Navigation Links
Heptares Achieves All Research Milestones and Receives Milestone Payment From GPCR Drug Discovery Agreement With Takeda
Date:4/29/2013

WELWYN GARDEN CITY, England and BOSTON, April 29, 2013 /PRNewswire/ --

Heptares Therapeutics, the leading GPCR drug discovery and development company, announces it has achieved all milestones in its collaboration with Takeda Pharmaceutical Company. By achieving these milestones, Heptares will receive a significant payment from Takeda, under the terms of the agreement signed by the two companies in 2011.

The agreement is focused on a single GPCR target nominated by Takeda that, until now, has proved intractable to rational drug discovery efforts due to its instability when removed from the cell membranes and the resulting lack of insight into its structure. Over the course of the collaboration Heptares has leveraged its structure-based drug design (SBDD) approach to GPCRs and proprietary technologies to generate the first-ever stabilised form of the target in a clinically relevant conformation enabling a series of novel lead candidates against the target to be designed.

Tetsuyuki Maruyama , General Manager Pharmaceutical Research Division, Takeda said: "We are impressed with the efficiency and results from this partnership with Heptares. In achieving these milestones, the Heptares team has demonstrated its ability to design new, high-quality small molecules to a previously challenging GPCR target. We look forward to continuing our partnership and taking these leads forward into pre-clinical development."

"Our partnership with Takeda provides an excellent validation of our GPCR-focused structure-based drug design approach and capabilities," said Malcolm Weir , CEO of Heptares. "We see similar good progress in our other partnerships where to date we have hit every milestone. This success, in turn, provides us with an important source of capital, which has enabled us to build an impressive proprietary pi
'/>"/>

SOURCE Heptares Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Heptares Grants Shire an Exclusive Worldwide Licence to Develop and Commercialise Novel Drug Candidate for CNS Disorders
2. Heptares Solves First Family B GPCR Structure
3. Heptares to Present at BIO-Europe 2012
4. Heptares to Moderate Panel on Rare Diseases at BBC New York CEO Meeting (13-14 February)
5. Heptares to Present at Upcoming Scientific and Biotech Industry Conferences
6. GenVec Achieves Second Milestone in Collaboration
7. AtheroNova Achieves Milestone in Initiating First Shipment of AHRO-001
8. RayBiotech, Inc. Achieves Both GMP- and GLP-Compliance and Announces New Dedicated Services Laboratory
9. TriCore Solutions Achieves SAP Gold Partner Status
10. Rafarma Pharmaceuticals, Inc. Achieves Full Certification
11. Idem Translations Achieves ISO 13485:2003 Certification
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... 2015 DryLet, LLC a biotechnology ... such as animal waste reduction, bioremediation, wastewater treatment, ... wastewater treatment plants and restaurant kitchen settings, announced ... National Restaurant Association’s NRA Show 2015, in Chicago, ... the company will be available to share information ...
(Date:4/24/2015)... BOSTON , April 24 , 2015 /PRNewswire/ ... leading global biopharmaceutical services provider, today announced that Partnerships ... Senior Director, Product Management, the 2015 Clinical Innovator of ... the product development team for the Company,s Perceptive MyTrials ... accepting the award Thursday night during the 2015 Partnership ...
(Date:4/23/2015)... , April 23, 2015 /CNW/ - A new ... packaging award from North America,s ... Competitor Comparison won Silver in the "Sustainability, service" ... The Brandcheck "Competitor Comparison" is a service ... North American and Global peers. This benchmarking process ...
(Date:4/23/2015)... Follow us on LinkedIn ... of genetic tests that determine individual susceptibility to ... Huntington's disease, and Alzheimer's disease. Predictive diagnostics are ... interaction in diseased tissue/cells to understand and determine ... response to treatment, such as in the numerous ...
Breaking Biology Technology:DryLet to Showcase Bio-React at the National Restaurant Association’s NRA Show 2015 May 16-19, 2015 in Chicago, Illinois 2PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 2PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 3PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 4PAREXEL Honored With 2015 Clinical Innovator Of The Year Award From Partnerships In Clinical Trials 5Increasing Disease Prevalence & Focus on Preventive Healthcare Drive the Predictive Diagnostics Market, According to a New Report by Global Industry Analysts, Inc. 2Increasing Disease Prevalence & Focus on Preventive Healthcare Drive the Predictive Diagnostics Market, According to a New Report by Global Industry Analysts, Inc. 3
... 500 attendees are,already slated to attend Pharma ChemOutsourcing ... conference & exhibition continues to attract large numbers ... plus increasingly,dozens of mid-sized and smaller biotech companies. ... , Dr. Stefan Loren of Perceptive Life ...
... DSM Biologics and MorphoSys,AG (Frankfurt Stock Exchange: ... signing of a Biopharmaceutical Manufacturing Agreement,covering process ... is a,fully human HuCAL(R) antibody, directed against ... multiple myeloma. DSM Biologics will manufacture,MOR202 in ...
... August 12, - Major Threat Treatable With ... Models, An internationally renowned avian influenza expert ... by his,research team. This study demonstrated impressive efficacy ... and prevention of,H5N1, H1N1 and H3N2 in a ...
Cached Biology Technology:Stunning Attendance for ChemOutsourcing Show on September 8-9 in Long Branch, NJ 2DSM Biologics and MorphoSys AG to Manufacture Fully Human Antibody 2DSM Biologics and MorphoSys AG to Manufacture Fully Human Antibody 3Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic 2Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic 3Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic 4
(Date:3/24/2015)... NexID Biometrics LLC, whose spoof-mitigation technology boosts protection ... beginning of shipments of version 2.0 of its industry ... in Potsdam, N.Y. , is making ... here today at the Walter E. Washington Convention Center. ... boosts the accuracy rate range to 96.5 to 99.5 ...
(Date:3/23/2015)... 2015  In the 2014 fiscal year, irs.gov recorded ... This figure accounts for a fraction of the estimated ... Report, exceeds $11 billion globally. The polygraph has traditionally ... has occurred. Investor Mark Saint Juste along ... Paolella partnered to administer the test in a ...
(Date:3/20/2015)... , March 20, 2015 NXT-ID, Inc. ... biometric authentication company focused on the growing mobile commerce ... wallet is one of the products featured in 2015 ... 20th at 11:00 PM EST on the DIY Network. ... Las Vegas , site of the ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3
... specific types and conditions of dung has been given substantial ... dung from exotic mammals found on game farms or rewilding ... : Scarabaeidae ) Attraction to Native and Exotic Mammal ... Environmental Entomology , Sean D. Whipple, a postdoctoral research associate ...
... that lived within Arctic latitudes approximately 70 million years ... migrating to more southern latitudes, a recent study by ... Nature and Science in Dallas and Temple University has ... Perennial Polar Residents," in the April issue of the ...
... /PRNewswire-iReach/ -- Global Information Inc. is pleased ... research reports from Global Industry Analysts, available immediately, which ... reagents, and electrophoresis equipment and supplies markets coming out ... Technology: A Global Strategic Business Report ...
Cached Biology News:Exotic manure is sure to lure the dung connoisseur 2Duck-billed dinosaurs endured long, dark polar winters 2Duck-billed dinosaurs endured long, dark polar winters 3New Biotech and Pharmaceutical Market Research from Global Information Inc Forecasts Strong Growth Coming Out of Recession 2New Biotech and Pharmaceutical Market Research from Global Information Inc Forecasts Strong Growth Coming Out of Recession 3New Biotech and Pharmaceutical Market Research from Global Information Inc Forecasts Strong Growth Coming Out of Recession 4
... A self-contained work area that will help ... UV bulbs irradiate the work area prior ... DNA will be amplified. Containment features reduce ... hood has acrylic windows for a clear ...
...
... Each glass slide in this ... 722 antibodies in triplicate, for a ... few house-keeping proteins as internal control. ... processes,such as angiogenesis, apoptosis, cell cycle ...
...
Biology Products: