Navigation Links
New injectable hydrogel encourages regeneration and improves functionality after a heart attack
Date:2/20/2013

University of California, San Diego bioengineers have demonstrated in a study in pigs that a new injectable hydrogel can repair damage from heart attacks, help the heart grow new tissue and blood vessels, and get the heart moving closer to how a healthy heart should. The results of the study were published Feb. 20 in Science Translational Medicine and clear the way for clinical trials to begin this year in Europe. The gel is injected through a catheter without requiring surgery or general anesthesia -- a less invasive procedure for patients.

There are an estimated 785,000 new heart attack cases in the United States each year, with no established treatment for repairing the resulting damage to cardiac tissue. Lead researcher Karen Christman, a professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering, said the gel forms a scaffold in damaged areas of the heart, encouraging new cell growth and repair. Because the gel is made from heart tissue taken from pigs, the damaged heart responds positively, creating a harmonious environment for rebuilding, rather than setting off a chain of adverse immune system defenses.

"While more people today are initially surviving heart attacks, many will eventually go into heart failure," said Christman. "Our data show that this hydrogel can increase cardiac muscle and reduce scar tissue in the region damaged by the heart attack, which prevents heart failure. These results suggest this may be a novel minimally invasive therapy to prevent heart failure after a heart attack in humans."

The hydrogel is made from cardiac connective tissue that is stripped of heart muscle cells through a cleansing process, freeze-dried and milled into powder form, and then liquefied into a fluid that can be easily injected into the heart. Once it hits body temperature, the liquid turns into a semi-solid, porous gel that encourages cells to repopulate areas of damaged cardiac tiss
'/>"/>

Contact: Catherine Hockmuth
chockmuth@ucsd.edu
858-822-1359
University of California - San Diego
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In Neptune Technologies & Bioressources Inc. To Contact The Firm
3. Wysebridge Encourages Taking The Patent Bar Before Major Exam Changes Are Implemented
4. Maker of leading in-home HIV test encourages testing
5. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess of $100,000 Investing In Keryx Biopharmaceuticals, Inc. To Contact the Firm
6. Mandy Moore Campaigns for Clean Water, GreenBeanBuddy Encourages Mothers to Help Through the Use of Green Cleaning Products
7. Scientists identify mammal model of bladder regeneration
8. New material interface improves functioning of non-silicon-based electronic devices
9. Study improves understanding of surface molecules in controlling size of gold nanoparticles
10. Bioreactor redesign dramatically improves yield
11. Novel compound halts tumor spread, improves brain cancer treatment in animal studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New injectable hydrogel encourages regeneration and improves functionality after a heart attack  
(Date:9/2/2015)... , Sept. 2, 2015 Australian prostate ... a prestigious Australian science prize recognising ,outstanding, science that ... track to globally launch a novel prostate cancer diagnostic ... a high level consortium taking out the peer-reviewed Australian ... Scientific Research. This prize is awarded ...
(Date:9/2/2015)... Colo. , Sept. 2, 2015 Aytu ... on developing treatments for urological and related conditions, announced ... its planned private placement convertible note financing, raising a ... prior tranches totaling $3.175 million. ... "Proceeds from this private placement are intended to be ...
(Date:9/2/2015)... FRANCISCO, Calif. , Sept. 2, 2015 ... Bonnie H. Anderson , president and chief executive ... Conference on Wednesday, September 16, 2015 at 10:30 a.m. ... The live audio webcast and subsequent ... . The webcast will be available shortly after conclusion ...
(Date:9/2/2015)... , September 2, 2015 ... ("BioLight" or the "Company"), a firm that invests ... and cancer diagnostics, announced today that presentations highlighting ... will be delivered at the Ophthalmology Futures European ... Society of Cataract & Refractive Surgeons ("ESCRS"), both ...
Breaking Biology Technology:Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 2Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 3Aytu BioScience Completes $5.175 Million Private Placement 2Aytu BioScience Completes $5.175 Million Private Placement 3Veracyte to Present at Morgan Stanley Global Healthcare Conference 2Presentations to Highlight BioLight's IOPtiMate[TM] System at Upcoming European Ophthalmology Conferences 2Presentations to Highlight BioLight's IOPtiMate[TM] System at Upcoming European Ophthalmology Conferences 3
... Biotech Inc. (TSX:,ONC, NASDAQ: ONCY) ("Oncolytics") has ... Neoplastic Cells from Mixed Cellular,Compositions using Viruses." ... cells ex vivo from blood stem cells ... vaccinia viruses, herpes simplex,viruses, parapoxviruses and adenoviruses., ...
... /PRNewswire-FirstCall/ - SemBioSys Genetics Inc. (TSX:,SBS), a biotechnology ... and cardiovascular diseases, today announced that it,has signed ... S.A. (INDEAR) based in Rosario, Argentina. INDEAR is ... S.A. and Bioceres S.A. to develop,manufacturing and development ...
... Jan. 29 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX:,ARI), ... wave of,antibody therapeutics, today announced its financial and ... ended November 30, 2007., "Fiscal 2007 was ... the,significant advancement we made with the pre-IND programs ...
Cached Biology Technology:Oncolytics Biotech Inc. Announces Issuance of 8th Canadian Patent 2SemBioSys signs option agreement for safflower-produced food ingredient 2SemBioSys signs option agreement for safflower-produced food ingredient 3ARIUS announces fourth quarter and year-end fiscal 2007 financial results 2ARIUS announces fourth quarter and year-end fiscal 2007 financial results 3ARIUS announces fourth quarter and year-end fiscal 2007 financial results 4ARIUS announces fourth quarter and year-end fiscal 2007 financial results 5ARIUS announces fourth quarter and year-end fiscal 2007 financial results 6ARIUS announces fourth quarter and year-end fiscal 2007 financial results 7ARIUS announces fourth quarter and year-end fiscal 2007 financial results 8ARIUS announces fourth quarter and year-end fiscal 2007 financial results 9ARIUS announces fourth quarter and year-end fiscal 2007 financial results 10ARIUS announces fourth quarter and year-end fiscal 2007 financial results 11ARIUS announces fourth quarter and year-end fiscal 2007 financial results 12ARIUS announces fourth quarter and year-end fiscal 2007 financial results 13
(Date:8/12/2015)... 2015 As the digital payment ... and advanced biometrics technology is accelerating beyond expectations.  While ... on using their credit cards, the digital currency, mobile ... payment services led by companies in the space such ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ...
(Date:8/10/2015)... Germany , August 10, 2015 /PRNewswire/ ... world leader in Eye Tracking Technology for more than ... Eye Tracking Platform for integration into all consumer display ... designs for seamless integration of eye tracking into consumer ... and augmented reality smart glasses. Omnivision,s leading sensor technology ...
(Date:8/6/2015)... 6, 2015 Synaptics Inc. (NASDAQ: ... solutions, today announced collaboration with Microsoft on biometric ... Microsoft leveraged Synaptics, deep expertise in human interface ... Through stringent testing, Synaptics, advanced image ... Microsoft,s Precision TouchPad (PTP) specification empowering OEMs with ...
Breaking Biology News(10 mins):Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Synaptics Chosen for Human Interface Co-Development on Windows 10 2
... and subsequently get a pounding headache? According to ... products, caffeine withdrawal is often characterized by a ... experiencing difficulty concentrating. Researchers from the University of ... of Medicine sought to investigate the biological mechanisms ...
... the United States are fragmented and insufficiently coordinated, failing ... entering the country. So reports a team of ... University, the Centers for Disease Control and Prevention, and ... their findings is published in this week,s issue of ...
... When Dr. Paul Naour was looking for a ... tape recording of a conversation regarding human behavior between ... at Great Ape Trust, a scientific research institute in ... language, culture, tools and intelligence. In E.O. Wilson and ...
Cached Biology News:Your brain on -- and off -- caffeine 2Wildlife trade threatens public health and ecosystems 2Wildlife trade threatens public health and ecosystems 3Rumbaugh's theory links positions of Wilson, Skinner 2Rumbaugh's theory links positions of Wilson, Skinner 3Rumbaugh's theory links positions of Wilson, Skinner 4
Request Info...
Mouse monoclonal [2D7/1] to E.coli LPS ( Abpromise for all tested applications). Antigen: Tissue / cell preparation: Escherichia coli J5 cells....
fli-1...
Purified Mouse anti-Hu p120 Catenin (pT916) Storage Temperature: Refrigerate(2 to 8C)...
Biology Products: