Navigation Links
How to mend a broken heart: Advances in parthenogenic stem cells

Parthenogenesis is a form of asexual reproduction during which unfertilized eggs begin to develop as if they had been fertilized. It occurs naturally in many plants and a few invertebrate (some bees, scorpions, parasitic wasps) and vertebrate animals (some fish, reptiles, and amphibians), but does not occur naturally in mammals. In 2007, researchers were able to chemically induce human egg cells to undergo parthenogenesis. The resulting parthenogenote has properties similar to an embryo, but cannot develop further. In this issue of the Journal of Clinical Investigation, Wolfram Zimmerman and colleagues at Georg-August-Universitt Gttingen in Gttingen, Germany, demonstrated that cells from the parthenogenote function as embryonic stem cells and maintain the capacity to develop into different types of tissue. Further, they used parthenogenic stem cells to make cardiomyocytes and engineered heart muscle (myocardium) that exhibited the structural and functional properties of normal myocardium. The engineered myocardium could then be used to engraft the mice that had contributed the eggs for parthenogenesis. These studies demonstrate that parthenogenic stem cells can be used for tissue engineering. In a companion commentary, Michael Schneider of the Imperial College of London discusses how these findings could impact the development of cell replacement therapies.

Contact: Jillian Hurst
Journal of Clinical Investigation

Page: 1

Related biology technology :

1. Mending a broken heart -- with a molecule that turns stem cells into heart cells
2. Genedata Screener for HCS Advances Phenotypic Screening
3. Join Cato BioVentures and Cancer Advances at Biotech Showcase 2013 & J.P. Morgan 31st Annual Healthcare Conference
4. National MS Society Reports Sweeping Advances Made in MS Research in 2012
5. Avelas Biosciences Closes $7.65 Million Series A, Advances Real-Time Tumor Visualization Technology Toward Development
6. Premier Biomedical Successfully Advances Cancer Research
7. H3 Biomedicine Expands Cambridge Facilities, Doubles Employee Base as Scientific Program Advances
8. Computer memory could increase fivefold from advances in self-assembling polymers
9. Collegiate Inventors Honored for Innovative Science and Technology Advances
10. VisionGate Reports Advances In Its Cell-CT(TM) Automated 3D Cell Analysis Platform At ASC 2012 Scientific Meeting
11. New Annual US$3 Million Fundamental Physics Prize Recognizes Transformative Advances in the Field
Post Your Comments:
(Date:6/27/2016)... 27, 2016  Alex,s Lemonade Stand Foundation (ALSF), a ... will open a state-of-the-art bioinformatics lab, using ,big data, ... announcement comes as Liz Scott , co-executive director ... Moonshot Summit in Washington, D.C. , ... participant and advocate of pediatric cancer research and awareness. ...
(Date:6/27/2016)... June 27, 2016  Global demand for enzymes ... through 2020 to $7.2 billion.  This market includes ... cleaning products, biofuel production, animal feed, and other ... and biocatalysts). Food and beverages will remain the ... increasing consumption of products containing enzymes in developing ...
(Date:6/27/2016)... GUELPH, ON , June 27, 2016 /PRNewswire/ - BIOREM ... it has been advised by its major shareholders, Clean ... LP, United States based venture ... common shares of Biorem (on a fully diluted, as ... for the disposition of their entire equity holdings in ...
(Date:6/27/2016)... 2016  Sequenom, Inc. (NASDAQ: SQNM ), ... through the development of innovative products and services, announced ... United States denied its petition to review ... Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") are not ... the Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories ...
Breaking Biology Technology:
(Date:6/27/2016)... , June 27, 2016 Research and Markets ... America 2016-2020" report to their offering. ... North America to grow at a CAGR of 12.28% ... prepared based on an in-depth market analysis with inputs from industry ... over the coming years. The report also includes a discussion of ...
(Date:6/22/2016)... American College of Medical Genetics and Genomics was once again ... of the fastest-growing trade shows during the Fastest 50 Awards ... Las Vegas . Winners are ... of the following categories: net square feet of paid exhibit ... 2015 ACMG Annual Meeting was ranked 23 out of 50 ...
(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
Breaking Biology News(10 mins):