Navigation Links
Japan Bioinformatics Announces Study on Leading Mapping Tools for DNA Mutation Discovery
Date:12/4/2012

Tokyo, Japan (PRWEB) December 03, 2012

Japan Bioinformatics, today announced results of a study on the impact three popular mapping tools have on the results of SNP discovery experiments and the analysis of sequence data.

Mutation discovery, especially discovery of single nucleotide polymorphisms (SNPs) is an extremely popular analysis of sequence data in many types of research, including cancer. The data from Next Generation Sequencing (NGS) devices provides a very cost-effective and convenient source of information. Additionally, the proliferation of NGS-focused data analysis tools makes this type of research easily accessible to individual researchers.

Japan Bioinformatics recently published a study, which utilizes Simbiot®, a cloud-based next generation sequencing data analysis tool, to explore the impact three popular mapping tools have on the results of SNP discovery experiments.

Bowtie, Bowtie2 and BWA mapping tools were tested using data from a human cancer panel, a human exome and Caenhorhabditis elegans whole genome. In all three cases, the results were consistent:

  • Bowtie detected the smallest number of SNPs and almost no insertions or deletions (INDELs)
  • Bowtie2 and BWA were able to detect a similar number of mutations
  • There were significant discrepancies between the SNPs detected using Bowtie2 and those detected using BWA
  • The results of INDEL analysis in the human exome data set show that 67% of the filtered, high quality INDELs were common between mutations detected using Bowtie2 and those detected using BWA genome aligners.

For the complete results of the analysis, download the white paper,

About Japan Bioinformatics
Japan Bioinformatics KK is a Tokyo-based biotechnology company specializing in software development, as well as bioinformatics and information technology services to the life science community, including biotechnology, academia, research, pharmaceutical and bio-devices organizations.

Our main product is Simbiot ®, a system for management and analysis of biological data. The application is available in single-user and private server configuration that easily integrates into client’s environment, including laboratory information management systems (LIMS), as well as custom and proprietary data formats, analytics and annotations. The system combines reliable data management, distribution, collaboration and analysis tools that support commercial and proprietary data formats with specific focus on next generation sequencing (NGS) data.

In addition to software products, Japan Bioinformatics offers, we also offer data analysis, bioinformatics and software development services. Learn more at http://www.japanbioinformatics.com.

# # #

Read the full story at http://www.prweb.com/releases/2012/12/prweb10148356.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
2. First Baby With Artificial Heart in Japan
3. Snoasis Medical Initiates Distribution in Japan Through Hausten Healthcare
4. Life Technologies Signs Licensing Agreement with iPS Academia Japan for Global Patent Portfolio Rights to Induced Pluripotent Stem Cell Technology
5. Immunomic Therapeutics Receives IND Authorization for Phase I Study of JRC-LAMP-Vax Vaccine to Treat Japanese Red Cedar (Sugi) Allergy
6. Regulus Receives Allowance from Japan and U.S. Patent Offices for HCV Intellectual Property, Expanding Leading Worldwide Patent Estate
7. Generex Announces Patent Award for its Core Vaccine Technologies in Japan
8. CoreLab Partners Opens Office in Tokyo, Japan
9. Global Bioinformatics Industry
10. The Scientist Proudly Announces the Top 10 Innovations of 2012
11. Bayer CropScience Announces LibertyLink LinkUp Offer Increased for 2013 Season
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... ... October 10, 2017 , ... ... program has won a US2020 STEM Mentoring Award. Representatives of the FirstHand program ... in Volunteer Experience from US2020. , US2020’s mission is to change the trajectory ...
(Date:10/10/2017)... CALIFORNIA (PRWEB) , ... October 10, 2017 , ... ... technological innovation and business process optimization firm for the life sciences and healthcare ... BoxWorks conference in San Francisco. , The presentation, “Automating GxP Validation for ...
(Date:10/9/2017)... ... , ... At its national board meeting in North Carolina, ARCS® Foundation ... of Physics and Astronomy, has been selected for membership in ARCS Alumni Hall ... 2015 Breakthrough Prize in Fundamental physics for the discovery of the accelerating expansion of ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... Hi-C metagenome deconvolution product, featuring the first commercially available Hi-C kit. Researchers ... perform Hi-C metagenome deconvolution using their own facilities, supplementing the company’s full-service ...
Breaking Biology Technology:
(Date:4/17/2017)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... 2016 Annual Report on Form 10-K on Thursday April 13, 2017 ... ... Investor Relations section of the Company,s website at http://www.nxt-id.com  under ... http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ... appointment of independent Directors Mr. Robin D. Richards ... Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive ... their guidance and benefiting from their considerable expertise as we ...
Breaking Biology News(10 mins):