Navigation Links
Japan Bioinformatics Announces Study on Leading Mapping Tools for DNA Mutation Discovery
Date:12/4/2012

Tokyo, Japan (PRWEB) December 03, 2012

Japan Bioinformatics, today announced results of a study on the impact three popular mapping tools have on the results of SNP discovery experiments and the analysis of sequence data.

Mutation discovery, especially discovery of single nucleotide polymorphisms (SNPs) is an extremely popular analysis of sequence data in many types of research, including cancer. The data from Next Generation Sequencing (NGS) devices provides a very cost-effective and convenient source of information. Additionally, the proliferation of NGS-focused data analysis tools makes this type of research easily accessible to individual researchers.

Japan Bioinformatics recently published a study, which utilizes Simbiot®, a cloud-based next generation sequencing data analysis tool, to explore the impact three popular mapping tools have on the results of SNP discovery experiments.

Bowtie, Bowtie2 and BWA mapping tools were tested using data from a human cancer panel, a human exome and Caenhorhabditis elegans whole genome. In all three cases, the results were consistent:

  • Bowtie detected the smallest number of SNPs and almost no insertions or deletions (INDELs)
  • Bowtie2 and BWA were able to detect a similar number of mutations
  • There were significant discrepancies between the SNPs detected using Bowtie2 and those detected using BWA
  • The results of INDEL analysis in the human exome data set show that 67% of the filtered, high quality INDELs were common between mutations detected using Bowtie2 and those detected using BWA genome aligners.

For the complete results of the analysis, download the white paper,

About Japan Bioinformatics
Japan Bioinf
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
2. First Baby With Artificial Heart in Japan
3. Snoasis Medical Initiates Distribution in Japan Through Hausten Healthcare
4. Life Technologies Signs Licensing Agreement with iPS Academia Japan for Global Patent Portfolio Rights to Induced Pluripotent Stem Cell Technology
5. Immunomic Therapeutics Receives IND Authorization for Phase I Study of JRC-LAMP-Vax Vaccine to Treat Japanese Red Cedar (Sugi) Allergy
6. Regulus Receives Allowance from Japan and U.S. Patent Offices for HCV Intellectual Property, Expanding Leading Worldwide Patent Estate
7. Generex Announces Patent Award for its Core Vaccine Technologies in Japan
8. CoreLab Partners Opens Office in Tokyo, Japan
9. Global Bioinformatics Industry
10. The Scientist Proudly Announces the Top 10 Innovations of 2012
11. Bayer CropScience Announces LibertyLink LinkUp Offer Increased for 2013 Season
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... , Aug. 27, 2015 HUYA Bioscience International ... of the Japan Society of HTLV-1, held this week ... The purpose of the Society is to promote research ... development of medical technology and research related to these ... "HUYA is proud to support this prestigious ...
(Date:8/27/2015)... ... 27, 2015 , ... Proove Biosciences, a commercial and ... of genetics and hypertension at the International Academy of Cardiology Annual ... Canada. The event, which boasts an extensive overview of the latest research developments ...
(Date:8/26/2015)... -- The Diabetes Research Institute (DRI), a Center of ... of Medicine, announced today that the first patient ... first time a novel transplant technique for insulin-producing ... I/II study builds upon decades of progress in ... step toward the development of the DRI BioHub, ...
(Date:8/26/2015)... , August 26, 2015 After litigating ... Europlasma NV relating to P2i United States ... their dispute in the United States ... the part of either party. As a result of the ... of California dismissed the case without ...
Breaking Biology Technology:HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 2Proove Biosciences Presents Ground-Breaking Data on Genetics and Heart Disease at 20th World Congress on Heart Disease 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 2Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 4P2i Settles United States Litigation 2
... Fusion2006 CEO-CIO Symposium this month that companies should ... their core competency and push it outside of the organization. ... work in house raises a lot of questions, so WTN ... experience in IT and outsourcing. , ,This is part one ...
... been chosen to lead an effort to report medical outcomes ... be based on the level of technology investment. , ,WCHQ ... a practical method of collecting performance data from physician practices ... both physicians and consumers. While the vision for this information ...
... Madison, Wis. Berbee Information Networks ... Systems' U.S. IP communications partner of the year ... and customer satisfaction related to Berbee's sales and ... president of Berbee's Cisco practice, said it's the ...
Cached Biology Technology:IT outsourcing according to Tom Koulopoulos, part 1 2IT outsourcing according to Tom Koulopoulos, part 1 3Healthcare quality initiative shuns high-tech for now 2
(Date:8/12/2015)... Aug. 12, 2015  New research unveiled at ... Android phones to steal users, fingerprints. Information released ... of fingerprint scanners on mobile devices, making the ... secure biometrics on mobile devices, HYPR Corp. recently ... convenient authentication systems with strong cryptographic security. More ...
(Date:8/6/2015)... Calif. , Aug. 6, 2015  Today, ... will visit Crossmatch ™ to learn firsthand ... and protect data. Crossmatch is a world leader ... technologies and expertise are helping federal agencies and ... and security.   "The vast majority ...
(Date:8/5/2015)... The biosensors market is proving highly attractive ... newer sectors, and development of devices resulting in higher ... seen the entry of multiple participants each year with ... (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ) Recent ... Global Biosensors Market ( http://www.frost.com/nee9 ), finds that ...
Breaking Biology News(10 mins):HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 3Rep. Honda to Visit Crossmatch in Redwood City 2Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4
... some regions and increasing global demand for high quality ... globally. This was the main conclusion of a special ... The special report follows a strategic workshop on ... of international trade" held on 25th - 26th November ...
... to evaluate the effect of Best Available Techniques (BAT) at ... and soil. The initiative is co-funded by the Interreg Atlantic ... laboratory is equipped with diverse equipment to take and keep ... used to monitor in situ gas emissions. The mobile laboratory ...
... fish, and have a devastating effect on fish reproduction, ... some of the first evidence that global warming affects ... study from the University of Leicester revealed that global ... parasite and host - with potentially serious implications for ...
Cached Biology News:Experts call on governments, industries and the water and trade research communities 2Neiker-Tecnalia sets up a mobile laboratory to reduce the environmental impact of farms 2Global warming changes balance between parasite and host in fish -- new study 2
... the computing power of your ValveBank system! ... a PC computer running Windows 98, 2000, XP ... programs to disk, print out program listings, then ... one simple step., EasyCode is used for programming ...
Porcine Aortic Smooth Muscle Cells (PAOSMC) (>500,000 cells)...
Bovine Renal Artery Smooth Muscle Cells (BRASMC) (>500,000 cells)...
Porcine Aortic Endothelial Cells (PAOEC) (>500,000 cells)...
Biology Products: