Navigation Links
Living cells behave like fluid-filled sponges
Date:1/7/2013

Animal cells behave like fluid-filled sponges in response to being mechanically deformed according to new research published today in Nature Materials.

Scientists from the London Centre for Nanotechnology (LCN) at UCL have shown that animal cells behave according to the theory of 'poroelasticity' when mechanically stimulated in a way similar to that experienced in organs within the body. The results indicate that the rate of cell deformation in response to mechanical stress is limited by how quickly water can redistribute within the cell interior.

Poroelasticity was originally formulated to describe the behaviour of water-saturated soils and has important applications in the fields of rock engineering and petro-physics. It is commonly used in the petroleum industry. Poroelastic models describe cells as being analogous to fluid-filled sponges. Indeed, cells are constituted of a sponge-like porous elastic matrix (comprising the cytoskeleton, organelles, and macromolecules) bathed in an interstitial fluid (the cytosol).

In this analogy, the rate at which the fluid-filled sponge can be deformed is limited by how fast internal water can redistribute within the sponge in response to deformation. This rate is dictated by three parameters: the stiffness of the sponge matrix, the size of the pores within the sponge matrix, and the viscosity of the interstitial fluid.

To study cellular responses, LCN scientists used cell-sized levers to apply rapid well-controlled deformations on the cell surface and monitored the temporal response of cells to these deformations. Close examination of the experimental results revealed that the rate of cellular deformation was limited by how rapidly water could redistribute within the cell interior. Experimental measurements indicated that this sponge-like behaviour of cells likely occurs during normal function of organs such as the lungs and the cardiovascular system.

Emad Moeendarbar
'/>"/>

Contact: Clare Ryan
clare.ryan@ucl.ac.uk
44-077-475-65056
University College London
Source:Eurekalert

Page: 1 2

Related biology technology :

1. 3-D movies in your living room -- without the glasses
2. Novo Nordisk To Award $80,000 To Local Programs That Help People Living With Diabetes In Detroit As Part Of Educational Initiative
3. JCVI Researchers, as Part of NIH Human Microbiome Project Consortium, Publish Papers Detailing the Variety and Abundance of Microbes Living on and in the Human Body
4. Harvards Wyss Institute creates living human gut-on-a-chip
5. Systems Alliance Launches Redesigned Website for The Living Legacy Foundation of Maryland
6. CellerateRX® Added to List of Preferred Products for Golden Living Healthcare Network
7. Mesenchymal Stem Cells Mobilize Body’s Own Healing Cells According to New Research Published in STEM CELLS Translational Medicine
8. Autoimmune disease retraining white blood cells
9. Breast cancer cells growing in 3D-matrix revert to normal
10. The birth of new cardiac cells
11. On the hunt for rare cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/26/2015)... ... 2015 , ... PRC Clinical, a Clinical Trial Management Expert CRO, ... in southern California. The Clinical Trial Management Expert CRO seeks to introduce more California-based ... , Stem Cell Meeting on the Mesa on October ...
(Date:8/25/2015)... 2015   WuXi PharmaTech (Cayman) Inc. (NYSE: ... platform company serving the pharmaceutical, biotechnology, and medical device ... Kong Exchange Stock Code: 0950), a research-based biopharmaceutical company ... 20 years of operations in China ... an agreement whereby WuXi,s Laboratory Testing Division (LTD) will ...
(Date:8/25/2015)... ... August 25, 2015 , ... Vets ... in Knapp, Wis. The company has added a AS16 Sharples centrifuge to harvest ... collection during bacterial or fungal fermentation process development. , The new centrifuge ...
(Date:8/25/2015)... ... 25, 2015 , ... One of the world’s foremost authorities on supply chain ... has been on a mission for the past two weeks. She’s been scrambling to ... from the two massive explosions that occurred on August 12 at the Ruihai International ...
Breaking Biology Technology:PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 2PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 3WuXi PharmaTech to Be Exclusive Supplier of Laboratory Testing Services to Lee's Pharm 2WuXi PharmaTech to Be Exclusive Supplier of Laboratory Testing Services to Lee's Pharm 3New centrifuge and fermentor expand product development capacity at Vets Plus 2Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 2Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 3Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 4
... , PHILADELPHIA, Dec. 3 Shire plc (LSE: SHP, Nasdaq: ... a voluntary recall of five lots and voluntary market withdrawal ... ® . Shire is taking this action because some Daytrana ... meet their release liner removal specification, and as a result, ...
... , , COLUMBIA, Md., Dec. 2 ... it intends to release the results of its fourth quarter and ... Eastern Time (ET). Following the release, at 4:45 p.m. ET ... investors. All interested parties may listen to the call live ...
... , NEW YORK, Dec. 2 Nearly 600 ... to explore novel development approaches and innovative funding strategies at ... FasterCures, the Washington-based center of the Milken Institute, ... needed to turn a scientific discovery into an accessible therapy. ...
Cached Biology Technology:Non-safety-related voluntary recall of a limited portion of Daytrana(R) (methylphenidate transdermal system) patches announced 2Non-safety-related voluntary recall of a limited portion of Daytrana(R) (methylphenidate transdermal system) patches announced 3Non-safety-related voluntary recall of a limited portion of Daytrana(R) (methylphenidate transdermal system) patches announced 4Non-safety-related voluntary recall of a limited portion of Daytrana(R) (methylphenidate transdermal system) patches announced 5Martek to Announce Fourth Quarter and Fiscal Year 2009 Results 2Medical Research Leaders Explore Novel Strategies to Expedite the Search for Cures 2
(Date:8/12/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced that four of its fingerprint ID products, ... been named FIDO Certified™ by the Fast IDentity ... Synaptics, Natural ID™ fingerprint solutions are fully compliant ... standard and are interoperable among other products and ...
(Date:8/10/2015)... 10, 2015 The latest 364 page ... analysis of the global border security market . ... $16.4bn in 2015. Now: Border security is hard ... of the business critical issue you need to know about ... ,s objective analysis of how this will impact your company ...
(Date:8/6/2015)... Calif. , Aug. 6, 2015 ... developer of human interface solutions, today announced collaboration ... technologies on Windows 10. Microsoft leveraged Synaptics, deep ... the operating system. Through stringent ... are fully certified with Microsoft,s Precision TouchPad (PTP) ...
Breaking Biology News(10 mins):Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9Synaptics Chosen for Human Interface Co-Development on Windows 10 2
... University of Pittsburgh,s Department of Biological Sciences to encourage ... been rewarded with two prestigious grants totaling $2 million ... as the renewed appointment of department chair and Eberly ... Professors nationwide and the only one in Pennsylvania. ...
... in plots to blow up the London subway, among other ... planned to pack some of his bombs with toxic gas. ... his accomplices before they could carry out their attacks. ... failed, at some point someone might succeed. The right ...
... from a shrub called the burning bush, known for ... in biofuels and low-calorie food oils, according to Michigan ... applied to seeds of the species Euonymus alatus -- ... the gene responsible for its manufacture of a novel, ...
Cached Biology News:Pitt's education of aspiring undergrad, high school biologists rewarded with $2 million 2'Scrubbing' chemical-contaminated buildings clean with lasers 2'Scrubbing' chemical-contaminated buildings clean with lasers 3Research promises healthier vegetable oil -- and tractor fuel to harvest it 2
... Highly nutritious peptone, used ... production of bacterial toxins, ... of bacteria with high ... Haemophilus, Neisseria, Pasteurella, Salmonella ...
... Human Raji cells were cultured in RPMI ... at the log phase of growth. In ... forms, cells were fixed in acetone-methanol. The ... adhesive coated slide, with each wells surface specifically ...
... in Minimum Essential Medium (Eagle) with 2 mM ... growth. In order to keep the antigens ... acetone-methanol. The cells are arrayed on a ... wells surface specifically treated to enhance cellular attachment ...
CELLine System cultivation flask (for secreted products)...
Biology Products: