Navigation Links
MammaPrint(R) Breast Cancer Test Validated in Lymph Node-Positive Breast Cancer Patients
Date:12/13/2007

Results to be presented at San Antonio Breast Cancer Symposium

AMSTERDAM, Netherlands, Dec. 13 /PRNewswire/ -- Agendia BV, world leader in the rapidly evolving field of molecular diagnostics, announced today that an independent international consortium has demonstrated the prognostic power of its MammaPrint(R) breast cancer prognosis test in patients who have 1-3 positive lymph nodes. The data show that MammaPrint(R) can accurately identify a low risk group of lymph node-positive breast cancer patients with an excellent survival, implications that will help doctors to decide the optimal treatment management.

"Lymph node status is considered to be one of the most powerful prognostic factors for operable breast cancer, with a direct relationship between the number of positive nodes and disease outcome. However, approximately 30% of lymph node-positive patients will remain free of distant metastases without adjuvant chemotherapy," said Dr Laura van 't Veer, chief research officer at Agendia, who participated in the study. "Identifying patients with lymph node-positive disease who are at low risk of recurrence might lead to changes in guidelines for adjuvant chemotherapy."

In the current study, 241 tumor samples from breast cancer patients with 1-3 positive lymph nodes at 2 hospitals were selected and analyzed by the international TRANSBIG consortium. Patients that were classified as "high risk" for recurrence using MammaPrint(R) had significantly worse 5- and 10-year survival rates than those that were identified as "low risk." The numbers indicate that MammaPrint(R) has excellent prognostic power, even in patients having 1-3 positive lymph nodes. The entire study will be presented as an oral presentation at the San Antonio Breast Cancer Symposium on Thursday, December 13 in San Antonio, TX, USA.

"This study is in excellent agreement with our 2002 publication in the New England Journal of Medicine in which we also found that MammaP
'/>"/>

SOURCE Agendia BV
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. GlaxoSmithKline Recognizes University of Michigans Dr. Daniel F. Hayes as the First Recipient of the Gianni Bonadonna Breast Cancer Award
3. Imaging Diagnostic Systems New Laser Breast Imaging Scanner Introduced in Malaysia
4. NeoMatrix Announces Additional Funding for Breakthrough Breast Cancer Screening Test
5. Largest Asian Cancer Hospital to Evaluate New CT Laser Breast Imaging System
6. Cellumen Establishes Collaboration in Breast Cancer Patient Stratification
7. Celebrities and Notables From the Worlds of Film, Television, Music and Sports Join Lifetime Televisions 13th Annual Multi-Platform Stop Breast Cancer For Life Campaign
8. Agendia Acquires Rights to the Discovery of a Major Drug Resistance Mechanism in Breast Cancer Potentially Leading to a Herceptin(R) Sensitivity Test
9. FDA Approves IXEMPRA(TM) (ixabepilone), a Semi-Synthetic Analog of Epothilone B, for the Treatment of Advanced Breast Cancer
10. Panacea Pharmaceuticals Announces the Availability of BC Detect(SM), a Serum- Based Diagnostic Test for Breast Cancer
11. Agencourt Genomic Services is Key Collaborator in New Research That Further Defines Landscape of Breast and Colon Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 18, 2014 ... ) has announced the addition of ... Strategic Business Report" report to ... report analyzes the worldwide markets for ... the following Product Segments: Polymeric Materials, ...
(Date:9/18/2014)... Washington, D.C. (PRWEB) September 18, 2014 ... Dick Durbin and Sen. Jim Risch for National Lab ... research projects from across the national laboratory system. Durbin ... Caucus, which aims to increase awareness of the reach ... breakthrough technologies and discoveries to address some of our ...
(Date:9/18/2014)... , Sept. 18, 2014 Research ... the "Global N-acetylcysteine Industry Report 2014" ... Global N-acetylcysteine Industry Report 2014 is a professional ... the global N-acetylcysteine industry. The report ... definitions, classifications, applications and industry chain structure. The ...
(Date:9/18/2014)... 2014 Research and Markets has ... (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends ... The global companion diagnostics market is ... 2014 to 2019. Factors such as rising need for ... diagnostics by the pharmaceutical industry, support from regulatory authorities, ...
Breaking Biology Technology:Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3Global N-acetylcysteine Industry Report 2014 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 3
... Oramed Pharmaceuticals Inc. (OTCBB: ORMP.OB) ( http://www.oramed.com ... today that its work entitled "Evaluation of the Safety ... Volunteers" will be presented at the Eleventh Annual Meeting ... San Francisco, California. "The selection of Oramed ...
... 25, 2011 Reportlinker.com announces that a ... its catalogue: Global Automated ... http://www.reportlinker.com/p092467/Global-Automated-And-Rapid-Microbiological-Tests-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=In_Vitro_Diagnostic This ... and Rapid Microbiological Tests in US$ Million ...
... some patients develop a potentially deadly blood infection from ... bodies have gene mutations that allow them to stick ... infections because of a biofilm of persistent bacterial bugs ... some strains of the bacteria, Staphylococcus aureus, have just ...
Cached Biology Technology:Oramed Pharmaceuticals Chosen to Present at the Diabetes Technology Meeting (October 27-29, 2011; San Francisco, CA) 2Global Automated And Rapid Microbiological Tests Industry 2Global Automated And Rapid Microbiological Tests Industry 3Global Automated And Rapid Microbiological Tests Industry 4Global Automated And Rapid Microbiological Tests Industry 5Global Automated And Rapid Microbiological Tests Industry 6Global Automated And Rapid Microbiological Tests Industry 7Global Automated And Rapid Microbiological Tests Industry 8Global Automated And Rapid Microbiological Tests Industry 9Global Automated And Rapid Microbiological Tests Industry 10Global Automated And Rapid Microbiological Tests Industry 11Global Automated And Rapid Microbiological Tests Industry 12Global Automated And Rapid Microbiological Tests Industry 13Global Automated And Rapid Microbiological Tests Industry 14Global Automated And Rapid Microbiological Tests Industry 15Global Automated And Rapid Microbiological Tests Industry 16Global Automated And Rapid Microbiological Tests Industry 17Global Automated And Rapid Microbiological Tests Industry 18Global Automated And Rapid Microbiological Tests Industry 19Global Automated And Rapid Microbiological Tests Industry 20Global Automated And Rapid Microbiological Tests Industry 21Global Automated And Rapid Microbiological Tests Industry 22Global Automated And Rapid Microbiological Tests Industry 23Global Automated And Rapid Microbiological Tests Industry 24Global Automated And Rapid Microbiological Tests Industry 25Global Automated And Rapid Microbiological Tests Industry 26Study offers clues as to why some patients get infections from cardiac implants 2Study offers clues as to why some patients get infections from cardiac implants 3Study offers clues as to why some patients get infections from cardiac implants 4Study offers clues as to why some patients get infections from cardiac implants 5
(Date:9/18/2014)... tonight at the third annual Golden Goose Award ceremony ... infants and in paving the way for the telecommunications ... by the National Science Foundation, the National Institutes of ... honored at a ceremony at the Library of Congress ... Congress will be on hand to help present their ...
(Date:9/18/2014)... of the fish world, are the ideal animal in ... They,ve moved from the ocean into tens of thousands ... time changing their skeleton to adapt to the new ... of sticklebacks now have turned up one of the ... simple change in that gene,s regulation in a freshwater ...
(Date:9/17/2014)... were instrumental in the creation of the Santa Ana ... the fire threat potential of the powerful, hot, dry ... an inferno. The index was introduced Sept. 17 by ... San Diego Gas and Electric. , The index includes ... will be used to help fire agencies and other ...
Breaking Biology News(10 mins):3rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2
... December 12, 2012 Cell aging, or cellular senescence, ... to tumor development. Activated oncogenes are able to induce ... (OIS) could play a key role in future cancer ... in the regulation of OIS. This study is published ...
... plant dye once prized throughout the Old World to make fiery ... for a new "green" battery. Chemists from The ... and the U.S. Army Research Laboratory to develop a non-toxic and ... roots of the madder plant ( Rubia species). More ...
... engineering researchers at Rensselaer Polytechnic Institute shows, for the ... significant role in the strength of our bones. The ... fighting osteoporosis and lowering the risk of bone fracture. ... the study details how fractures in healthy bones begin ...
Cached Biology News:Previously unknown mechanism identified in oncogene-induced senescence 2Ancient red dye powers new 'green' battery 2Ancient red dye powers new 'green' battery 3Battling brittle bones... with broccoli and spinach? 2
... DIGIVIEW line of digital x-ray detectors from ... device complete with 12 to 16 bit ... of a photodiode array sensor with pixel ... are available in low x-ray energies (10-50 ...
The Odyssey Infrared Imaging System is a complete family of products that includes the Odyssey Imager, IRDye labeling reagents and Odyssey software for scan control and data analysis....
... System from KUBTEC is a dual capability system ... dimensional representation of the specimen under test. While ... X-ray images, the micro focus source also allows ... in standard 2D images. The 50 mm x ...
... the condition in which a lack of ... the various antioxidants. Oxidative stress appears ... several diseases, including artherosclerosis, chronic inflammatory diseases, ... antioxidant systems that are very important for ...
Biology Products: