Navigation Links
Jennerex Reports Positive Phase 1 Results for JX-594 Administered Intravenously
Date:5/20/2010

SAN FRANCISCO and WASHINGTON, May 20 /PRNewswire/ -- Jennerex, Inc., a clinical-stage cancer biotherapeutics company, today reported positive results from its Phase 1 dose escalation study evaluating the intravenous (IV) administration of JX-594 to patients with metastatic cancer.  The data presented today demonstrated clear dose-related delivery to solid tumors, cancer-targeted replication and gene expression, and anti-cancer effects of JX-594 delivered IV.  Choi (necrotic) responses were more commonly observed in patients treated at higher doses.  In addition, intravenous infusion of JX-594 was safe and well-tolerated.  These data were presented today at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting in Washington DC.

"These data represent a significant milestone for the field of oncology and viral therapy as this is the first time that a viral or genetic product has demonstrated reproducible, biopsy-proven delivery to multiple solid tumor types following intravenous administration," said David H. Kirn, M.D., president and chief executive officer of Jennerex.  "We look forward to extending our experience with IV JX-594 in our planned Phase 3 trial in patients with advanced liver cancer.  This pivotal trial will utilize both IV and targeted intratumoral injections of JX-594 to maximize potential patient benefit.  We expect to initiate this study in Q4 of 2010."

"JX-594 represents a promising potential treatment option for patients with multiple types of cancer.  As the first intravenous biological immunotherapy to demonstrate safety and tumor-specific delivery, JX-594 may add significantly to the armamentarium for many solid tumors," stated '/>"/>

SOURCE Jennerex, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Jennerex Appoints Bob Ingram Special Advisor and Hires Marty Glick as EVP, Corporate Strategy
2. Jennerex Completes $8.3 Million Series B Financing and Appoints Dr. Cal Stiller as Director
3. Jennerex Appoints Samantha Miller as Vice President of Corporate Development
4. Nature Reviews Publishes Article About Jennerexs Multi-Mechanistic Cancer Therapeutic
5. Jennerex Closes $5 Million First Tranche of Series C Financing
6. Jennerex Completes Over-Subscribed Series C Financing for Aggregate Gross Proceeds of Over $5.5 Million
7. Jennerex Adds Industry Veteran Paul Cleveland to Board of Directors
8. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
9. QMed, Inc. Reports July Medicare SNP Enrollments
10. Phlo Affiliate Reports Expanded Coverage to Oregon Border
11. Healthcare Technologies Reports Loss for 2007 Second Quarter & Six Months Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... 2014  Asterias Biotherapeutics, Inc. (NYSE MKT: AST), ... of regenerative medicine, today announced that the Company,s ... complete cervical spinal cord injury (SCI), has been ... Projects to Watch" by Elsevier Business Intelligence. ... industry honor, which represents independent validation of the ...
(Date:11/17/2014)... The new METTLER TOLEDO White Paper " Traceability ... becoming the first calibration laboratory in the world ... the microgram range. National Metrology Institutes (NMI's), private ... in nanotechnology applications will benefit from understanding the ... weights in the range of 0.05 mg to ...
(Date:11/16/2014)... (PRWEB) November 16, 2014 James Hill ... With Filtered Fume Hoods, 3 Years Later” scheduled for ... fall of 2011, Butler University surprised many in the ... in their organic chemistry and general chemistry teaching laboratories ... due to building age and substantial growth within the ...
(Date:11/15/2014)... FL (PRWEB) November 14, 2014 ... scientifically validated physical activity and sleep measurement platform ... improved subject experience along with multiple new channels ... and secondary accelerometer. Equipped with Bluetooth Smart technology, ... capture and mobile data uploads to ActiGraph’s cloud-based ...
Breaking Biology Technology:Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 2Asterias Biotherapeutics Named as a "Top Advanced Therapies Projects to Watch" and Will Present at the Therapeutic Area Partnerships Conference 3New White Paper on Microgram Weights Describes How to Achieve Traceable Measurement Down to 0.05 Milligrams 2Don't miss the I2SL High-Tech Talks Webinar Series Presenting: Butler University's Renovation With Filtered Fume Hoods, 3 Years Later 2Don't miss the I2SL High-Tech Talks Webinar Series Presenting: Butler University's Renovation With Filtered Fume Hoods, 3 Years Later 3ActiGraph Launches GT9X Link Activity Monitor 2
... , ... combines many of Haydon Kerk’s patented motion technologies into a single integrated system. ... simplifying product integration for the OEM. , ... Waterbury, CT (PRWEB) June 21, 2010 -- Haydon Kerk Motion ...
... ... facility as part of the Utah Science Technology and Research (USTAR) project on the U of U ... Salt Lake City, Utah (Vocus) June 19, ... firms in the U.S., is assisting in the construction of a new USTAR facility at the University ...
... The Reproductive Health Drugs Advisory Committee met today to discuss the ... Hypoactive Sexual Desire Disorder (HSDD) in pre-menopausal women.  The advisory committee was ... (FDA).  The FDA will consider the committee,s advice as part of its ... , , ...
Cached Biology Technology:Haydon Kerk Motion Solutions Introduces the RGS04 Dual Carriage Linear Rail and Programmable Actuator Assembly 2Bigge Helps Build New USTAR Complex at the University of Utah 2
(Date:11/5/2014)... professor of biology in the UTSA College of ... nation selected to receive a two-year $300,00 National ... Research (EAGER). The funding supports President Obama,s BRAIN ... create new technology that will demystify complex brain ... in neuroscience are broken into the interactions of ...
(Date:11/4/2014)... Medicine announced today that it is a Grand ... Bill & Melinda Gates Foundation. Laura Goetzl, ... Sciences; and Vice Chair of Research and Academic ... pursue an innovative global health and development research ... Neurodevelopment.", Grand Challenges Explorations (GCE) funds individuals worldwide ...
(Date:11/4/2014)...   Neurotechnology , a provider of high-precision ... version of its fingerprint matching algorithm has achieved ... evaluation organized by NIST. The MINEX test measures ... 378 fingerprint standard template format. MINEX compliance is ... the United States and ...
Breaking Biology News(10 mins):UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3Temple University School of Medicine receives Grand Challenges Explorations grant 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3
... living sensor that can spot contamination. They have also ... even in previously untreatable cold areas, microbiologists heard today ... Microbiology,s Autumn meeting being held this week at Trinity ... in the sub-arctic. It contains over 230,000 tonnes of ...
... a new method to fabricate borosilicate glass ... nanoparticles are more stable when subjected to ... currently used nanoparticles made of polymers or ... range of potential nanoparticle applications in biomedical, ...
... MD The Biophysical Society is pleased to announce ... recipients will receive their awards at the Society,s 53rd ... Boston Convention and Exhibitions Center in Massachusetts. The awardees ... California, San Francisco, will receive the Anatrace Membrane Protein ...
Cached Biology News:Living sensor can warn of arsenic pollution 2Biophysical Society names 2009 award recipients 2
... min) assay can detect H2O2 or peroxidase ... H2O2 oxidizes ADHP in a 1:1 stoichiometry ... at 530-571 nm, emission at 590-600 nm). ... a one-step, homogeneous, no wash assay system. ...
...
Rabbit polyclonal to Staphylococcus Enterotoxin A (HRP) ( Abpromise for all tested applications)....
... better net results - with a modular ... data management! The ChemStation Plus NDS family ... data acquisition and data management, giving you ... meets your labs needs now and that ...
Biology Products: