Navigation Links
Kiadis Pharma Reports ATIR(TM) Clinical Data, Further Supporting its Potential in Mismatched Bone Marrow Transplantations
Date:4/8/2009

AMSTERDAM, April 8 /PRNewswire/ -- Biopharmaceutical company Kiadis Pharma reported preliminary clinical data on ATIR(TM) showing its potential in mismatched bone marrow transplantations. Data was presented by the company's principal investigator Dr. Denis Claude Roy during the prestigious Presidential Symposium at the Annual European Bone Marrow Transplantation meeting (EBMT) in Goteborg, Sweden, on Monday, March 30, 2009. Only the 6 highest ranked presentations, representing the most promising new developments in the transplantation field, were selected for this Symposium.

ATIR(TM), a donor lymphocyte cell based preparation depleted of allo-reactive T-cells, is under development to prevent acute Graft versus Host Disease (GvHD) and allow for early immune reconstitution following a bone marrow transplantation with a fully mismatched (haplo-identical) donor.

Dr. Roy's presentation of clinical results from 19 end stage blood cancer patients with high risk leukemia and/or lymphoma using ATIR(TM) was very well received. These patients, each of whom did not have a matched donor available, were treated in a phase I/II dose escalating study with ATIR(TM) in a mismatched transplantation setting. No immune suppressants were used, which is in contrast to conventional transplant procedures. Nevertheless, no cases of severe grade III/IV acute GvHD occurred after ATIR(TM) infusion. Furthermore, the clinical data showed a reduction in the frequency of infectious episodes in the cohorts treated with the higher doses of ATIR(TM), as compared to the low dose cohorts. To date, patients in the higher dose cohorts show high survival rates (75%) with no transplant related mortality (TRM).

These results show that the selective depletion of allo-reactive T-cells in the ATIR(TM) cell based product by the proprietary photo-sensitizing agent TH9402 is highly effective and can result in fast and adequate immune reco
'/>"/>

SOURCE Kiadis Pharma
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Kiadis Pharma Appoints Dr. Maarten Egeler, MD PhD as Chief Medical Officer
2. Kiadis Pharma Announces Continued Collaboration With Professor Velardi on its Lead Product ATIR(TM)
3. EMEA Grants Kiadis Pharma Lead Product ATIR(TM) Orphan Drug Designation
4. Kiadis Pharma Receives Orphan Drug Designation for Rhitol(TM) From the FDA
5. Kiadis Pharma Reports Successful End of Phase II Meeting With FDA for Reviroc
6. Pharmatech Oncology Selected to Present at Company Showcase at BIOZONA
7. Biostar Pharmaceuticals, Inc. Reports Record Revenues and Earnings for 2008
8. Intrasphere Technologies Releases Version 1.5 of Its PharmaCM Clinical Trial Registration Solution Powered by Microsoft
9. New Pharmaxis Board Appointment
10. Pharmaxis Investor Conference Call
11. Gemin X Pharmaceuticals Selects and Deploys Clinical Force CTMS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... FORT LAUDERDALE, Fla. , Sept. 17, 2014 ... signed an agreement to form a Special Purpose Vehicle in ... based Jatropha centric agro energy company. The SPV shall ... U.S. registered entity with AFAI as majority shareholder. The SPV ... Africa , particularly Ethiopia . ...
(Date:9/17/2014)... California , 17 de septiembre de ... ("la compañía"), principal proveedor mundial de soluciones ... las ciencias de la vida, anunció hoy ... de logística global con sede en Rótterdam, ... base de clientes Europa en rápido crecimiento. ...
(Date:9/17/2014)... NASA’s MESSENGER has just celebrated its 10 ... to have one of its latch valves, V27200-818, operating ... scientific investigation of the planet Mercury. It is only ... has provided a vast amount of information and images ... valves utilize solenoids that also include permanent magnets to ...
(Date:9/16/2014)... NEW YORK , Sept. 16, 2014 This ... by the following Product Segments: Software, Hardware, and Biocontent. The ... Canada , Japan , ... Latin America , and Rest of World. Annual estimates ... Also, a seven-year historic analysis is provided for these markets. ...
Breaking Biology Technology:AFAI Signs Joint Venture Agreement With Jatro Greentech Inc. 2AFAI Signs Joint Venture Agreement With Jatro Greentech Inc. 3Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 2Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 3Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 4Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 5Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23
... ST. JOSEPH, Mich., July 16 GeneGo, Inc., ... biology and pathway,analysis, today announced that the University ... certified GeneGo Center of Excellence (COE). Miller,School of ... and advanced support. COE will provide a pathway ...
... Cell Therapeutics, Inc.,(CTI) (Nasdaq and MTA: CTIC) ... Patients and Providers Act of 2008, which,includes an ... such as Zevalin(R) (Ibritumomab Tiuxetan), overriding,President Bush,s veto., ... U.S. House of Representatives on,June 24, 2008 and ...
... the ... Treatment of Stuttering, ROANOKE, Va., ... non-profit research and,clinical center ( http://www.stuttering.org ) specializing ... stuttering,therapy with advanced behavioral, electronic and computer technologies that,significantly improve ...
Cached Biology Technology:University of Miami Miller School of Medicine Becomes a GeneGo Center of Excellence 218-Month Extension of Reimbursement Rates for Radioimmunotherapies Becomes Law After Congressional Override of Presidential Veto 218-Month Extension of Reimbursement Rates for Radioimmunotherapies Becomes Law After Congressional Override of Presidential Veto 3Video: New, Advanced Therapy Program Helps People Who Stutter Acquire Fluent Speech 2Video: New, Advanced Therapy Program Helps People Who Stutter Acquire Fluent Speech 3
(Date:9/16/2014)... the Columbia Center for Children,s Environmental Health at the ... demonstrate an association between childhood asthma and prenatal exposure ... household products. Results appear online in the journal ... mothers exposed during pregnancy to higher levels of the ... a 72 percent and 78 percent increase in risk ...
(Date:9/16/2014)... brakes" that time the generation of important cells in ... translate sound waves into electrical signals that are carried ... the arrangement of the cells is disordered, hearing is ... be published in The Journal of Neuroscience ... act as brakes to prevent hair cell generation until ...
(Date:9/16/2014)... species has its own bacterial identity. That,s the conclusion ... institutions who studied the genetic fingerprints of bacteria on ... , "This study demonstrates for the first time that ... ecological strategies possess very different microbial communities on their ... postdoctoral researcher in the UO,s Institute of Ecology and ...
Breaking Biology News(10 mins):Phthalates heighten risk for childhood asthma 2Phthalates heighten risk for childhood asthma 3Hey1 and Hey2 ensure inner ear 'hair cells' are made at the right time, in the right place 2Microbiome research shows each tree species has a unique bacterial identity 2
... an infectious question about eating at restaurants: How clean ... Pascall found that even when they washed dishes in ... to levels accepted in the Food and Drug Administration's ... and milk—can be safe havens for bacteria when dried ...
... with an overt reaction to toxins that cause oxidative ... health threats. , At the 233rd American Chemical Society ... Tech and the Edward Via Virginia College of Osteopathic ... biosensor prototype and correlations to brain tissue damage. ...
... level have on the activation of the female ... a researcher at the Cognitive Neuroscience Center (CNRS/Université ... from the National Institute of Mental Health (Bethesda, ... the first time, the neural networks involved in ...
Cached Biology News:Manual dishwashing study digs up dirt on dish cleanliness 2Manual dishwashing study digs up dirt on dish cleanliness 3Bacterial response to oxidation studied as toxin barometer 2Bacterial response to oxidation studied as toxin barometer 3The influence of the menstrual cycle on the female brain 2The influence of the menstrual cycle on the female brain 3The influence of the menstrual cycle on the female brain 4
... Software has been optimized for the analysis ... the software to quickly and accurately locate ... of an ELISA plate or each section ... has been customized to incorporate standard ELISA ...
For microscopy...
... description: Humidity wells in the base hold ... humidity and probe hydration around the edges ... the risk of waterbath contamination. This chamber ... waterbaths or hybridisation ovens. Linkage: This CLS ...
... R offers maximum application versatility for ... and cooling. Its active heating/cooling function ... temperature control ranges. Five different thermoblocks, ... test tubes, are available for: 0.5 ...
Biology Products: