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Metabolic Pathways Collection at SRI International the Largest in the World
Date:4/24/2013

ividual laboratories in individual publications into pathways that were not previously recognized by those researchers.  For example, the pathway for 3-phosphoinositide degradation was assembled from studies by several different laboratories that characterized the individual reactions and enzymes within the pathway.

MetaCyc, one of the databases in SRI's BioCyc database collection, is a free online reference source used by thousands of researchers in government, academia, and industry.  Scientists use MetaCyc to predict biochemical pathways that are present in a newly sequenced organism and to better understand where in the metabolic network a particular gene or metabolite of interest is involved. This view inside of a cell can help in a range of applications, especially metabolic engineering, where cells are manipulated to produce a specific substance, such as antibiotics or biofuels. It is also helpful for understanding how to degrade particular compounds, such as pesticides or chemicals released after an oil spill.

SRI International research was funded by grant GM080746 from the NIH National Institute of General Medical Sciences and by grant DE-SC0004878 from the Department of Energy.

Contribution from Carnegie Institution was funded by grants IOS-1026003 and DBI-0640769 from the National Science Foundation.

About SRI International
Innovations from SRI International have created new industries, billions of dollars of marketplace value, and lasting benefits to society—touching our lives every day. SRI, a nonprofit research and development institute based in Silicon Valley, brings its innovations to the marketplace through technology licensing, new products, and spin-off ventures. Government and business clients come to SRI for pioneering R&D and solutions in computing and communications, chemistry and materials, education, energy, health and pharmaceuticals, national defense, robotics, sens
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