Navigation Links
Living cells behave like fluid-filled sponges
Date:1/7/2013

Animal cells behave like fluid-filled sponges in response to being mechanically deformed according to new research published today in Nature Materials.

Scientists from the London Centre for Nanotechnology (LCN) at UCL have shown that animal cells behave according to the theory of 'poroelasticity' when mechanically stimulated in a way similar to that experienced in organs within the body. The results indicate that the rate of cell deformation in response to mechanical stress is limited by how quickly water can redistribute within the cell interior.

Poroelasticity was originally formulated to describe the behaviour of water-saturated soils and has important applications in the fields of rock engineering and petro-physics. It is commonly used in the petroleum industry. Poroelastic models describe cells as being analogous to fluid-filled sponges. Indeed, cells are constituted of a sponge-like porous elastic matrix (comprising the cytoskeleton, organelles, and macromolecules) bathed in an interstitial fluid (the cytosol).

In this analogy, the rate at which the fluid-filled sponge can be deformed is limited by how fast internal water can redistribute within the sponge in response to deformation. This rate is dictated by three parameters: the stiffness of the sponge matrix, the size of the pores within the sponge matrix, and the viscosity of the interstitial fluid.

To study cellular responses, LCN scientists used cell-sized levers to apply rapid well-controlled deformations on the cell surface and monitored the temporal response of cells to these deformations. Close examination of the experimental results revealed that the rate of cellular deformation was limited by how rapidly water could redistribute within the cell interior. Experimental measurements indicated that this sponge-like behaviour of cells likely occurs during normal function of organs such as the lungs and the cardiovascular system.

Emad Moeendarbar
'/>"/>

Contact: Clare Ryan
clare.ryan@ucl.ac.uk
44-077-475-65056
University College London
Source:Eurekalert

Page: 1 2

Related biology technology :

1. 3-D movies in your living room -- without the glasses
2. Novo Nordisk To Award $80,000 To Local Programs That Help People Living With Diabetes In Detroit As Part Of Educational Initiative
3. JCVI Researchers, as Part of NIH Human Microbiome Project Consortium, Publish Papers Detailing the Variety and Abundance of Microbes Living on and in the Human Body
4. Harvards Wyss Institute creates living human gut-on-a-chip
5. Systems Alliance Launches Redesigned Website for The Living Legacy Foundation of Maryland
6. CellerateRX® Added to List of Preferred Products for Golden Living Healthcare Network
7. Mesenchymal Stem Cells Mobilize Body’s Own Healing Cells According to New Research Published in STEM CELLS Translational Medicine
8. Autoimmune disease retraining white blood cells
9. Breast cancer cells growing in 3D-matrix revert to normal
10. The birth of new cardiac cells
11. On the hunt for rare cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Institute for Molecular Medicine Finland (FIMM), University of ... novel "man and machine" decision support system for ... described in PLOS One scientific journal ... computer vision algorithms similar to those used in ... the diagnostically most relevant areas. Tablet computers can ...
(Date:8/21/2014)... Aug. 21, 2014 Telomere Biosciences, LLC ... Nutraceutical "TELO-20 for Dogs" with Telomerase Activation ... in the world for dogs. Telomeres are the ... in the body. A wealth of ground-breaking research ... Telomere Science and Aging, including Nobel laureates, has ...
(Date:8/21/2014)... , Aug. 21, 2014  China Cord Blood Corporation (NYSE: ... plan to release financial results for the first quarter ... after market close in the US.  ... a.m. ET on Friday, August 29, 2014 to discuss ... the Company,s recent developments, followed by a question and ...
(Date:8/21/2014)... 2014 SoundConnect , a ... as one of the nation’s Fastest Growing Private ... the 2nd consecutive year. Inc. magazine today ranked ... 500|5000, an exclusive ranking of the nation's fastest-growing ... look at the most important segment of the ...
Breaking Biology Technology:A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3
... BEDFORD, Mass., Sept. 2 VisEn Medical Inc., a leader ... today the commercial launch of its new Annexin-Vivo 750 imaging ... . The new Annexin-Vivo 750 agent is based on ... It is expected to significantly expand research areas and enhance drug development ...
... , , SAN DIEGO, Sept. 2 ... OPTR ) lead developmental product candidates will be ... and Chemotherapy (ICAAC) to be held at The Moscone Center in San ... http://www.newscom.com/cgi-bin/prnh/20090413/LA97352LOGO ) , , , ...
... , SILVER SPRING, Md., Sept. 1 United Therapeutics ... of Directors has approved and declared a stock split. The ... dividend, in which one share of United Therapeutics common stock will ... (or held in treasury) at the close of business on the ...
Cached Biology Technology:VisEn Launches New Annexin-Vivo 750 Fluorescence Molecular Imaging Agent 2VisEn Launches New Annexin-Vivo 750 Fluorescence Molecular Imaging Agent 3Optimer Pharmaceuticals Announces Presentations of Additional Phase 3 Fidaxomicin and Prulifloxacin Data at Upcoming ICAAC Annual Meeting 2Optimer Pharmaceuticals Announces Presentations of Additional Phase 3 Fidaxomicin and Prulifloxacin Data at Upcoming ICAAC Annual Meeting 3United Therapeutics Corporation Announces Stock Split To Be Effected as a Stock Dividend 2
(Date:8/22/2014)... . , Thanks ... in a way so as to align themselves symmetrically, ... University researchers are planning on looking into how PCFs ... being published today in the scientific journal Nature ... Everyone knows that at least from having boiled ...
(Date:8/22/2014)... tea polyphenols are strong antioxidants and can ... spinal cord neurons against oxidative stress? Jianbo ... Hospital of Liaoning Medical University, China discovered ... stress and inhibit neuronal apoptosis, indicating green ... spinal cord neurons under oxidative stress. The ...
(Date:8/22/2014)... 2015, American consumers will finally be able to purchase ... touted as zero-emissions vehicles, most of the cars will ... fuel that contributes to global warming. , Now scientists ... that uses an ordinary AAA battery to produce hydrogen ... current through two electrodes that split liquid water into ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 3
... Saturday 02 April 2011: Promising new viral hepatitis data ... entry inhibitors --a new mechanism of action for drugs ... new hepatitis B and hepatitis D treatments for many ... replication (e.g. nucleotide/side analogues), and can lead to the ...
... greenhouse industry is big business in the United ... agricultural sales. Most of the ornamental plants grown ... greenhouse operations. These operations are classified as "intensive ... expensive resources (labor, water, and fertilizers) to produce ...
... on England,s unused agricultural land could produce enough biomass ... industry or the environment, according to research led by ... The study, funded by the UK Energy Research Centre ... which looks at the potential of planting short rotation ...
Cached Biology News:Entry inhibitors show promise as drugs with new MOA for treatment of HBV and HDV infection 2Green industry knowledge center introduced 2Green industry knowledge center introduced 3Short rotation energy crops could help meet UK's renewable energy targets 2
... The Fujifilm Life Science FLA-7000 excels at ... CBB-stained gel documentation. It features four easy-to-access ... and a filter for Imaging Plates) for ... a customizable choice of four kinds of ...
... has been optimized for the analysis of ... software to quickly and accurately locate and ... an ELISA plate or each section of ... been customized to incorporate standard ELISA analysis ...
For microscopy...
... General description: Humidity wells in the ... maintain chamber humidity and probe hydration around ... seal eliminates the risk of waterbath contamination. ... constant temperature waterbaths or hybridisation ovens. Linkage: ...
Biology Products: