Navigation Links
JCI early table of contents for Aug. 15, 2013
Date:8/16/2013

Biomarkers predict time to ovarian cancer recurrence

Ovarian cancer often remains undetected until it is at an advanced stage. Despite positive responses to initial treatment, many patients are at risk of tumor recurrence. A multitude of genetic markers have been implicated in ovarian cancer prognosis. However, the genetic testing required is not practical or affordable in a clinical setting. In this issue of the Journal of Clinical Investigation, Roel Verchaak and colleagues at the MD Anderson Cancer Center identify protein biomarkers that are predictive for time of ovarian cancer recurrence and develop a PRotein-driven index of OVARian cancer (PROVAR). Using PROVAR, the authors were able to discriminate between patients with high and low risk of cancer recurrence, as well as short-term and long-term survival prognosis. In combination with genetic diagnosis, analysis of protein biomarkers may be useful in predicting outcome and determining a treatment plan for ovarian cancer patients.

TITLE: Predicting Time to Ovarian Carcinoma Recurrence Using Protein Markers

AUTHOR CONTACT: Roel G.W. Verhaak
MD Anderson Cancer Center, Houston, TX, USA
Phone: 7135632293; E-mail: RVerhaak@mdanderson.org

View this article at: http://www.jci.org/articles/view/68509?key=d03afe0843e018bcf8a0


A molecule involved in development of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is characterized by poor airflow due to the breakdown of lung tissue, mucus accumulation and airway dysfunction. Development of COPD is most commonly associated with smoking tobacco, however, it also occurs after acute respiratory infections such as influenza. It is unclear how prior lung disease leads to COPD. In th
'/>"/>

Contact: Corinne Williams
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Netsmart Clients to Receive Nearly $2 Million in Meaningful Use EHR Incentive Payments
2. Access BridgeGap Ventures to Focus on Early-Stage Therapeutic Opportunities
3. VisionGate Uses $2.6 Million NIH Grant to Achieve Full Automation of Cell-CT™ 3D Imaging System for Early Diagnosis of Cancer
4. Sequenom Announces 2011 Operational Highlights and Early 2012 Outlook
5. CSL Behring Study Confirms Early Treatment with Berinert® Provides Faster Resolution of Acute Hereditary Angioedema Symptoms
6. Corporate Venturing and Early-Stage Financing in the Spotlight at BioTrinity
7. Butamax Early Adopters Group surpasses capacity targets with addition of Big River; Membership represents 11 production facilities and nearly 900 million gallons of ethanol capacity
8. Researchers peek at the early evolution of sex chromosomes
9. Discuss Early Results of the DIAN Trial at CBIs 6th Annual Alzheimers Drug Development Summit
10. Early career distinction: Prestigious award recognizes physicists work in electron dynamics
11. JCI early table of contents for Sept. 4, 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... March 3, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX) ... scientific journal, Expert Opinion on Biological Therapy , ... Zhenggang Zhang , at the Henry Ford Hospital ... Thymosin beta 4 (TB4) has the capacity to promote ... or more post-injury, leading to neurological recovery in each ...
(Date:3/3/2015)... CARLOS, Calif. , March 3, 2015  Rosa ... expertise in drug-disease modeling and simulation research, today announced ... the 2015 American Society for Clinical Pharmacology and Therapeutics ... March 3-7 2015.   Logo - ... and Rosa will present a poster describing a quantitative ...
(Date:3/3/2015)... 3, 2015 Kindred Biosciences, Inc. (NASDAQ: ... the lives of pets, announced today that it will release ... 12, 2015 after the market close. The Company will host ... Interested parties may access the call by ... internationally, and using conference ID 98449349.  The ...
(Date:3/3/2015)... Genedata, a leading provider of advanced ... research, today announced that Pfizer Inc. has licensed ... at Pfizer biopharma research and development sites in ... global deployment and roll out project at Pfizer’s ... (CTI), and Pharmaceutical Sciences groups. , “Pfizer ...
Breaking Biology Technology:Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 2Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 3Rosa & Co. Announces Two Poster Presentations at the American Society for Clinical Pharmacology and Therapeutics 2015 Annual Meeting 2Rosa & Co. Announces Two Poster Presentations at the American Society for Clinical Pharmacology and Therapeutics 2015 Annual Meeting 3Genedata Biologics Licensed by Pfizer Inc. 2Genedata Biologics Licensed by Pfizer Inc. 3
... 2 The Foundation for,Biomedical Research (FBR) congratulates ... DeBakey the highest civilian honor it can bestow, ... to cardiovascular medicine,have improved the health of millions ... extraordinary talents as a surgeon, inventor, educator and,medical ...
... Roche Files CTA for Third Genmab Antibody,Summary: Genmab,s Partner Roche has ... ... Genmab Antibody, COPENHAGEN, October 2 Genmab ... Clinical Trial,Application (CTA) with the British Medicines and Healthcare products,Regulatory Agency ...
... N.J., Oct. 2 Synvista Therapeutics,Inc. (Amex: SYI ... Chief Executive Officer will present at the BIO InvestorForum,2007 ... BIO InvestorForum will,be held on October 9 - 11, ... Dr. Berkowitz will discuss the company,s planned and/or ...
Cached Biology Technology:Foundation for Biomedical Research Board Chairman Awarded Congressional Gold Medal 2Genmab A/S - Company Announcement 2Synvista Therapeutics to Present at the BIO InvestorForum 2007 2Synvista Therapeutics to Present at the BIO InvestorForum 2007 3
(Date:2/5/2015)... IRVINE, Calif. , Jan. 27, 2015 ... trusted provider of globally deployed, innovative test ... today announced the delivery of its ... Martin Space Systems Company (LMSSC). GENASYS is ... the demands of mission-critical applications that require ...
(Date:2/5/2015)... Calif. , Feb. 3, 2015 ... technology, demand from industries such as consumer electronics, ... market for surface mount technology (SMT) screen printers. ... to automatic control will push the adoption curve ... will remain steady as glue dispensers are indispensable ...
(Date:1/22/2015)... Technology Showcase, Hall E -   EyeLock Inc. , ... it will showcase its EyeLock ID technology integrated in a ... Energy,s Oak Ridge National Laboratory (ORNL) at the ... identity authentication technology is being used to validate the driver ...
Breaking Biology News(10 mins):Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3
... Va.Coinciding with the observance of Nuclear Medicine Week (October ... (October), SNM released today a new fact sheet highlighting ... improving the ways in which breast cancer is diagnosed ... effective, safe and painless imaging tool for diagnosing and ...
... a study in mice has found that inactivating a ... increase energy expenditure and help lower diet-induced obesity. These ... might lead to some new roads in weight-loss ... to continually "burn fat" in order to maintain body ...
... of spring: a swarm of bees on the move. But how ... of the community know the way remains a mystery. Curious to ... homes, Tom Seeley, a neurobiologist from Cornell University, and engineers Kevin ... to find out how swarms are guided to their new home ...
Cached Biology News:SNM releases new fact sheet on breast cancer and molecular imaging 2Making metabolism more inefficient can reduce obesity 2Bee swarms follow high-speed 'streaker' bees to find a new nest 2
... designed for easy transformation of the budding ... successful transformation simply by mixing a plasmid ... yeast cells. No complicated steps, such as ... kit is particularly well suited for high-throughput ...
... system, offers fast and reliable batch processing ... Ultra Evolution , SAFIRE monochromator reader , ... , LS Series of Laser Scanners , ... range of detection and separation systems, Connect ...
... STag Purification Kits enable rapid analytical to ... proteins produced from appropriate vectors. Sufficient reagents ... 1 mg target protein under native or ... S-protein Agarose, which specifically retains STag fusion ...
High affinity antibody reacting with S-100 ab heterodimer. Could be used for Western blotting application and immunoassay....
Biology Products: