Navigation Links
New bioengineered ears look and act like the real thing
Date:2/21/2013

his colleagues first took a combination laser scan and panoramic photo of an ear from twin girls, which provided a digitized 3D image of their ears on a computer screen. That took 30 seconds, and did not involve any ionizing radiation. The researchers then converted that image into a digitized "solid" ear and used a 3D printer to assemble a mold of the ear. The mold is like a box with a hole in the middle that is in the shape of the mirror image of the ear, say researchers.

They injected animal-derived collagen into that ear mold, and then added nearly 250 million cartilage cells. The collagen served as a scaffold upon which cartilage could grow. Collagen is the main structural protein in the body of every mammal. Animal-based collagen is frequently used for cosmetic and plastic surgery. This high-density collagen gel, which Cornell researchers developed, resembles the consistency of flexible Jell-O when the mold is removed.

"The process is fast," Dr. Bonassar says. "It takes half a day to design the mold, a day or so to print it, 30 minutes to inject the gel and we can remove the ear 15 minutes later. We trim the ear and then let it culture for several days in a nourishing cell culture medium before it is implanted."

During the three-month observation period, the cartilage in the ears grew to replace the collagen scaffold. "Eventually the bioengineered ear contains only auricular cartilage, just like a real ear," says Dr. Spector.

Previous bioengineered ears have not been able to maintain their shape or dimensions over time, and the cells within them did not survive.

The researchers are now looking at ways to expand populations of human ear cartilage cells in the laboratory so that these cells can be used in the mold.

Dr. Spector says the best time to implant a bioengineered ear on a child would be when they are about 5- or 6-years-old, because at that age, ears are 80 percent of their adult size. "We don't
'/>"/>

Contact: Lauren Woods
Law2014@med.cornell.edu
646-317-7401
Weill Cornell Medical College
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related biology technology :

1. Using 3-D printing and injectable molds, bioengineered ears look and act like the real thing
2. Graphene quantum dots: The next big small thing
3. Is Brazil the Next Big Thing in Healthcare?
4. Union Equity, Inc.s Wholly Owned Subsidiary Develops Cream that Aids in Soothing the Symptoms of Chemotherapy
5. The Law Office of Roger G. Worthington, P.C. - Longtime Supporter of the Pacific Meso Center - Donates $100,000 for Mesothelioma Research
6. Relief Organizations Worry Sandy Clothing Donations Would Start Bed Bug Epidemic; Bed Bug Removal Guide Advises Disaster Victims to Prepare for It with Bed Bug Bully
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... their baby stopped breathing, his collapsed bronchus blocking the ... Bryan Gionfriddo watched helplessly, just praying that somehow the ... said he had a good chance of not leaving ... 20-month-old son, Kaiba. "At that point, we were desperate. ... run with it." , They found hope at the ...
(Date:5/23/2013)... CASTLE ROCK, Colo. , May 23, 2013 /PRNewswire/ ... vitro diagnostic company focused on obtaining FDA clearance ... APPY1 , today announced the pricing of an underwritten ... and related warrants to purchase 3,500,000 shares of its ... share at a combined public offering price of $1.25 ...
(Date:5/23/2013)... , May 23, 2013  BioScrip, Inc. (NASDAQ: ... present at the Jefferies 2013 Global Healthcare Conference to ... New York. Richard Smith ... Hai Tran , Chief Financial Officer, will present ... Daylight Time.   About BioScrip BioScrip, ...
(Date:5/23/2013)... Baltimore, MD (PRWEB) May 23, 2013 ... time off from work motivate members of the public ... of researchers including Johns Hopkins Carey Business School ... an emphatic yes. Pointing to a large body of ... write in the May 24, 2013, issue of Science ...
Breaking Biology Technology:Baby's life saved with groundbreaking 3-D printed device that restored his breathing 2Baby's life saved with groundbreaking 3-D printed device that restored his breathing 3Venaxis Announces Pricing of Offering of Common Stock and Warrants 2Venaxis Announces Pricing of Offering of Common Stock and Warrants 3Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3
... and individuals are invited to enter the ... recognizes benefits coming from research and engineering of ... New Products Awards are given in four major ... companies (500-999 employees); medium companies (50-499 employees); and ...
... Area Technical College's Network Security Specialist degree program, ... to computer systems and data, has earned federal certification by ... . , ,It is only one of two in the ... had to match its curriculum precisely to what the NSA ...
... could be launched from Wisconsin in the next ten years, ... Committee 14-1 and could reach the Senate for a vote ... of a private spaceport in Wisconsin that would be regulated ... a Wisconsin Aerospace Authority to regulate private space travel in ...
Cached Biology Technology:Space port could open in Sheboygan in next 10 years 2Space port could open in Sheboygan in next 10 years 3
(Date:5/23/2013)... carrying more than 284 million tons of cargo, transit the ... toll fees for the Panama Canal Authority. Each time a ... are used from Gatun Lake, which is also a source ... isthmus. , However, the advent of very large "super" ... at sea, has demanded change. The Panama Canal is being ...
(Date:5/23/2013)... wrapping of genomic DNA around nucleosomes in the ... A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now ... be locally displaced from nucleosomes for transcription. , ... in the cell nucleus, wrapped around disk-shaped particles ... four different histone proteins and accommodating two loops ...
(Date:5/23/2013)... A new report from the Institute of Medicine ... in at least 60 minutes of vigorous or moderate ... than half of American youth meet current evidence-based guidelines ... intensity physical activity daily, according to the report, which ... school for nearly half of their waking hours, the ...
Breaking Biology News(10 mins):Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3Biochemistry: Unspooling DNA from nucleosomal disks 2Schools should provide students with daily physical activity, IOM recommends 2
... suggest that past climate changes and sea level fluctuations may ... region of South America. Today, the Amazon basin ... yet the reasons why this came to be are not ... three species of leafcutter ants from Central and South America ...
... of the most pressing international issuessuch as renewable energy ... pressing than ever that an informed public be capable ... The Ecological Society of America (ESA),s 93rd Annual Meeting, ... importance of using a broad range of tools to ...
... of Texas at Austin is part of a team ... the water desalination process, increasing access to fresh water ... the desalination process more efficient with better membranes, it ... water, which will expand the availability of clean water ...
Cached Biology News:Study suggests past climate changes may have promoted the formation of new species in the Amazon 2Training future scientists at the Ecological Society of America's 93rd Annual Meeting 2New chlorine-tolerant, desalination membrane hopes to boost access to clean water 2
A431 cells stimulated with EGF Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Peptide-affinity Purified Polyclonal Antibody to Olfactory Receptor, Family 2, Subfamily H, Member 3...
Molecular Biological Resources offers bulk quantities of existing protein products. Please see the Chimerx divisions website for existing products and contact lloconne@molbiores.com for pricing....
... from balances and scales with RS232 ports and ... If you can type the weight into the ... Simple to use parser extracts required data ... user information , Collect data at timed intervals ...
Biology Products: