Navigation Links
Human brains share a consistent genetic blueprint and possess enormous biochemical complexity
Date:9/19/2012

Scientists at the Allen Institute for Brain Science reported in the latest issue of the journal Nature that human brains share a consistent genetic blueprint and possess enormous biochemical complexity. The findings stem from the first deep and large-scale analysis of the vast data set publicly available in the Allen Human Brain Atlas.

The results of this study are based on extensive analysis of the Allen Human Brain Atlas, specifically the detailed all-genes, all-structures survey of genes at work throughout the human brain. This dataset profiles 400 to 500 distinct brain areas per hemisphere using microarray technology and comprises more than 100 million gene expression measurements covering three individual human brains to date. Among other findings, these data show that 84% of all genes are expressed somewhere in the human brain and in patterns that are substantially similar from one brain to the next.

"This study demonstrates the value of a global analysis of gene expression throughout the entire brain and has implications for understanding brain function, development, evolution and disease," said Ed Lein, Ph.D., Associate Investigator at the Allen Institute for Brain Science and co-lead author on the paper. "These results only scratch the surface of what can be learned from this immense data set. We look forward to seeing what others will discover."

Key Findings

The results of this study show that, despite the myriad personalities and cognitive talents seen across the human population, our brains are more similar to one another than different. Individual human brains share the same basic molecular blueprint, and deeper analysis of this shared architecture reveals several further findings:

  • Neighboring regions of the brain's cortex the wrinkly outer rind are more biochemically similar to one another than to more distant brain regions, which has implications for understanding the development of the human brain,
    '/>"/>

Contact: Steven Cooper
press@alleninstitute.org
646-358-2765
Allen Institute for Brain Science
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. PROLOR Biotech To Present Data On Its Long-Acting Human Growth Hormone At International NeuroEndocrine Meeting
2. Preclinical data shows 100 percent prevention and treatment of influenza with engineered human antibody
3. Millions of DNA switches that power human genomes operating system are discovered
4. Human Genome Decoder and Artificial Life Creator, J. Craig Venter to Speak at "The Atlantic Meets the Pacific"
5. MO BIO Laboratories, Inc. Becomes Exclusive Sponsor Of Natures Human Microbiota Special
6. Global water sustainability flows through natural and human challenges
7. Oncobiologics, Inc. Announces a Collaboration Agreement with XOMA Corporation to Utilize XOMAs Fully Human Antibody Libraries for Their Discovery Platform
8. Published Findings In Human Gene Therapy Methods Journal Demonstrate Cardiums New Catheter-Based Method Significantly Boosts Gene Delivery To The Heart
9. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
10. Chemical makes blind mice see; compound holds promise for treating humans
11. HemoShear Partners with Expression Analysis (EA) to Develop a Human Drug-Induced Vascular Response Database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/15/2014)... The redesigned ActiGraph Link expands upon ... measurement platform with a rich feature set that ... new channels of sensor data captured by a ... Smart technology, the ActiGraph Link supports wireless heart ... ActiGraph’s cloud-based Study Admin platform, giving academic and ...
(Date:11/15/2014)... 2014 The "Operating Room Management ... by Application (Perioperative, Preoperative, operating room Scheduling), by ... - Global Forecast to 2019.” defines and segments ... and forecast of value by product, such as ... this, the value and volumes of operating room ...
(Date:11/15/2014)... LONDON , Nov. 14, 2014 Algenol Biofuels ... 6th at the Oceanographic Museum of Monaco ... CleanEquity Monaco is an annual invitation-only event hosted by ... investment bank. Other partners and sponsors include ... Foundation, Covington & Burling, Cranfield University, PR Newswire, the Monte-Carlo ...
(Date:11/12/2014)... November 12, 2014 The “Pen Needles ... 10mm, and 12mm), Therapy (Insulin, Growth Hormones, Glucagon-like peptide) ... & Global Forecast to 2019”analyzes and studies the major ... 101 market data tables and 51 figures spread through ... by Type (Standard and Safety), by Needle Length (4mm, ...
Breaking Biology Technology:ActiGraph Launches GT9X Link Activity Monitor 2Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 2Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 3Operating Room Management Market Worth $4,551.1 Million by 2019 - New Report by MarketsandMarkets 4Algenol Biofuels Selected to Present at CleanEquity Monaco 2015 2Pen Needles Market worth $2,105 Million by 2019 - New Report by MarketsandMarkets 2Pen Needles Market worth $2,105 Million by 2019 - New Report by MarketsandMarkets 3Pen Needles Market worth $2,105 Million by 2019 - New Report by MarketsandMarkets 4
... Generex Biotechnology Corporation (Nasdaq: GNBT, www.generex.com ) announced ... to the Company and a member of the Company,s ... of the reverse stock split proposal being considered at ... "Having been intimately involved in the drug development world ...
... remote wave sensing by a team of Rensselaer Polytechnic ... chemical, biological agents and illegal drugs from a distance ... terahertz (THz) wave technology, has great potential for homeland ... clothing and packaging materials and can identify immediately the ...
... Recently, academic debate has been swirling around the existence ... of phenomena, including photosynthesis, the process by which organisms ... suggested that entanglement (the quantum interconnection of two or ... separated in physical space) could be occurring in the ...
Cached Biology Technology:Generex Provides Additional Reverse Stock Split Information for the Consideration of Stockholders 2Generex Provides Additional Reverse Stock Split Information for the Consideration of Stockholders 3Generex Provides Additional Reverse Stock Split Information for the Consideration of Stockholders 4A revolutionary breakthrough in terahertz remote sensing 2
(Date:11/3/2014)... Research and Markets has announced the addition of a ... to their offering. This report describes ... started to play an important role in the practice of ... bone marrow transplants. Role of cells in drug discovery is ... of medical practice. Stem cells are discussed in ...
(Date:11/2/2014)... month,s issue of Physics World , James Dacey ... "valley of death" to take their innovations from the ... the gruelling challenge facing all start-up companies as they ... physicists because of two main factors: physics-based inventions are ... often turn out to be a lot more complicated ...
(Date:10/31/2014)... received two major government grants totaling nearly $28 million. ... to continue two major foci of study, one involving ... precision medicine. , The first, a combined grant from ... National Institute for Mental Health for $16.5 million, will ... CEGS. , The second grant, for $11.3 million, is ...
Breaking Biology News(10 mins):Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 2Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 3The 'valley of death' facing physics start-ups 2Transforming 'big data' into knowledge 2Transforming 'big data' into knowledge 3
... State University and Diversa Corporation have discovered that the smallest ... structure, of any independent cell - and yet it dominates ... die, and plays a huge role in the cycling of ... not always better. , In a publication today in the ...
... team of international scientists leaves today on a month-long ... of Southwest China, an extension of the great Himalayan ... a scientific and cultural journey to explore one of ... expedition begins today with a month-long exploration in China ...
... to a new analysis of more than 400 years of ... river basins. , By using data from tree rings, University ... rivers fluctuated in synchrony during periods of severe drought. The ... and covers waterways from the states of Arizona, Colorado, New ...
Cached Biology News:Microbe has huge role in ocean life, carbon cycle 2Team of international scientists departs today to discover the unknown in China's Himalayan region 2Team of international scientists departs today to discover the unknown in China's Himalayan region 3Past droughts geographically widespread in the West, according to tree-ring data 2Past droughts geographically widespread in the West, according to tree-ring data 3
All serum is collected from adult animals aged 6 months or older. Certified U.S. orgin. Pricing: $35/unit for 1 - 10 units...
3'-O-Methylguanosine 5'-Triphosphate, Sodium, 1 umol. Category: Nucleotides & Enzymes & Biochemicals, Nucleotides, Additional Nucleotide Products....
Porcine Serum Available Anticoagulants: N-02: Citrate N-04: Heparin (Na) N-06: K2EDTA N-08: Potassium Oxalate N-10: EDTA (Na) N-03: Alsevers N-05: ACD N-07: CPD N-09: K3EDTA N-11...
... adult normal paraffin tissue array is ... proteins of interest in extensive panels ... Rat brain, heart, kidney, liver, lung, ... arrayed on positively charged glass slide. ...
Biology Products: