Navigation Links
NexBio(R) Demonstrates DAS181 (Fludase(R)*), a Broad-Spectrum Drug Candidate, Inhibits Influenza Viral Infection in Human Lung Tissue
Date:8/25/2009

"DAS181 is a particularly important potential new broad-spectrum drug for influenza because as an entry blocker, it works by a mechanism of action different from all other antiviral drugs either on-market or in development," said John M. Nicholls, M.D., Associate Professor, Department of Pathology, the University of Hong Kong, one of the two corresponding authors on the publication. "Our study clearly shows DAS181's remarkable effectiveness in protecting fresh human tissue from infection by a highly lethal H5N1 strain. Though the world is currently coping with a pandemic caused by a much less virulent H1N1 strain, DAS181 has shown significant inactivation of both types of influenza receptors found in the human airways."

In the "Report To The President On U.S. Preparations For 2009-H1N1 Influenza" by the President's Council of Advisors on Science and Technology (PCAST) announced yesterday, it is recommended that "It will be important to develop new classes of drugs to expand the armamentarium. A particularly promising new approach is to develop drugs that block the virus by acting on a human cellular function ('host target'), rather than a viral protein ('pathogen target'), because such drugs should be less likely to encounter acquired resistance." DAS181 development takes this "promising new approach."

NexBio will be presenting data on DAS181 activity against Novel H1N1 and against seasonal influenza isolates from winter 2008-09 that are resistant to Tamiflu((R)) in in vitro, ex vivo and in vivo models at the upcoming Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) annual meeting in San Francisco, CA on Tuesday, September 15, 2009.

ABOUT NEXBIO

NexBio, Inc. is a privately held development-stage biopharmaceutical company located in San Diego. NexBio's mission is to save lives and to improve the quality of life by creatin
'/>"/>

SOURCE NexBio, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals Lead Antibody
2. Abbott HIV Test Demonstrates Earlier Disease Detection
3. BioNeutrals Ygiene(TM) Hospital Grade Antimicrobial Demonstrates a 99.9997% Kill Rate Against Clostridium Difficile Spores (C.diff) in Independent Lab Pre-testing Phase
4. New Pre-Clinical Data on OmniGuides BeamPath NEURO(TM) Demonstrates Precise Cutting in Brain Tissue
5. Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia
6. PROSTVAC(TM) Data Presented at the ASCO Meeting Demonstrates the Potential for Significant Increases in Life Expectancy in Late-Stage Prostate Cancer
7. NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS
8. OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial
9. SemBioSys plant-derived Apo AI(Milano) demonstrates encouraging biologic activity in seven preclinical models
10. OrbusNeichs Genous(TM) Bio-engineered R stent(TM) Demonstrates Impressive Results in Higher Risk Patients
11. Finesse Demonstrates TruFluor(TM) pH, a Single-Use Optical pH Sensor and Transmitter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 22, 2014 Research and Markets ... "Global DNA Diagnostics Market (Product types, Application, Technology, ... Trends, Company Profiles, Demand, Insights, Analysis, Research, Report, ... report to their offering. This ... techniques, end users and Geography) Global Size, Industry ...
(Date:10/22/2014)... Involution Studios , a healthcare ... new infographic, Understanding Ebola . The goal ... easy to follow informative tool for anyone wanting to ... and prevention. , "As the news has spread in ... outbreak represents not only a healthcare crisis with global ...
(Date:10/22/2014)... October 22, 2014 According to ... by Service Type (Consulting, Integration, Deployment & Support), ... Deployment Model (Public, Private, Others (Hybrid & Community)) ... defines and segments the Cloud Professional Services Market ... forecasting of revenues. It also identifies the drivers ...
(Date:10/22/2014)... and HONG KONG , Oct. 22, ... therapeutics enterprise, announced today that rare disease expert ... vice president, research. Dr. McKew brings more than two ... positions at the National Institutes of Health, Wyeth Research ... Wyeth). Dr. McKew will lead aTyr,s efforts to expand and ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... Milwaukee and perhaps throughout Wisconsin will be asked to ... Milwaukee moves toward completion of its wireless Internet installation. ... a contract with Midwest Fiber Networks, LLC ... five goals that are key to bridging the digital ...
... doesn't mince words when it comes to broadband connectivity. , ... columnist for WTN Media , moving from dial-up Internet service ... stagecoach. Why bother when there is a Mercedes Benz ... is an issue most communities are faced with, and in Carlini's ...
... I want any old time. Lyrics from I'm Free ... this old Rolling Stones standard from the Sixties as a ... services targeted at Boomers with bloated bank balances (regretably only ... at helping people achieve their retirement dreams, it also aptly ...
Cached Biology Technology:Businesses could bridge digital divide in Milwaukee with used computers 2Businesses could bridge digital divide in Milwaukee with used computers 3Carlini beats drum for high-speed broadband 2Can a talent market work inside organizations? 2Can a talent market work inside organizations? 3Can a talent market work inside organizations? 4Can a talent market work inside organizations? 5Can a talent market work inside organizations? 6
(Date:10/16/2014)... wages war on the human body. Battles are ... In pancreatic cancer, this stalemate—known as tumor dormancy—can ... malignant, a phenomena that is poorly understood. ... laboratory of Salvatore Torquato, a Professor of Chemistry ... surrounding tumor dormancy and the switch to a ...
(Date:10/16/2014)... new synthesis of recent research findings to inform their ... two states. , The Ecology and Management of ... Synthesis of the Relevant Biophysical Science and Implications for ... the U.S. Forest Service,s Pacific Northwest Research Station, is ... a synthesis of the large body of scientific information ...
(Date:10/16/2014)... Although monocultures can be cultivated efficiently, they are ... water caused by monoculture cultivation is becoming increasingly ... principal crop form and are regarded as the ... production – quite wrongfully, finds Bernhard Schmid, an ... advocates a novel form of agriculture and forestry. ...
Breaking Biology News(10 mins):Modeling tumor dormancy 2New report synthesizes best available science on management of moist mixed-conifer forests 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3
... detailed analysis of ancient and modern DNA to show ... modern European beavers is due largely to human hunting., ... researcher Professor Michi Hofreiter, provides important new insights into ... Crucially, it shows the European beaver has been strongly ...
... and East Malling Research have identified a new way of ... on the UK,s valuable cherry and plum crops. Brown ... attacks stone fruit as well as causing blossom ... the use of fungicide treatments, but in some cases these ...
... are discussed, University of Washington researchers have found that ... reflect sunlight and curb the effects of global warming ... and supported by strict reductions in greenhouse gas (GHG) ... in IOP Publishing,s journal Environmental Research Letters , ...
Cached Biology News:Researchers shed new light on the genetic history of the European beaver 2Researchers warn against abrupt stop to geoengineering method 2
G-Protein Coupled Receptor Assay, For 500 assays. SPA. Category: Drug Screening & Cellular Assays, Assays ....
... 9 oligodeoxynucleotides are random ... at the 5' end ... Fluor dyes and they ... microarray spot morphology, hybridization ...
EDTA, disodium salt, 1 kg. Ethylene diaminetetraacetic acid.Dihydrate. Assay: 99.0-101.0%, nuclease-free.Risks: 36, 37, 38 ; Safety Precautions: 22, 36, 37. Category: Nucleotides & Enzymes & Biochemi...
Mycoplasma tested...
Biology Products: