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IFRS Information - First Half of 2007
Date:9/13/2007

revenue growth reported in US dollars includes the impact of translating the sales made in a local currency into US dollars. The table below shows the effect of foreign exchange translations on the revenue growth of the key affected products as well as the underlying performance of three key products in their local currency:

6 months to

June 30, 6 months to

2007 sales June 30,

6 months to growth in 2007 sales Impact of

June 30, local growth in translation

2007 sales currency US dollars to US

$'M % % dollars

___________ ___________ ___________ __________

XAGRID sales in Euros 20.0 +17 +27 +10

REPLAGAL sales in Euros 32.1 +5 +13 +8

XAGRID sales in Pounds

sterling 11.6 +2 +11 +9

CALCICHEW sales in Pounds

sterling 23.0 +5 +16 +11

REMINYL and REMINYL XL

sales in Pounds sterling 13.3 +44 +58 +14

REPLAGAL sales in Pounds

sterling 6.0 +2 +9 +7

___________ ___________ ___________ __________

Royalties

Royalty revenue increased by 2% to $123.5 million for the six months to June 30, 2007 (2006: $121.4 million). The following table provides an analysis of Shire's royalty income:

6 months to 6 months to

June 30, June 30,

2007 2006 change


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SOURCE Shire plc
Copyright©2007 PR Newswire.
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