Navigation Links
Molecular machine could hold key to more efficient manufacturing
Date:1/10/2013

An industrial revolution on a minute scale is taking place in laboratories at The University of Manchester with the development of a highly complex machine that mimics how molecules are made in nature.

The artificial molecular machine developed by Professor David Leigh FRS and his team in the School of Chemistry is the most advanced molecular machine of its type in the world. Its development has been published in the journal Science.

Professor Leigh explains: "The development of this machine which uses molecules to make molecules in a synthetic process is similar to the robotic assembly line in car plants. Such machines could ultimately lead to the process of making molecules becoming much more efficient and cost effective. This will benefit all sorts of manufacturing areas as many manmade products begin at a molecular level. For example, we're currently modifying our machine to make drugs such as penicillin."

The machine is just a few nanometres long (a few millionths of a millimetre) and can only be seen using special instruments. Its creation was inspired by natural complex molecular factories where information from DNA is used to programme the linking of molecular building blocks in the correct order. The most extraordinary of these factories is the ribosome, a massive molecular machine found in all living cells.

Professor Leigh's machine is based on the ribosome. It features a functionalized nanometre-sized ring that moves along a molecular track, picking up building blocks located on the path and connecting them together in a specific order to synthesize the desired new molecule.

First the ring is threaded onto a molecular strand using copper ions to direct the assembly process. Then a "reactive arm" is attached to the rest of the machine and it starts to operate. The ring moves up and down the strand until its path is blocked by a bulky group. The reactive arm then detaches the obstruction from the
'/>"/>

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Scientists design, control movements of molecular motor
2. Study identifies targeted molecular therapy for untreatable NF1 tumors
3. Caris Sponsors CancerCare Connect Education Workshop on Molecular Profiling in the Treatment of Breast Cancer
4. Karmanos Cancer Center first in Midwest to offer latest Molecular Breast Imaging
5. Caris Life Sciences mejora la evaluación por perfil molecular con los biomarcadores ROS1 y MGMT-metilación
6. Caris Life Sciences Enhances Molecular Profiling Service with Addition of ROS1 and MGMT-Methylation Biomarkers
7. A firm molecular handshake needed for hearing and balance
8. USC Center For Applied Molecular Medicine To Honor Sumner Redstone And Murray Gell-Mann, Ph.D. At The Inaugural REBELS WITH A CAUSE Gala
9. Merrimack Pharmaceuticals To Present Preliminary Clinical Data For Novel Therapies Targeting Molecular Pathways In Advanced Cancers
10. Indian Pharma MNC Piramal Investing in German Molecular Imaging Technology
11. Spectrometry Market (Atomic, Molecular and Mass Spectrometry) - Global Scenario, Trends, Industry Analysis, Size, Share & Forecast 2011 - 2017
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... (PRWEB) January 15, 2014 2013 was ... Scottsdale’s Brain State Technologies®. They saw continued independent research ... Center who were awarded a $1 million grant from ... in “Brain and Behavior” a peer reviewed journal, Amy ...
(Date:1/14/2014)... Doylestown, PA (PRWEB) January 14, 2014 Date: ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, Warrington, ... only national nonprofit organization solely dedicated to finding a cure ... those affected worldwide, will host its annual Crystal Ball on ...
(Date:1/14/2014)... As pet owners drew up their lists of New Year,s ... better care of my furry companion." Nowadays there are pet salons, ... cases to take the little canine or feline darlings along wherever ... buy some pricey toys at the pet store. But anyone who ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management ... Product Strategy. In this role, Michelle will work with current ... in the development of iLab products. Her main goal will ... to the scientific community by offering the most advanced, user-friendly, ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... - GeneNews Limited (TSX: GEN), a company focused on ... diseases and personalized health management, today announced that it ... being held at the Sheraton Centre in Toronto from ... booth # 400, will feature the Company,s lead product, ...
... and CAMBRIDGE, England, November 26 Sosei,Group Corporation ("Sosei"; ... it has out-licensed its IP and Know How,relating to ... a,Cambridge, UK based pharma company, for the treatment and ... Mefloquine is a highly efficacious anti-malarial drug that is ...
... CAS REGISTRY, the world,s most,authoritative collection of disclosed chemical ... CAS Registry Number(R),1073662-18-6 recently was assigned to an azulenobenzofuran ... http://www.newscom.com/cgi-bin/prnh/20081125/CLTU095 ) , ... The 40 millionth substance ...
Cached Biology Technology:GeneNews to exhibit ColonSentry(TM) at Family Medicine Forum 2008 2Sosei Announces the Out-licensing of RS(+) Mefloquine to Treague Ltd for the Treatment and Prophylaxis of Malaria 2CAS Registers 40 Millionth Substance in CAS REGISTRY(SM) 2
(Date:4/23/2014)... other chronic inflammatory disorders among people of lower socioeconomic ... exposure to the microbes that thrive in rural environments, ... published in the journal Clinical & Experimental Immunology ... have less access to green spaces may be more ... immune system dysfunction. , When our immune systems are ...
(Date:4/23/2014)... most in their mid-thirties and forties, face a ... within two decades. "Mutant" protein clusters, long blamed ... been the primary focus of therapies in development ... from Prof. Gerardo Lederkremer and Dr. Julia Leitman ... and Immunology, in collaboration with Prof. Ulrich Hartl ...
(Date:4/23/2014)... Valley, NY. (Apr. 23, 2014) People who have ... potential to restore neurological function. However, a study conducted ... issue of Cell Transplantation , but is currently ... http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-ct1168Chen , has found that when one group ... cells (PBSCs) injected directly into the brain and a ...
Breaking Biology News(10 mins):Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3On the defensive 2On the defensive 3Autologous stem cell therapy improves motor function in chronic stroke victims 2
... relocation of an Inuit village already underway, some 400 ... in Alaska for a UN-affiliated conference April 20-24 to ... to both mitigate and adapt to climate change. ... Global Summit on Climate Change is also designed to ...
... Biology 2009 meeting in New Orleans, Dr. Kristine ... Control Technologies Branch of the Health Effects Laboratory ... results from the first study to directly link ... with exposure to different vibration frequencies with biological ...
... grew warmer from 18,700 to 10,000 years ago, juniper trees ... of their favorite food. Now, University of Utah biologists have ... eat toxic creosote bushes that replaced juniper. "It was ... Dearing, senior author of the study, published online Tuesday, April ...
Cached Biology News:Indigenous peoples at world summit to share climate change observations, coping techniques 2Indigenous peoples at world summit to share climate change observations, coping techniques 3Indigenous peoples at world summit to share climate change observations, coping techniques 4Indigenous peoples at world summit to share climate change observations, coping techniques 5Indigenous peoples at world summit to share climate change observations, coping techniques 6Risk of vibration-induced vascular injuries linked to vibration frequency differences 2Poison: It's what's for dinner 2Poison: It's what's for dinner 3Poison: It's what's for dinner 4Poison: It's what's for dinner 5
... HistoMark Biotin Streptavidin-HRP Systems provide ... and intracellular antigens in frozen or ... These systems also facilitate double ... can be performed simultaneously with primary ...
...
... Polystyrene covers can be used ... Ridged covers for stacking of ... covers for use with automated ... ridged and non-ridged, are available ...
... Versatile, modular, computer controlled pre-amplifier suitable for ... isolated electrode input for recording physiological signal ... and a transducer input for use with ... transducers. Additional options include a stimulus artefact ...
Biology Products: