Navigation Links
Increased fertility rate for IVF patients achieved by new equipment design
Date:2/29/2012

A novel system for processing embryos during IVF treatment has been shown to significantly improve the chances of pregnancy by more than a quarter.

Pioneered by a Newcastle team of fertility experts at the University and within the NHS, the innovative design of interlinked incubators provides a totally enclosed and controlled environment within which every step of the IVF process can be performed.

Research published today in the journal PLoS ONE reveals that the introduction of the new system into the Newcastle Fertility Centre at Life, part of the Newcastle Hospitals NHS Foundation Trust, resulted in a 27% increase in pregnancy rate compared with conventional equipment used in IVF treatment labs.

Traditionally, in IVF procedures embryos are cultured in incubators, which provide a controlled environment. However, it is necessary to check embryo development under the microscope.

This generally involves removing them from the controlled environment of the incubators, which may be harmful. The system developed by the Newcastle team overcomes this problem by enabling all procedures to be conducted within an enclosed and controlled environment.

Initially the new system was tested extensively to make sure that it maintained stable environmental conditions (for air quality and temperature). Subsequent studies on embryos donated to research showed a significant increase in the proportion of embryos developing normally over a period of 6-7 days.

After introduction into the laboratories at Newcastle Fertility Centre at Life, the team were able to compare the treatment outcomes over a period of three years. The study, found that 45% achieved a clinical pregnancy compared to 32% and 35% in each of the preceding two years. This represents a minimum increase of 27% in the clinical pregnancy rate; a clinical pregnancy means that a heart beat was seen on the scan at 7 weeks gestation.

The study, which took account of variability between patients, included women aged 37 or less, undergoing their first cycle of IVF or ICSI, and who had more than ten ovarian follicles (the structures which contain a mature egg).

This is the first and only system of its kind to be installed in the UK, however, based on the innovative design from the Newcastle team, similar systems have already been exported to IVF clinics in the Netherlands, Canada and Thailand.

This positive benefit to IVF patients came from investment into cutting edge research in embryonic stem cell research and was funded by the Medical Research Council and One North East.

Newcastle University's Professor Mary Herbert who led the research team at Newcastle Fertility Centre at Life, part of the Newcastle Hospitals NHS Foundation Trust and based at the Centre for Life, said: "Our aim was to keep eggs and embryos in conditions similar to those they would experience naturally - inside a woman's body. This led our team to design and develop a system in which it is possible to perform all of the technical procedures while maintaining stable conditions throughout the IVF process."

Alison Murdoch, Professor of Reproductive Medicine who leads the clinical service at Newcastle Fertility Centre at Life said: "Growing good embryos is the key to IVF success and everyone, even those who have a very small prospect of success, deserve to have the best possible chance. Since installing this new technology over 850 babies have now been born."


'/>"/>

Contact: Karen Bidewell
karen.bidewell@ncl.ac.uk
44-191-222-6972
Newcastle University
Source:Eurekalert

Related biology technology :

1. Downsizing and the Need for Increased Selling Effectiveness Fuel Delta Points Growth
2. Amgen’s Third Quarter 2011 Revenue and Adjusted Earnings Per Share (EPS) Each Increased 3 Percent to $3.9 Billion and $1.40
3. Dendreon Announces Increased Capacity and Significant Reimbursement Decisions Supporting Broad Availability of PROVENGE
4. Dune Medicals MarginProbe™ Demonstrates Increased Positive Margin Identification Leading to Reduction in Patients Indicated for Re-excision in Landmark Lumpectomy Surgery Trial
5. US Dominance in Scientific Research Significantly Challenged by Increased Competition from Europe and Asia, According to Thomson Reuters Study
6. Proposition 19 Decision Prompts Cannabis Science to Anticipate Increased Demand for its Pharmaceutical Products for Critical Ailments and Begin the Formal Application Process for FDA Clinical Trials Immediately
7. Shire plc: Continued Excellent Performance in Q3, Full Year Earnings Expectations Increased, New Value in Pipeline Emerging
8. Sigma-Aldrich (Nasdaq: SIAL) Reports Q3 2010 Diluted EPS of $0.76. Diluted EPS Increased by 9% and 19% on a Reported and Adjusted Basis, Respectively. Q3 Sales Performance Remains Strong; Full Year 2010 Diluted Adjusted EPS Outlook Raised to $3.20 -
9. Reportlinker Adds Downstream Processing in Biopharmaceuticals - Increased Demand for Biologics Drives Improvement in Cost -effective Purification Technologies
10. Study Finds BYETTA(R) Use Was Not Associated With Increased Rate of Acute Pancreatitis Compared to Other Antidiabetic Drugs: Final Results Presented at ADA 2010
11. Meta-Analysis of SYMLIN(R) Clinical Data Showed No Increased Risk of Cardiovascular Adverse Events Associated With SYMLIN Treatment in Patients With Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2017)... ... 2017 , ... The recent vote by the American Medication Association to align ... to patients and hopefully sheds new light on the way health insurers, governments and ... and founding partner of Texas Fertility Center . , “This designation is ...
(Date:6/27/2017)... ... 27, 2017 , ... According to a recent report from ... not have negative short- or long-term effects on benthic communities. , The ... located at the Puget Sound Naval Shipyard & Intermediate Maintenance Facility in Bremerton, ...
(Date:6/26/2017)... ... June 26, 2017 , ... NDA Partners Chairman Carl ... Product Development R&D at Allergan and CMC expert with more than twenty-five years ... biopharma companies, has joined the firm as an Expert Consultant. , ...
(Date:6/26/2017)... ... June 26, 2017 , ... Two new members were elected to ... June 9, 2017: Jeremy Nowak, President, J Nowak Strategy and Michele Masucci, Ph.D., Vice ... election of Glen N. Gaulton and Kenneth L. Kring, and re-election of David P. ...
Breaking Biology Technology:
(Date:3/30/2017)... 30, 2017  On April 6-7, 2017, Sequencing.com will ... hackathon at Microsoft,s headquarters in ... focus on developing health and wellness apps that provide ... the Genome is the first hackathon for personal ... largest companies in the genomics, tech and health industries ...
(Date:3/30/2017)... 2017 Trends, opportunities and forecast in this ... technology (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, ... end use industry (government and law enforcement, commercial and ... and others), and by region ( North America ... Asia Pacific , and the Rest of the ...
(Date:3/28/2017)... 2017 The report "Video Surveillance ... Servers, Storage Devices), Software (Video Analytics, VMS), and Service ... Forecast to 2022", published by MarketsandMarkets, the market was ... projected to reach USD 75.64 Billion by 2022, at ... base year considered for the study is 2016 and ...
Breaking Biology News(10 mins):