patterson , "This round of ...
(Date:7/20/2014)... July 20, 2014 NSG Precision ... glass optics, and spectrophotometer calibration standards ... NSG has released many products that have transformed ... has been their solid-state calibration standards. , NSG’s ... since their release in 2008. NSG started ...
Breaking Biology Technology:Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 2Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 3New Easy-View Cole-Parmer Digital Gear Pump Drive Makes Performance Monitoring Effortless 2Global Graphene Manufacturing Leader, Graphene Frontiers, Receives Series Seed B Funding To Assure Production Of The Next Generation Of Biological And Chemical Sensor Technology 2How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 2How NSG Precision Cells Spectrophotometer Calibration Standards Makes NIR Work Easier 3
... May 28 CV Therapeutics,Inc. (Nasdaq: CVTX ... rule 4350, the Company issued new inducement stock ... primarily in connection,with its commercialization efforts in the ... an aggregate 151,800 shares of,common stock and are ...
... May 28 Abt Associates announced that,it has ... Officer.,Small most recently served as Senior Vice President, ... Inc., a $700 million,provider of factory and tool ... Prior to joining Brooks Automation he held the,position ...
... Ohio, May 28 NanoLogix, Inc. (Pink,Sheets: NNLX) ... updates:, NanoLogix personnel will showcase company technology ... Exhibition in Boston, June 1-5 2008. The ASM,meeting ... NanoLogix will be Dr. Sergey Gazenko and CEO ...
Cached Biology Technology:CV Therapeutics Reports Option Grants Under Nasdaq Marketplace Rule 4350 2Abt Associates Names Richard Small Vice President and Chief Financial Officer 2NanoLogix Inc. to Present at The American Society for Microbiology (ASM) General Meeting in Boston; Announces Product Line and Provides Operations Update 2
(Date:7/21/2014)... to monitor seals, every movement, researchers have shown for ... to offshore wind farms and pipelines. Those man-made structures ... according to a study published in the Cell Press ... , "I was shocked when I first saw the ... Shoal," an offshore wind farm in the United Kingdom, ...
(Date:7/21/2014)... Want to conserve water and save on your utility ... and published in the current issue of the journal ... List: The Most Effective Actions U.S. Households Can Take ... water use substantially by simple actions such as installing ... consumption. While the suggestions may be familiar, the researchers ...
(Date:7/21/2014)... Dysfunction in dopamine signaling profoundly changes the ... brain,s prefrontal cortex and may be an underlying ... schizophrenia, according to UC Irvine scientists. , This ... that receive this neurotransmitter showed for the first ... of behavioral and physiological functions regulated in the ...
Breaking Biology News(10 mins):Seals forage at offshore wind farms 2Researchers provide guide to household water conservation 2Researchers provide guide to household water conservation 3UCI researchers find epigenetic tie to neuropsychiatric disorders 2
... things that suffer from stress. Trees must deal with stress ... too much water, from scarcity of a needed nutrient, from ... to stress quickly and efficiently is a pressing goal of ... University scientists has identified the molecular mechanism that Populusthe scientific ...
... A recent research study has shown that food ... food due to resource constraints, can lead to greater ... "Prior studies have shown that women living ... health complications," said Craig Gundersen, a University of Illinois ...
... scientists have analysed the temperature and salt levels of the ... evolution of each variable. Their research shows that, since at ... and saltier, and that, since the 1990s, this process has ... layer of the Western Mediterranean increases by 0.002C, and its ...
Cached Biology News:Feeling stressed? So is the poplar 2Food insecurity increases risk of weight gain and complications during pregnancy 2Temperature and salt levels of the Western Mediterranean are on the increase 2
Anti-Rsk2/MAPKAP Kinase 1b, #0 SK2/MAPKAP K1 beta Smartpool&t 3T3 cell lysate Non-specific Control Pool , #D 1X Universal Buffer...
TNF-R2 (L-20)...
... The PowerEase 500 Power ... mini-gel electrophoresis. It offers extensive ... and four custom methods for ... own preferences. The simple intuitive ...
Eliminate electrical interference from any analog signal, without filtering. Ideal for electrophysiology applications like EKG, EMG, and EEGs. Removes 50/60hz noise and harmonics caused by grounding ...
Biology Products: