Navigation Links
Japan Bioinformatics Announces Study on Leading Mapping Tools for DNA Mutation Discovery
Date:12/4/2012

Tokyo, Japan (PRWEB) December 03, 2012

Japan Bioinformatics, today announced results of a study on the impact three popular mapping tools have on the results of SNP discovery experiments and the analysis of sequence data.

Mutation discovery, especially discovery of single nucleotide polymorphisms (SNPs) is an extremely popular analysis of sequence data in many types of research, including cancer. The data from Next Generation Sequencing (NGS) devices provides a very cost-effective and convenient source of information. Additionally, the proliferation of NGS-focused data analysis tools makes this type of research easily accessible to individual researchers.

Japan Bioinformatics recently published a study, which utilizes Simbiot®, a cloud-based next generation sequencing data analysis tool, to explore the impact three popular mapping tools have on the results of SNP discovery experiments.

Bowtie, Bowtie2 and BWA mapping tools were tested using data from a human cancer panel, a human exome and Caenhorhabditis elegans whole genome. In all three cases, the results were consistent:

  • Bowtie detected the smallest number of SNPs and almost no insertions or deletions (INDELs)
  • Bowtie2 and BWA were able to detect a similar number of mutations
  • There were significant discrepancies between the SNPs detected using Bowtie2 and those detected using BWA
  • The results of INDEL analysis in the human exome data set show that 67% of the filtered, high quality INDELs were common between mutations detected using Bowtie2 and those detected using BWA genome aligners.

For the complete results of the analysis, download the white paper,

About Japan Bioinformatics
Japan Bioinf
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
2. First Baby With Artificial Heart in Japan
3. Snoasis Medical Initiates Distribution in Japan Through Hausten Healthcare
4. Life Technologies Signs Licensing Agreement with iPS Academia Japan for Global Patent Portfolio Rights to Induced Pluripotent Stem Cell Technology
5. Immunomic Therapeutics Receives IND Authorization for Phase I Study of JRC-LAMP-Vax Vaccine to Treat Japanese Red Cedar (Sugi) Allergy
6. Regulus Receives Allowance from Japan and U.S. Patent Offices for HCV Intellectual Property, Expanding Leading Worldwide Patent Estate
7. Generex Announces Patent Award for its Core Vaccine Technologies in Japan
8. CoreLab Partners Opens Office in Tokyo, Japan
9. Global Bioinformatics Industry
10. The Scientist Proudly Announces the Top 10 Innovations of 2012
11. Bayer CropScience Announces LibertyLink LinkUp Offer Increased for 2013 Season
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2015)... , May 21, 2015  The EveryLife ... Hatch (R-UT) and Amy Klobuchar ... Now Accelerating Cures & Treatments, or OPEN ACT. ... disease patient advocacy organizations, this bipartisan legislation promises ... affordable medicines to rare disease patients by incentivizing ...
(Date:5/21/2015)... 21, 2015 Patent Offering, The patent’s ... diagnostic or therapeutic imaging within a body lumen (open ... endoscope having a low cost, single-use disposable illumination and ... was October 18, 2013 and the patent approval was ... the physician to customize the lighting and magnification of ...
(Date:5/21/2015)... , May 20, 2015 Research and Markets ... addition of the "2015 Global Survey on ... offering. The primary goal of this ... cytometry instruments and reagents. Key information the survey ... selection of flow cytometers, predominantly used applications for ...
(Date:5/21/2015)... Prussia, PA (PRWEB) May 21, 2015 ... O’Neill has joined the firm as senior statistician and ... 30 years of experience in the management and analysis ... biologics, pharmaceutical and chemical industries. , “We’re delighted to ... longstanding capabilities in data analytics,” said Dr. Philippe Cini, ...
Breaking Biology Technology:Advocates Cheer Senate Leaders for Introducing Bipartisan Bill to Increase Number of Rare Disease Treatments 2IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 2IpAuctions™ Presents The Worlds Smallest Disposable Illuminated Endoscope For Auction 3Global Survey on Flow Cytometry Adoption Trends 2015 2Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2
... Acquisition Expected to Add New Drug Products to Aida Pharmaceuticals, ... ... MONICA, Calif., March 27 Aida,Pharmaceuticals, Inc. (OTC Bulletin Board: ... to acquire a controlling interest,in one of the leading microbiology ...
... Pharmasset, Inc.,(Nasdaq: VRUS ), a pharmaceutical company ... treat viral infections, is,pleased to announce the appointment ... the,Board of Directors and the Nominating and Corporate ... the Board of Directors of Sapphire,Therapeutics, a Director ...
... Led by OrbiMed Advisors, World,s Largest Healthcare ... ... a,bio-pharmaceutical company developing Anticalins(R), a novel class of,targeted human protein therapeutics, ... by new investor OrbiMed Advisors LLC, a major global fund dedicated,to ...
Cached Biology Technology:Aida Pharmaceuticals, Inc. Acquires High-Level Research Institute in the People's Republic of China 2Aida Pharmaceuticals, Inc. Acquires High-Level Research Institute in the People's Republic of China 3Pharmasset Appoints Herbert J. Conrad as a Director 2Pharmasset Appoints Herbert J. Conrad as a Director 3Pieris Raises EUR 25 M (US$ 38 M) in Series B Financing Round 2Pieris Raises EUR 25 M (US$ 38 M) in Series B Financing Round 3Pieris Raises EUR 25 M (US$ 38 M) in Series B Financing Round 4
(Date:5/20/2015)... , May 20, 2015 NXT-ID, Inc. (NASDAQ: ... its wholly owned subsidiary, 3D-ID LLC, a company engaged ... Battelle for the biometrics technology portion of the recently ... from the Department of the Army. 3D-ID ... developed for government, law enforcement and security agencies. ...
(Date:5/18/2015)... May 18, 2015 Fingerprint Cards (FPC) ... FPC1025, FPC1145, FPC1155 and FPC1035 from one if its module ... and including Q3 2015 and the sensors will be used ... order values for 2015 hereby amount to 740 MSEK to ... of 140 MSEK and a number of smaller orders not ...
(Date:5/11/2015)... , May 11, 2015  Through a well-rounded UAS ... had a strong showing at AUVSI,s Unmanned 2015 ... representatives of Ohio,s UAS industry met ... abroad from all points along the UAS ecosystem. ... Coalition,s (DDC) Vice President for Aerospace Rich Knoll . ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2
... Palo Alto, CA Researchers at the Carnegie Institution,s ... link in the so-called signaling pathway for plant steroid ... molecules that start at the cell surface and cascade ... the first such pathway in plants for which all ...
... for many a person this is the greatest of pleasures. ... we drink beer as it is among the most energy-intensive ... (TUM) are working hard to improve the energy balance of ... combination that would allow energy savings of up to 20% ...
... periodontitis, a form of gum disease, is an independent ... This suggests the need for increased efforts to prevent ... the risk of this form of cancer. "Prevent ... maintain good oral hygiene," said Mine Tezal, D.D.S., Ph.D., ...
Cached Biology News:Plants on steroids: Key missing link discovered 2Environmentally 'green' beer: Munich brewing engineers research energy savings 2Environmentally 'green' beer: Munich brewing engineers research energy savings 3Prevent periodontitis to reduce the risk of head and neck cancer 2
Mouse IL-31 RA Biotinylated Affinity Purified PAb...
Sf21 cells derived from Spodoptera frugiperda ovarian cells are recommended for high-level production of recombinant proteins. Higher expression levels of some proteins are seen due to the larger ce...
... universal lysis buffer, PCR mix, DNA polymerase ... l volume PCR reactions. This system can ... positive rod and coccus bacteria, such as ... Aureus, Streptococcus Agalactiae, and etc. With the ...
...
Biology Products: