During model development, MetaFlux will identify the subset of biomass metabolites (end products of biosynthesis) that cannot currently be produced. The software also paints reaction flux rates onto an automatically generated organism-specific metabolic map diagram, much like an online road map shows traffic flow rates.
MetaFlux is part of Pathway Tools, available freely to academic users and for a fee to commercial users. An article describing MetaFlux is in the online edition of the journal Bioinformatics at http://oxford.ly/metaflux, and will appear in the journal's 3rd issue of 2012, which publishes in early February.
The project described was supported by Award Number R01GM080746 from the National Institute of General Medical Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of General Medical Sciences or the National Institutes of Health.
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