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Hurel Corporation Launches Cell-Based In Vitro Testing Product Suite, Milestone in Movement Away from Use of Live Animals in Drug and Toxicity Testing
Date:7/16/2013

NORTH BRUNSWICK, N.J., July 16, 2013 /PRNewswire/ -- Hurel Corporation ("Hurel"), a world-leading provider of advanced artificial tissue constructs and microfluidic cell-based assay platforms, today announced the commercial launch of its innovative in vitro product suite utilizing liver cells of the rat, dog and human species.  The announcement coincided with Hurel's Scientific Advisory Board Chairman Dr. Leslie Z. Benet's presentation of data generated using Hurel's products, which he gave at The Boston Society's HT-ADME 2013 conference, held today at the Broad Institute in Cambridge, Massachusetts.  The commercial availability of the Hurel products marks a milestone in the transition away from the use of live animals in drug and toxicity testing, towards new cell-based technologies that can substitute for and deliver more usefully predictive results than animal-based testing often can.

Hurel's cell-based products, respectively named HμRELHuman™, HμRELDog™, and HμRELRat™, are made from actual liver cells derived from the human, dog, or rat species.  The cells, which have previously been cryopreserved, are reconstituted and restored to functionality in Hurel's laboratories.  Formulated as a "co-culture" of two different, naturally occurring types of cells found in the liver, Hurel's products are distinctive for their high metabolic competency and responsiveness, the stability of their response levels day after day, and their long-lived endurance.  These attributes together enable researchers to perform kinds of experiments that may require a week or multiple weeks to carry out, cannot be completed in the limited span of days or hours afforded by the in vitro products in wide use today, and thus have frequently been conducted in live animals up until now. 


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Prepared by multi-temperature ethanol fractionation with extensive charcoal treatment and dialysis.• Assay: ≥ 95 % (HPCE)• pH ~5.2 (10 mg/mL in 0.15 M NaCl)...
Collected from animals that are 16 to 18 months old. Sterile, Cell culture tested, ID clarifier: USA Origin...
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