Navigation Links
Neural prosthesis restores behavior after brain injury
Date:12/9/2013

Scientists from Case Western Reserve University and University of Kansas Medical Center have restored behaviorin this case, the ability to reach through a narrow opening and grasp foodusing a neural prosthesis in a rat model of brain injury.

Ultimately, the team hopes to develop a device that rapidly and substantially improves function after brain injury in humans. There is no such commercial treatment for the 1.5 million Americans, including soldiers in Afghanistan and Iraq, who suffer traumatic brain injuries (TBI), or the nearly 800,000 stroke victims who suffer weakness or paralysis in the United States, annually.

The prosthesis, called a brain-machine-brain interface, is a closed-loop microelectronic system. It records signals from one part of the brain, processes them in real time, and then bridges the injury by stimulating a second part of the brain that had lost connectivity.

Their work is published online this week in the science journal Proceedings of the National Academy of Sciences.

"If you use the device to couple activity from one part of the brain to another, is it possible to induce recovery from TBI? That's the core of this investigation," said Pedram Mohseni, professor of electrical engineering and computer science at Case Western Reserve, who built the brain prosthesis.

"We found that, yes, it is possible to use a closed-loop neural prosthesis to facilitate repair of a brain injury," he said.

The researchers tested the prosthesis in a rat model of brain injury in the laboratory of Randolph J. Nudo, professor of molecular and integrative physiology at the University of Kansas. Nudo mapped the rat's brain and developed the model in which anterior and posterior parts of the brain that control the rat's forelimbs are disconnected.

Atop each animal's head, the brain-machine-brain interface is a microchip on a circuit board smaller than a quarter connected to microelectrodes impl
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
2. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
3. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
4. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
5. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
6. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
7. Triangles guide the way for live neural circuits in a dish
8. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
9. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
10. Neuralstem President And CEO To Present At The 2012 Rodman & Renshaw Annual Healthcare Conference
11. Neuralstem Cells Induce Significant Functional Improvement In Permanent Rat Spinal Cord Injury, Cell Study Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... 2014 The Asian arthroscopic devices report ... analysis and forecast of revenue. The arthroscopic devices market ... by 2018, at a CAGR of 6.5% from 2013 ... Asian arthroscopic devices market, to get an idea of ... of the segmentation of arthroscopic devices market in the ...
(Date:10/18/2014)... According to a new market research report “Hydraulic ... Trends & Forecasts up till 2017”, hydraulic fracturing market ... value is expected to increase from $40 billion in ... during the same period. North America is expected to ... of hydraulic horse power supplied by the year 2011. ...
(Date:10/17/2014)... SAN DIEGO and HILDEN, ...   , Translational research ... new capabilities being presented at the American Society ... Volume of 250,000-plus DNA samples linked to Ingenuity ... superior depth for genomic analysis  Ingenuity ...
(Date:10/17/2014)... (PRWEB) October 17, 2014 The Europe ... additives market in Europe with analysis and forecast of ... Fuel Additives Market report, to get an idea of ... of the segmentation in the European fuel additives market, ... , http://www.micromarketmonitor.com/market/europe-fuel-additives-5379768082.html , Fuel additives are chemicals ...
Breaking Biology Technology:The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 2The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 3The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 4
... Scheduled for Thursday, May 1, 2003 at the Midwest ... about addressing the commonchallenges of migrating Microsoft Windows NT(R) ... 2003 family delivers a connected, scalable,reliable platform that has ... solve complex IT infrastructure problems. , , ,"We ...
... the Midwest. Only five of these types of facilities exist ... Terrence R. Dolan, PhD, Director of the Fitchburg Technology Campus. ... factory will be an engine for Wisconsins biotechnology industry. Sources ... list of global clients who are eagerly awaiting its start-up. ...
... any good entrepreneur will tell you that every opportunity is ... weve received about 1,500 applications for financing, performed about 750 ... or facilitated more than a dozen investments (and a couple ... a final reminder of why were doing this in the ...
Cached Biology Technology:Biotech Manufacturing Facility to be Built in Wisconsin 2"For Angels Only...When to say No... 2"For Angels Only...When to say No... 3
(Date:10/19/2014)... Improving household electricity access in India over the ... nation,s total carbon emissions growth during that time, ... journal Nature Climate Change ., "Energy access ... all aspects of life, including education, communication, and ... the study. , While increased energy access is ...
(Date:10/18/2014)... October 2014 Psychological stress and stress-related psychiatric disorders ... diseases, but the molecular mechanisms underlying this ... contribute to the development of targeted preventive ... these devastating diseases. This work is presented ... in Berlin., Now an international group of ...
(Date:10/18/2014)... Among a group of 2,000 patients referred for ... a potential molecular diagnosis for 25 percent, including ... and new mutations contributing to disease, according to ... study is being released to coincide with the ... Whole-exome sequencing analyzes the exons or coding regions ...
Breaking Biology News(10 mins):Improved electricity access has little impact on climate change 2Researchers find why depression and aging linked to increased disease risk 2Whole-exome sequencing shows potential as diagnostic tool 2
... plants, animals, and microbes introduced to regions beyond their ... $1.4 trillion dollars . They are responsible for the loss ... uptick in infectious diseases. Not all non-native species pose ... several decades teasing apart the conditions that set the stage ...
... posed to people who work with tiny fibres used in ... Research into the health risks posed by nanofibres used ... has pinpointed the lengths at which these fibres are harmful ... a range of materials including carbon, are about 1,000 times ...
... salt sea without an outlet, lies over 400 meters ... because it increases their buoyancy. "For scientists, however, ... a diachronic view of its climate past," says Prof. ... and Paleontology at the University of Bonn. ...
Cached Biology News:Losing stream in our battle to predict and prevent invasive species 2Losing stream in our battle to predict and prevent invasive species 3Drastic desertification 2Drastic desertification 3
...
Antibody specific for trimethyl-Lys27 of histone H3. Mouse monoclonal. Antigen: Synthetic peptide derived from histone H3, trimethylated at lysine 27...
DL-Dithiothreitol (Clelands Reagent) ,PROTEASE FREE!! ,Molecular Biology Grade ,PRODUCT MUST SHIP NEXT DAY DURING HOT SUMMER MONTHS. ,C 4 H 10 O 2 S 2 ,Molecular Weight: 154.25 ,CAS RN: [27565-...
DTT 50 l...
Biology Products: