Navigation Links
Major disease-vector mosquito reveals the secrets of its immune system
Date:10/1/2010

by Professor Marc Muskavitch from Boston College, the Broad Institute, and Harvard School of Public Health, examined the responses of each mosquito species to different pathogens including parasites, viruses, bacteria, and worms, to identify genes that play a role in mosquito immune defences."Our pathogenomics study took advantage of the sequencing of the Culex quinquefasciatus genome" says Professor Muskavitch, "to bring together data from experiments profiling responses of mosquito genes to pathogen infections, directed by Professor Lyric Bartholomay, with the results of comparative immunogenomics analyses led by Dr Robert Waterhouse". This study revealed many differences among these three mosquito species, and also that Culex, the most geographically widespread, "has an expanded immune gene repertoire, which may enhance its ability to adapt to diverse habitats with different pathogen challenges", explains Dr Waterhouse.

"These important studies" says Professor Zdobnov, "highlight how genome sequencing can greatly facilitate detailed experimental investigations to uncover the complex biology of these major disease-vector mosquitoes". Professor Bartholomay, from Iowa State University, adds that "by comparing numerous combinations of mosquito species infected with different pathogen types, our results indicate that pathogens that successfully develop in, and are transmitted by, disease-vector mosquitoes, have evolved to avoid mosquito immune responses". Improving our understanding of these vector-pathogen relationships significantly advances the long-term objectives of developing strategies to reinforce the mosquitoes' defences, making them immune to infections and breaking the chain of pathogen transmission.


'/>"/>

Contact: Irene Perovsek
irene.perovsek@isb-sib.ch
41-216-924-050
Swiss Institute of Bioinoformatics
Source:Eurekalert

Page: 1 2

Related biology technology :

1. deCODE Discovers Major Genetic Risk Factor for the Most Common Form of Glaucoma
2. All-New Sermo Brings Major Enhancements to Nations Largest Online Physician Community
3. deCODE Discovers Genetic Risk Factor Linking Susceptibility to Four Major Vascular Diseases
4. Iowa Gains Momentum as Major Provider of Biorenewables
5. Orexigen(R) Therapeutics Announces That Contrave(R) Reduced Depression Scores and Body Weight in Overweight and Obese Patients With Major Depression
6. University of Minnesota researchers clear major hurdle in road to high-efficiency solar cells
7. Lexicon to Present at Two Major Healthcare Investor Conferences
8. Sensient Technologies Corporation Announces Major Investment in Natural Colors
9. Encorium Group, Inc. Announces New Business Contract Wins of $6.8 Million, Including Two Pivotal Phase III Studies for a Major Asian Technology Company
10. Epeius Biotechnologies Reports Major Clinical Advances: Noteworthy Clinical Case Studies in Cancer Gene Therapy
11. Graphene films clear major fabrication hurdle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Oct. 20, 2014 PureTech , a ... big healthcare problems, announced today the closing of ... participation from Invesco Perpetual, a $120 Billion group ... drive PureTech,s existing pipeline forward and to advance ... the scientific creativity to really go for the ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 The Latin ... the market in Latin America with analysis and forecast ... in 2013, and is expected to reach $2,366.8 million ... to 2018. , Browse through the TOC of the ... idea of the in-depth analysis provided. It also provides ...
(Date:10/19/2014)... The Asian Automatic patient billing report ... and forecast of revenue. The Automatic patient billing market ... million by 2018, at a developing CAGR of 7.2% ... of the Asian Automatic patient billing market, to get ... provides a glimpse of the segmentation of this market ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 The ... Defense, & Homeland Security), Technology, Payload, Type & ... and segments the global unmanned ground vehicle market ... and forecasting of market sizes. The report also ... and opportunities impacting it along with the adoption ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5
... ... peptide synthesis reagents and catalogue peptides. New pricing positions Mimotopes as the supplier of ... ... a subsidiary of Commonwealth Biotechnologies Inc. (NASDAQ Capital Market: CBTE), is pleased to announce ...
... CALGARY, Oct. 23 /PRNewswire-FirstCall/ - Dr. Brad Thompson, President ... ONCY ), will present a corporate overview of ... 2009 on Wednesday, October 28, 2009 at 3:00 p.m. ... Hotel in San Francisco on October 28 and 29, ...
... N.M. Sandia National Laboratories, National Institute for Nano-Engineering ... Research Corp., has won a "Deal of Distinction" award ... The award a glass sculpture will be ... innovative educational approach called NINE to facilitate student education ...
Cached Biology Technology:Mimotopes Launches Online Peptide Superstore 2Mimotopes Launches Online Peptide Superstore 3Media Advisory - Oncolytics Biotech Inc. to Present at BIO Investor Forum 2009 2Sandia, SRC win LES award for NINE program outreach 2
(Date:10/18/2014)... suspected genetic conditions, a certain type of exome sequencing ... than traditional molecular diagnostic methods, according to a study ... released to coincide with the American Society of Human ... protein­coding region of the genome (the complete set of ... organism), has been rapidly applied in research settings and ...
(Date:10/16/2014)... Cancer constantly wages war on the human body. ... a stalemate. In pancreatic cancer, this stalemate—known as ... becoming aggressively malignant, a phenomena that is poorly ... in the laboratory of Salvatore Torquato, a Professor ... the conditions surrounding tumor dormancy and the switch ...
(Date:10/16/2014)... Syncytial Virus causes severe respiratory tract infections and ... year. Scientists at VIB and Ghent University have ... counteract this common virus infection. , Xavier ... that paves the way for the development of ... virus that causes suffering in numerous small children ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Modeling tumor dormancy 2New perspectives for development of an RSV vaccine 2
... When people have similar injuries, why do some end up ... The first longitudinal brain imaging study to track participants with ... all in their heads - quite literally. A ... chronic pain develops the more two sections of the brain ...
... in tissue engineering and regenerative medicine could one day make ... muscle tissue that could be cut into steaks without ever ... out of many kinds of tissue, but one of the ... the cells within large structures from suffocating; organs have complicated ...
... analyzed, for the first time, how a potted plant,s roots are ... to be presented at the Society for Experimental Biology meeting on ... size makes plants grow over 40% larger. From their ... extend their roots to the pot,s walls. It is likely that ...
Cached Biology News:Why chronic pain is all in your head 2Penn researchers improve living tissues with 3-D printed vascular networks made from sugar 2Penn researchers improve living tissues with 3-D printed vascular networks made from sugar 3Penn researchers improve living tissues with 3-D printed vascular networks made from sugar 4Penn researchers improve living tissues with 3-D printed vascular networks made from sugar 5
...
D.R. Harper and C. Grose (1994) • Includes: virus structure & replication, fundamental virology, immunology and pathogenesis, vaccines and antiviral drugs, novel diagnostic techniques, cloning a...
IHC Polymer Detection Kit (Rabbit DAB)150 slides...
...
Biology Products: