Navigation Links
NIH grants $750,000 to develop device to determine temperature of neonate's brain
Date:9/2/2007

NORFOLK, Va. -- A neonatologist at Childrens Hospital of The Kings Daughters (CHKD) is leading the clinical trials of a $750,000 study funded Friday, Aug. 31, to develop a device to measure the precise temperature of a newborns brain.

The National Institutes of Health (NIH) grant stems from recent studies showing that cooling of the brain of oxygen-starved newborns dramatically reduces the incidence of Cerebral Palsy, other neurological damage, and death.

While recent studies have demonstrated the effectiveness of the brain-cooling regimen, doctors dont yet have a precise way to measure the brains temperature. The NIH grant will allow researchers to adapt a non-invasive radiometric-sensing device -- developed by Meridian Medical Systems of Woolwich, ME -- to provide precise temperatures of brain tissue beneath the skull.

Precise brain temperature measurements are essential to maximize the benefit of therapeutic hypothermia, said Thomas Bass, M.D., a neonatologist at CHKD, the pediatric teaching hospital of Eastern Virginia Medical School (EVMS) in Norfolk, VA. Bass is also an EVMS professor of pediatrics.

About two to three in 1,000 newborns born at term are at risk of brain damage from oxygen-deprivation during birth. About half of the infants born with the condition will die or suffer severe handicaps such as mental retardation or cerebral palsy.

Historically, doctors tended to keep newborns warm, at incubator-like temperatures, and treated the hypoxic infants with medicine. But several recent studies have demonstrated that cooling the brain can significantly reduce both death and severe disability.

Injury from oxygen-deprivation continues long after delivery, said Bass, co-investigator of a groundbreaking study on the subject published in Pediatric Neurology in 2005. Cooling the brain decreases its need for oxygen and can slow or stop continuing damage.

Doctors today often cool the brain using whole-body cooling blankets or specially developed cooling caps. The goal of the therapy is to reduce the brain temperature by about four degrees centigrade. While cooling therapy has become more common, doctors must extrapolate the brains temperature by using a rectal thermometer. The rectal temperature can be off by as much as two degrees.

Thats not acceptable, said Bass.

Under the NIH grant, Bass, Meridian and a team of EVMS research scientists will exploit the fact that all human tissue emits energy at microwave frequencies. Those emissions can travel through tissue, but only for a few millimeters, depending on the frequency. As the tissues temperature rises, emissions increase.

By tabulating the frequency and strength of electromagnetic emissions emanating from the body, Meridian has developed a device that can measure the temperature of tissue a given distance below the skins surface, even through a babys skull.

The research team hopes to use this technology to develop a small, lightweight device that can be affixed to an infants head to detect electromagnetic emissions generated 15 millimeters below the surface, giving doctors the exact temperature of the childs brain.


'/>"/>
Contact: Greg Raver-Lampman
Greg.Lampman@CHKD.org
757-668-7554
Children's Hospital of The King's Daughters
Source:Eurekalert

Related biology technology :

1. State to offer $850K in high-tech training grants
2. Grants worth $800,000 help BellBrook Labs develop products
3. Venture-backed firms could become eligible for federal SBIR grants
4. Mithridion wins grants for Alzheimers research
5. NASDAQ grants Merge more time for compliance
6. Morgridge seed grants attract over 220 proposals
7. Medical College researchers win federal grants
8. NSF grants bolster integrative graduate study at UW-Madison
9. Three state businesses receive technology grants
10. SBC Foundation awards technology grants in Wisconsin
11. Visonex plans to expand with state grants, loan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... Vancouver, BC, Canada (PRWEB) , ... July 20, 2017 , ... ... today announced the winning recipients of the 2017 IAC Awards at the 22nd ... IAC awards, the committee also named four faculty to receive the Distinguished Fellowship Awards. ...
(Date:7/20/2017)... ... ... Corporate Directors Forum is recognizing six San Diego directors for their extraordinary ... The awards will be presented Thursday, September 7th, from 6 to 9 p.m. at ... significantly positive contributions in the boardrooms of some of our region’s most respected and ...
(Date:7/18/2017)... ... July 18, 2017 , ... G-CON ... Patent and Trademark Office for its Patent Applications 14/858,857 and 13/669,785 both entitled ... these patent applications further expand the protection of G-CON’s R&D investments and validate ...
(Date:7/17/2017)... ... July 17, 2017 , ... The Academy of Model Aeronautics (AMA) ... Model Aviation Day will take place from 9 a.m. to 2 p.m. at the ... for all ages. , Aviation Adventure Day will be packed with entertaining activities for ...
Breaking Biology Technology:
(Date:4/17/2017)... 17, 2017 NXT-ID, Inc. (NASDAQ: NXTD ... filing of its 2016 Annual Report on Form 10-K on Thursday ... ... available in the Investor Relations section of the Company,s website at ... website at http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
Breaking Biology News(10 mins):