Navigation Links
Major disease-vector mosquito reveals the secrets of its immune system
Date:10/1/2010

1st October 2010 - The Culex quinquefasciatus mosquito poses a significant threat to human health as a blood-sucking transmitter of elephantiasis-causing worms and encephalitis-inducing viruses. An international team of scientists, including researchers from the University of Geneva and the SIB Swiss Institute of Bioinformatics sequenced its genome and studied its responses to pathogen infections. Two articles published in today's issue of Science, describe results from comparing the Culex mosquito with the malaria mosquito, Anopheles gambiae, and the dengue mosquito, Aedes aegypti, which offer new insights into the elimination of insect-transmitted diseases that seriously impact on global public health.

Mosquitoes are the most important disease-vectors. Species of Culex, Aedes, and Anopheles mosquitoes are responsible for the transmission of many human pathogens including parasites that cause malaria, viruses that trigger dengue and yellow fever, and West Nile encephalitis, as well as worms that cause lymphatic filariasis (also called elephantiasis). The capacity of different mosquito species to transmit these and other pathogens varies greatly, and much of this variation can be attributed to the mosquito immune system's ability to recognise and eliminate the pathogen. Applying their expertise in comparative evolutionary genomic analyses and insect immunity, Professor Evgeny Zdobnov and Dr Robert Waterhouse, from the University of Geneva Medical School and the SIB Swiss Institute of Bioinformatics, joined forces with scientists from around the world to examine the Culex genome and its encoded genes.

Sequencing of the Culex genome, directed by Peter Atkinson and Peter Arensburger from the University of California Riverside, allowed researchers to perform a thorough comparison among the three disease-vector mosquito species. Focusing on the mosquito immune system, researchers led
'/>"/>

Contact: Irene Perovsek
irene.perovsek@isb-sib.ch
41-216-924-050
Swiss Institute of Bioinoformatics
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology technology :

1. deCODE Discovers Major Genetic Risk Factor for the Most Common Form of Glaucoma
2. All-New Sermo Brings Major Enhancements to Nations Largest Online Physician Community
3. deCODE Discovers Genetic Risk Factor Linking Susceptibility to Four Major Vascular Diseases
4. Iowa Gains Momentum as Major Provider of Biorenewables
5. Orexigen(R) Therapeutics Announces That Contrave(R) Reduced Depression Scores and Body Weight in Overweight and Obese Patients With Major Depression
6. University of Minnesota researchers clear major hurdle in road to high-efficiency solar cells
7. Lexicon to Present at Two Major Healthcare Investor Conferences
8. Sensient Technologies Corporation Announces Major Investment in Natural Colors
9. Encorium Group, Inc. Announces New Business Contract Wins of $6.8 Million, Including Two Pivotal Phase III Studies for a Major Asian Technology Company
10. Epeius Biotechnologies Reports Major Clinical Advances: Noteworthy Clinical Case Studies in Cancer Gene Therapy
11. Graphene films clear major fabrication hurdle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... Clinverse, Inc. , a ... trials, today announced it will be exhibiting and ... in Boston, June 24-26, 2013. Clinverse’s eClinical ... fully configurable, cloud-based clinical financial lifecycle system. , ... Clinverse’s eClinical Commerce Network, automates site contract set-up ...
(Date:6/19/2013)... Calif. , June 19, 2013 ... plant, stool and other challenging microbial nucleic acid ... Protein Extraction Kit, for extraction of pure protein ... protein world coincides with the 20 th ... growing innovation capabilities. (Photo: http://photos.prnewswire.com/prnh/20130619/LA32633 ...
(Date:6/19/2013)... CLEVELAND , June 19, 2013   NineSigma ... announced that a year following its launch, NineSights.com ... and a focal point for the worldwide community of ... to climate and environmental sustainability experts, NineSights stands out ... broad range of scientific and technical disciplines, all vetted ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 Today DuPont ... young people to become leaders in the greatest challenge ... billion people in 2050. Borel spoke at the ... Conference in Atlanta, about urgent need for students to ... are local, science-based, sustainable and reached in collaboration with ...
Breaking Biology Technology:Clinverse, Inc. Exhibiting and Showcasing Its Technology at DIA 2013 2MO BIO Laboratories, Inc. launches the first kit for protein extraction from soil 2NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 2NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 3DuPont Leader Calls for New Generation of Food Visionaries to Fight Hunger 2
... Purpose , ... this series describes an LC/MS/MS method for the simultaneous determination ... FK-506), Sirolimus (SIR, aka Rapamycin) and Everolimus (EVE, aka RAD-001) ... robust hardware configuration and shows to be fast and simple, ...
... , ... As the study of protein biomarkers increases in ... protein pathway information and discovery-based proteomics experiments. Even larger numbers of ... gene expression studies or other genomic information. , ...
... Purpose , ... non-nucleoside reverse transcriptase inhibitor (NNRTI) antiretroviral drugs is of significant ... metabolism variability. To be of practical use, it is essential ... fast and easy to perform, with minimal sample preparation, and ...
Cached Biology Technology:A new LC/MS/MS Research Method for Rapid Quantitation of Five Immunosuppressant Drugs, including Mycophenolic Acid (MPA) 2A new LC/MS/MS Research Method for Rapid Quantitation of Five Immunosuppressant Drugs, including Mycophenolic Acid (MPA) 3A new LC/MS/MS Research Method for Rapid Quantitation of Five Immunosuppressant Drugs, including Mycophenolic Acid (MPA) 4A new LC/MS/MS Research Method for Rapid Quantitation of Five Immunosuppressant Drugs, including Mycophenolic Acid (MPA) 5Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 2Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 3Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 4Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma 5A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 2A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 3A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors) 4
(Date:6/19/2013)... Elsevier, a world-leading provider of scientific, technical and medical ... launch of a new open access journal, GeoResJ ... , Elsevier,s earth and planetary science journals portfolio has ... to provide a forum for rapid publication of top ... will be co-edited by six Executive Editors, each covering ...
(Date:6/18/2013)... the University of Calgary,s Faculty of Medicine have discovered ... from harmful bacteria. Platelets, a component of blood typically ... specific bacteria, and upon detection, seal it off from ... published in Nature Immunology this week, provide ... , "The science community has known that platelets do ...
(Date:6/18/2013)... environmental engineer has been awarded a $394,300 grant ... water quality and flow in the new facilities ... Kruzic, UT Arlington associate professor of civil engineering, ... add monochloramine to the water in an effort ... stations and pipelines. Adding monochloramine is widely practiced ...
Breaking Biology News(10 mins):Immunity mechanism discovered 2UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2
... orchids have been found to rely on a wide ... of the soil instead of producing their own organic ... the open access journal BMC Biology , also ... and Mlanie Roy, from the Centre d,Ecologie Fonctionnelle et ...
... Carnegie Mellon University have developed an analytical technique to ... disease syndromes such as diabetes, asthma and cancer, which ... Rather than searching one at a time for genetic ... as in most conventional approaches, the Carnegie Mellon scientists ...
... Water striders, the familiar semi-aquatic bugs gliding across the ... allows them to walk on water. This was not ... evolution of a unique arrangement of the legs, with the ... of Ecology and Evolutionary Biology have discovered the gene behind ...
Cached Biology News:Carnegie Mellon develops innovative method to detect genetic causes of complex diseases 2
... for quick and reproducible immunoprecipitation (IP) by using ... more reproducible than regular IPs, which are problematic ... without disrupting the agarose bed. The binding of ... reversible, and elution of the immune complex can ...
... Kit (V2), 2 x 11K will ... of many thousands of yeast genes ... biological processes. Each microarray contains sequences ... from the S288C strain of Saccharomyces ...
... require screening through a huge volume ... data from normal biologic diversity. The ... available to help better manage the ... inherent to biomarker discovery. The CiphergenExpress ...
... Immunoprecipitation kit allows a rapid and ... active FLAG-tagged protein. The immunoprecipitation is ... is a highly specific monoclonal antibody ... use of affinity resin allows an ...
Biology Products: