Navigation Links
Heptares Achieves All Research Milestones and Receives Milestone Payment From GPCR Drug Discovery Agreement With Takeda
Date:4/29/2013

WELWYN GARDEN CITY, England and BOSTON, April 29, 2013 /PRNewswire/ --

Heptares Therapeutics, the leading GPCR drug discovery and development company, announces it has achieved all milestones in its collaboration with Takeda Pharmaceutical Company. By achieving these milestones, Heptares will receive a significant payment from Takeda, under the terms of the agreement signed by the two companies in 2011.

The agreement is focused on a single GPCR target nominated by Takeda that, until now, has proved intractable to rational drug discovery efforts due to its instability when removed from the cell membranes and the resulting lack of insight into its structure. Over the course of the collaboration Heptares has leveraged its structure-based drug design (SBDD) approach to GPCRs and proprietary technologies to generate the first-ever stabilised form of the target in a clinically relevant conformation enabling a series of novel lead candidates against the target to be designed.

Tetsuyuki Maruyama , General Manager Pharmaceutical Research Division, Takeda said: "We are impressed with the efficiency and results from this partnership with Heptares. In achieving these milestones, the Heptares team has demonstrated its ability to design new, high-quality small molecules to a previously challenging GPCR target. We look forward to continuing our partnership and taking these leads forward into pre-clinical development."

"Our partnership with Takeda provides an excellent validation of our GPCR-focused structure-based drug design approach and capabilities," said Malcolm Weir , CEO of Heptares. "We see similar good progress in our other partnerships where to date we have hit every milestone. This success, in turn, provides us with an important source of capital, which has enabled us to build an impressive proprietary pi
'/>"/>

SOURCE Heptares Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Heptares Grants Shire an Exclusive Worldwide Licence to Develop and Commercialise Novel Drug Candidate for CNS Disorders
2. Heptares Solves First Family B GPCR Structure
3. Heptares to Present at BIO-Europe 2012
4. Heptares to Moderate Panel on Rare Diseases at BBC New York CEO Meeting (13-14 February)
5. Heptares to Present at Upcoming Scientific and Biotech Industry Conferences
6. GenVec Achieves Second Milestone in Collaboration
7. AtheroNova Achieves Milestone in Initiating First Shipment of AHRO-001
8. RayBiotech, Inc. Achieves Both GMP- and GLP-Compliance and Announces New Dedicated Services Laboratory
9. TriCore Solutions Achieves SAP Gold Partner Status
10. Rafarma Pharmaceuticals, Inc. Achieves Full Certification
11. Idem Translations Achieves ISO 13485:2003 Certification
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/13/2014)... CHARLOTTE, N.C. (PRWEB) December 13, 2014 ... (UNC Charlotte) spin-out company has changed its name to ... more accurate representation of where we are today,” said ... “We’ve extended our platform’s applications beyond breast cancer diagnostics ... is a reflection of that evolution.” , Founded in ...
(Date:12/13/2014)... 2014 The DNA Microarray market ... and is expected to grow at a CAGR ... through the TOC of the DNA Microarray for ... segments, with help of various tables and figures. ... Microarray market consists of instrument, consumables, and services, ...
(Date:12/13/2014)... December 13, 2014 According to population ... people between now and 2030." If a population explosion ... seventh most populous state in the country. , To ... at the Future of North Carolina Forum on December ... we have the necessary infrastructure in place? Enough clean ...
(Date:12/13/2014)... , Dec. 11, 2014 Research and Markets ... addition of the "Glucose Sensors: the Next ... http://photos.prnewswire.com/prnh/20130307/600769 The ... designs is giving hope for a better future ... monitors that can measure glucose levels accurately and ...
Breaking Biology Technology:CanDiag Inc. Expands Product Scope Under a New Name: OncoTab, Inc. 2DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 2DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 3DNA Microarray Market Is Expected to Grow at a CAGR of 15.2% from 2014 to 2019 - A Report by MicroMarket Monitor 4North Carolina Chamber of Commerce: Asking Questions & Gathering Answers with a Futurist 2Glucose Sensors: the Next Generation 2Glucose Sensors: the Next Generation 3
... - Based on initial response, it looks as if ... misnomer for the latest group of former Cray and SGI ... company. , ,The Inver Grove Heights, Minn.-based business, with ties ... aggregation mechanism as a breakthrough product for Apple Computers enterprise ...
... , a maker of molecular diagnostic products, recently announced ... provides clinical trial laboratories with access to a broad ... gene. , ,The panel is a pharmacogenetic testing solution ... custom assay panels. The panel is being used to ...
... , a Madison-based provider of Internet and desktop tools for ... and implement a ground-breaking online voting mechanism for the ... from an industry often considered conservative, ACM announced it will ... its annual awards show in May. , ,Using Broadjams technology, ...
Cached Biology Technology:Former SGI/Cray Team Develops Products for G5 Platform 2Former SGI/Cray Team Develops Products for G5 Platform 3Third Wave Releases Gene Test 2
(Date:12/11/2014)... , Dec. 10, 2014  That blood pressure plays a ... while. Hypertension – the medical term for high blood pressure ... 1800s, and the inflatable cuff that,s used in measuring blood ... mean there,s nothing new about hypertension, its triggers and its ... about the condition and the best ways to treat it. ...
(Date:12/10/2014)... NEW YORK , Dec. 8, 2014 You,ve ... online banking account but can,t remember your password, site key ... birthday? Who was your first grade teacher? ... launches the app that will finally put an ... PINs – 1U TM . 1U leverages a ...
(Date:12/10/2014)... Forest Baptist Medical Center today announced plans for a ... Funding for this $50 million capital project is part ... launched next summer. The medical education ... R.J. Reynolds Tobacco Company complex, adjacent to 525@vine in ... plans to be ready to welcome medical students in ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... 19th conference of the International Society for Sexually Transmitted ... in Quebec City, Canada. The world,s foremost conference ... 1,200 scientists from every continent to discuss the most ... and treatment; emerging threats in bacterial STDs; major intervention ...
... invented a new technology that can inexpensively render ... yes, even diapers, intimate apparel and athletic wear, ... inexpensive anti-microbial technology works on natural and synthetic ... manufacturing process or at home, and it doesn,t ...
... - Researchers are developing new technologies that combine ... and tiny particles such as bacteria, viruses and ... drug manufacturing to food safety. The technologies ... "lab-on-a-chip" applications, or miniature instruments that perform measurements ...
Cached Biology News:New UGA technology makes textiles permanently germ-free; targets health care-associated infections 2New UGA technology makes textiles permanently germ-free; targets health care-associated infections 3Laser, electric fields combined for new 'lab-on-chip' technologies 2Laser, electric fields combined for new 'lab-on-chip' technologies 3
Edited by P.J. Delves (1997) An up-to-date review of antibody-raising technologies, this volume provides researchers with immediate access to the protocols they require every day....
... The product contains 5 ... coated with the monoclonal BerEP4 ... EpCAM (epithelial cell adhesion molecule). ... samples of 2 x 10e7 ...
Superior homology search software - in all the flavours of blast, with increased sensitivity and speed. Free windows version for academic use....
Full service including gene cloning, protien expression and purification of 1 liter culture....
Biology Products: