Navigation Links
New injectable hydrogel encourages regeneration and improves functionality after a heart attack
Date:2/20/2013

University of California, San Diego bioengineers have demonstrated in a study in pigs that a new injectable hydrogel can repair damage from heart attacks, help the heart grow new tissue and blood vessels, and get the heart moving closer to how a healthy heart should. The results of the study were published Feb. 20 in Science Translational Medicine and clear the way for clinical trials to begin this year in Europe. The gel is injected through a catheter without requiring surgery or general anesthesia -- a less invasive procedure for patients.

There are an estimated 785,000 new heart attack cases in the United States each year, with no established treatment for repairing the resulting damage to cardiac tissue. Lead researcher Karen Christman, a professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering, said the gel forms a scaffold in damaged areas of the heart, encouraging new cell growth and repair. Because the gel is made from heart tissue taken from pigs, the damaged heart responds positively, creating a harmonious environment for rebuilding, rather than setting off a chain of adverse immune system defenses.

"While more people today are initially surviving heart attacks, many will eventually go into heart failure," said Christman. "Our data show that this hydrogel can increase cardiac muscle and reduce scar tissue in the region damaged by the heart attack, which prevents heart failure. These results suggest this may be a novel minimally invasive therapy to prevent heart failure after a heart attack in humans."

The hydrogel is made from cardiac connective tissue that is stripped of heart muscle cells through a cleansing process, freeze-dried and milled into powder form, and then liquefied into a fluid that can be easily injected into the heart. Once it hits body temperature, the liquid turns into a semi-solid, porous gel that encourages cells to repopulate areas of damaged cardiac tiss
'/>"/>

Contact: Catherine Hockmuth
chockmuth@ucsd.edu
858-822-1359
University of California - San Diego
Source:Eurekalert  

0

GOOD

Page: 1 2

Related biology technology :

1. Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In Neptune Technologies & Bioressources Inc. To Contact The Firm
3. Wysebridge Encourages Taking The Patent Bar Before Major Exam Changes Are Implemented
4. Maker of leading in-home HIV test encourages testing
5. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess of $100,000 Investing In Keryx Biopharmaceuticals, Inc. To Contact the Firm
6. Mandy Moore Campaigns for Clean Water, GreenBeanBuddy Encourages Mothers to Help Through the Use of Green Cleaning Products
7. Scientists identify mammal model of bladder regeneration
8. New material interface improves functioning of non-silicon-based electronic devices
9. Study improves understanding of surface molecules in controlling size of gold nanoparticles
10. Bioreactor redesign dramatically improves yield
11. Novel compound halts tumor spread, improves brain cancer treatment in animal studies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New injectable hydrogel encourages regeneration and improves functionality after a heart attack  
(Date:5/17/2013)... (PRWEB) May 17, 2013 Oven Industries ... capabilities. The 5R6-900 temperature controller has many user-friendly benefits. ... plugged into the wall as a self-contained temperature ... This distinctive detail makes the device unique, as well ... controller can also be used universally, which allows the ...
(Date:5/17/2013)... release is available in German . ... well: with the naked eye, you can see which branch ... the blur of branches through the telephoto lens for high-magnification ... researchers who are looking to study proteins, the active biomolecules ... Zurich,s Institute for Molecular Systems Biology, and her colleagues have ...
(Date:5/17/2013)... 2013 The new Public-Private Partnership (PPP) ... the association’s recent annual meeting drew praise from community ... Kroes, who called the action “a huge step forward ... to European innovation.” , The Board of Stakeholders voted ... Photonics PPP at its 29 April meeting in Brussels, ...
(Date:5/17/2013)... , May 17, 2013 ... the most innovative thought leaders of the medical ... Manufacturing East conference and expo, from June 18-20 ...      (Photo: http://photos.prnewswire.com/prnh/20130517/613829 ) , ... to deliver industry professionals practical presentations and implementable ...
Breaking Biology Technology:New Temperature Control Products Announced by Oven Industries Inc. 2Proteome atlas for the tuberculosis pathogen 2Proteome atlas for the tuberculosis pathogen 3SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 2SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 3MedTech Innovate Seminars: New Interactive Learning Forums at 2013 MD&M East 2
... the world over are striving to develop organic solar cells ... that could be widely used to generate electricity. But ... form the proper structure at the nanoscale (tinier than 2-millionths ... to electricity. The goal is to develop cells made from ...
... , , , , ... Inc. (Nasdaq: PARD ), a biopharmaceutical company focused on ... 30, 2009, and provided a corporate update. , , ... we reported promising Phase 2 picoplatin data from our colorectal and ...
... , LYNBROOK, N.Y., Aug. 4 ... biopharmaceutical company developing first in class collagenase-based products, announced today ... audio webcast at 4:30 p.m. ET on Wednesday, August 12, ... corporate highlights. , , To participate ...
Cached Biology Technology:Plastics that convert light to electricity could have a big impact 2Plastics that convert light to electricity could have a big impact 3Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 2Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 3Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 4Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 5Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 6Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 7Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update 8BioSpecifics Technologies Corp. to Host Conference Call to Report Second Quarter 2009 Financial Results on August 12, 2009 2
(Date:5/16/2013)... entirety of an individual,s DNA is examined to look ... health problems is a massively useful technology for diagnosing ... problems if used incorrectly, say new recommendations from the ... today (16 May 2013) in the European Journal ... genome and on exome* sequencing and analysis are now ...
(Date:5/16/2013)... 16, 2013 Reportlinker.com announces that ... in its catalogue: Global ... http://www.reportlinker.com/p01181929/Global-Biometric-Systems-Market-Forecast--Opportunities-2018.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Security_Systems ... practises such as photographs, passwords and PIN ... technologies in last few years. Security threats ...
(Date:5/15/2013)... to date to examine the efficacy of PARP inhibitor ... breast and ovarian cancer, the oral drug olaparib was ... cancers. Results of the study, led by researchers from ... Pennsylvania and Sheba Medical Center in Tel Hashomer, Israel, ... Oncology,s annual meeting in Chicago in early June (Abstract ...
Breaking Biology News(10 mins):European Society of Human Genetics urges caution over use of new genetic sequencing techniques 2Global Biometric Systems Market Forecast & Opportunities, 2018 2Global Biometric Systems Market Forecast & Opportunities, 2018 3Global Biometric Systems Market Forecast & Opportunities, 2018 4Global Biometric Systems Market Forecast & Opportunities, 2018 5Global Biometric Systems Market Forecast & Opportunities, 2018 6Global Biometric Systems Market Forecast & Opportunities, 2018 7PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations 2
... 2012) The National Eye Institute has awarded researchers ... Mass. Eye and Ear, a five year-grant totaling more ... allergies (NEI Grant Number 1R01EY021798-01A1). Daniel R. Saban, ... formally entitled "Cellular and Molecular Mechanisms that Contributed to ...
... Visualize this ASU classroom: a dark green Panamanian tropical jungle. ... moves overhead so slowly that a leaf nearby spins unscathed ... poop, parrot feathers and leaf matter rain down, startling brilliant ... floor alongside six teams of students from ASU,s Herberger ...
... Research into biofuel crops such as switchgrass and ... crops and convert them into fuels. But many steps lead ... or hinder the growth of this new industry. A new ... this transition, researchers say. The model can run millions of ...
Cached Biology News:Tropical classroom inspires exhibit, Smithsonian field station design 2Tropical classroom inspires exhibit, Smithsonian field station design 3From field to biorefinery: Computer model optimizes biofuel operations 2From field to biorefinery: Computer model optimizes biofuel operations 3
...
Rabbit polyclonal to ZNF261 ( Abpromise for all tested applications). entrezGeneID: 9203 SwissProtID: Q14202...
...
sTNF-receptor I Polyclonal Antibody 100 ug affinity purified rabbit anti-human sTNF-receptor I polyclonal antibody. Performs well in WB/Elisa/Neutralization....
Biology Products: