Navigation Links
'Micro shuttle' drug delivery could mean an end to regular dosing
Date:10/1/2009

Scientists working at Queen Mary, University of London, have developed micrometer-sized capsules to safely deliver drugs inside living cells.

In the future, this technique could allow full courses of prescription drugs to be effectively 'shrink-wrapped' and buried under the skin or inside the body.

These "micro shuttles" can be loaded with a specific dose of medication and be opened remotely, releasing their contents.

Using this new technique, drugs - like insulin for managing diabetes - could be implanted inside the body for use when they are needed. Their release could then be prompted by a biological trigger like a drop in blood sugar levels, or activated manually with a pulse of light.

PhD student Matthieu Bdard and Prof Gleb Sukhorukov of Queen Mary's School of Engineering and Materials Science have proved this new technique to work in living tissue by delivering fluorescent test-molecules in light-activated capsules.

The work is in partnership with Dr Sebastian Springer at Jacobs University in Bremen and colleagues from the Max Plank Institute of Colloids. The findings are reported in the October issue of Small (DOI: 10.1002/smll.200900809).

Matthieu Bdard said: "The main advantage of using such microcapsules is that they can be designed to be very stable inside the body, protecting their contents. This is particularly important for the many medications that are rapidly degraded or altered by the body. These capsules can be used to 'store' drugs in the body for later use."

The capsules, which have a diameter of two micrometers (about the size of a bacterium), are built by wrapping strands of a metabolism-resistant material around spherical particles, which are then dissolved in acid, leaving behind an empty container.

To fill the capsules, the scientists heat them in a solution that contains the desired drug compound. This makes them shrink and traps some of the solution and co
'/>"/>

Contact: Simon Levey
s.levey@qmul.ac.uk
44-020-788-25404
Queen Mary, University of London
Source:Eurekalert

Page: 1 2

Related biology technology :

1. BioMaxx Systems Inc. Signs Engagement Letter With Alcofuel Technologies for Provision of an Ethanol Micro-Refinery
2. SportCoatings; The North American Booster Club Association (NABCA); the Coatings Specialist Group New Booster Program Goes High Tech With Invisible Antimicrobial Defense
3. Microchip Biotechnologies, Inc. Secures Exclusive License to Use New University of Alberta Technology for Developing Microfluidic Devices
4. Micromet, Inc. to Present at the Sal. Oppenheim 2nd European Healthcare Conference
5. Microfluidic chambers advance the science of growing neurons
6. Quick microchip test for dangerous antibiotic resistant bacteria
7. GenoLogics Geneus Achieves GeneChip-compatible(TM) Status with the Affymetrix GeneChip(R) Microarray Platform
8. NYU Medical Center Collaborates With Rosetta Genomics to Develop a microRNA-Based Diagnostic Test for Melanoma
9. CeloNova BioSciences Announces Worlds First Line of Fully Color-Coded Embolic Particles at CIRSE: Embozene(TM) Color-Advanced Microspheres
10. New DNA-based technique for assembly of nano- and micro-sized particles
11. Microbia and Forest Laboratories Announce Linaclotide Co-Development and Co-Marketing Collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... RBJ today announces the firm brokered a long-term lease totaling ... biopharmaceutical company, at Two Ledgemont Center in Lexington, ... president, and Brian Cohen , senior vice president, represented ... 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... 2015 Protocol Networks brings independent technology ... of brand-neutral, independent consultants, Protocol Networks has recently announced ... over the years, his company has attracted several clients ... Plainfield, as well as others. With the success of ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Controlled Substance ... Alliance, which helps companies check the legal requirements around ... expand to China. , As their international operations ... globally adopting software solutions built as a result of ...
(Date:1/22/2015)... 2015  Varian Medical Systems (NYSE: VAR ), world ... its commitment to sustainability with inclusion on a prestigious list ... ranked healthcare equipment company among the Corporate Knights Global 100 ... Forum at Davos, Switzerland . ...
Breaking Biology Technology:Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Global Compliance Service for Controlled Substances to Expand to China 2Varian Honored Among World's 100 Most Sustainable Corporations 2
... Chang-Hwan Choi of the Department of Mechanical Engineering at ... of the 2010 Young Investigator Program (YIP) award by ... academic scientists and engineers who show exceptional promise for ... of young outstanding scientists and engineers," said ONR,s Director ...
... ShowPatrol ... the specific requirements and challenges of the search industry. , ... Cheshire, CT (PRWEB) April 8, 2010 -- ShowPatrol will ... ShowPatrol is responsible for all sales and marketing of the CardBrowser service to search firms ...
... ... and experience in the life sciences industry and academia to the pioneering life sciences ... ... sciences tool company which introduced the world,s first 3D biosensor surface for label-free biomolecular ...
Cached Biology Technology:Dr. Chang-Hwan Choi honored with prestigious Young Investigator Award 2Dr. Chang-Hwan Choi honored with prestigious Young Investigator Award 3Danny Cahill announces new company ShowPatrol has partnered with CardBrowser 2Silicon Kinetics Announces Addition of Dr. Rick Brown and Dr. Eric Topol to Its Board of Directors 2Silicon Kinetics Announces Addition of Dr. Rick Brown and Dr. Eric Topol to Its Board of Directors 3
(Date:12/22/2014)... 2014  The 2014 Holiday Season may be the brightest ... reports that the long anticipated floodgates for consumer biometrics ... for smart phones, tablets, and wearable mobile devices that ... billion users with nearly 4.8 billion biometric devices by ...
(Date:12/17/2014)... 15, 2014 Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ... Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology ... http://photos.prnewswire.com/prnh/20130307/600769 Based on a ... introduces for the first time a fingerprint sensor in ...
(Date:12/17/2014)... fundamentally transforming the travel experience and nowhere is this ... decade, ePassports, biometric readers, and secure document scanners have ... via eGates and Automated Passport Control (APC) Kiosks at ... across the globe. According to ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... Institute have developed a new method for studying the complex ... less studied spreader of human malaria. An. albimanus ... in humans in South America and regions outside of Africa. ... An. albimanus mosquito has not been sequenced and since ...
... will take on the challenge of providing the first insights ... will work with scientists from the John Innes Centre on ... the Royal Society and 2000 from the British Society for ... reduce losses to Take-all, one of the most serious fungal ...
... model suggests that inhospitable hydrodgen-sulphide rich waters could have ... oceans. The research, published online this week in the ... the oceans 550-700 million years ago and shows that ... of complex life, were controlled by the biological availability ...
Cached Biology News:New method for researching understudied malaria-spreading mosquitoes 2Growing talent -- schools to provide vital knowledge for food security 2Toxic oceans may have delayed spread of complex life 2
Porcine Aortic Endothelial Cells (PAOEC) (>500,000 cells)...
alpha-N-Catenin Antibody Shipping Temperature: HOT Storage Temperature: -20C...
... Mouse monoclonal [E12] to MAP1 Light Chain ... mediate the physical interactions between microtubules and components ... of a heavy chain subunit and multiple light ... is one of the light chain subunits and ...
... as smooth muscle cell specific protein, is reported ... tissues such as intestine, lung and uterus. It ... SM22 alpha expression has been reported in most ... and visceral forms. It is also reported to ...
Biology Products: