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IFRS Information - First Half of 2007




PENTASA 84.0 62.6 +34 +6

LIALDA 5.0 - N/A N/A


FOSRENOL 47.3 13.9 N/A +12

DYNEPO 1.9 - N/A N/A

CALCICHEW 25.6 22.1 +16 N/A

CARBATROL 33.4 30.3 +10 -5


XAGRID 31.6 26.2 +21 N/A

Other product

sales 52.6 57.8 -9

__________ __________ __________

832.0 667.9 +25

__________ __________ __________

Human Genetic


REPLAGAL 64.4 54.1 +19 N/A


__________ __________ __________

133.7 54.1 N/A

__________ __________ __________

Total product sales

965.7 722.0 +34

__________ __________ __________

The following discussion includes references to prescription and market share data for Shire's key products. The source of this data is IMS Health, June 2007. IMS Health is a leading global provider of business intelligence for the pharmaceutical and healthcare industries.


ADDERALL XR is the leading brand in the US ADHD market with an average market share of 26% during the six months to June 30, 2007 (2006: 26%). US ADHD market growth of

SOURCE Shire plc
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