Navigation Links
Heptares Achieves All Research Milestones and Receives Milestone Payment From GPCR Drug Discovery Agreement With Takeda
Date:4/29/2013

WELWYN GARDEN CITY, England and BOSTON, April 29, 2013 /PRNewswire/ --

Heptares Therapeutics, the leading GPCR drug discovery and development company, announces it has achieved all milestones in its collaboration with Takeda Pharmaceutical Company. By achieving these milestones, Heptares will receive a significant payment from Takeda, under the terms of the agreement signed by the two companies in 2011.

The agreement is focused on a single GPCR target nominated by Takeda that, until now, has proved intractable to rational drug discovery efforts due to its instability when removed from the cell membranes and the resulting lack of insight into its structure. Over the course of the collaboration Heptares has leveraged its structure-based drug design (SBDD) approach to GPCRs and proprietary technologies to generate the first-ever stabilised form of the target in a clinically relevant conformation enabling a series of novel lead candidates against the target to be designed.

Tetsuyuki Maruyama , General Manager Pharmaceutical Research Division, Takeda said: "We are impressed with the efficiency and results from this partnership with Heptares. In achieving these milestones, the Heptares team has demonstrated its ability to design new, high-quality small molecules to a previously challenging GPCR target. We look forward to continuing our partnership and taking these leads forward into pre-clinical development."

"Our partnership with Takeda provides an excellent validation of our GPCR-focused structure-based drug design approach and capabilities," said Malcolm Weir , CEO of Heptares. "We see similar good progress in our other partnerships where to date we have hit every milestone. This success, in turn, provides us with an important source of capital, which has enabled us to build an impressive proprietary pi
'/>"/>

SOURCE Heptares Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Heptares Grants Shire an Exclusive Worldwide Licence to Develop and Commercialise Novel Drug Candidate for CNS Disorders
2. Heptares Solves First Family B GPCR Structure
3. Heptares to Present at BIO-Europe 2012
4. Heptares to Moderate Panel on Rare Diseases at BBC New York CEO Meeting (13-14 February)
5. Heptares to Present at Upcoming Scientific and Biotech Industry Conferences
6. GenVec Achieves Second Milestone in Collaboration
7. AtheroNova Achieves Milestone in Initiating First Shipment of AHRO-001
8. RayBiotech, Inc. Achieves Both GMP- and GLP-Compliance and Announces New Dedicated Services Laboratory
9. TriCore Solutions Achieves SAP Gold Partner Status
10. Rafarma Pharmaceuticals, Inc. Achieves Full Certification
11. Idem Translations Achieves ISO 13485:2003 Certification
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)... DUBLIN , Feb. 27, 2015 Research and Markets ... the "Global Market Report of Trypsin" report to ... Trypsin (CAS 9002-07-7) aims at providing comprehensive data on Trypsin ... Asia , North America , ... trends, pays close attention to Trypsin This report ...
(Date:2/27/2015)... February 27, 2015 The fully ... (Nexera UC) can sequentially analyze up to 48 ... with high-sensitivity detection of targets by mass spectrometry. ... to fulfill the measurement requirements of a wide ... products, drug delivery and search for disease biomarkers, ...
(Date:2/27/2015)... , Feb. 27, 2015  Pfenex Inc. (NYSE ... development of biosimilar therapeutics, today announced that it will ... Marriott Marquis on March 2 nd at 3pm ... on a panel discussing the current state of the ... Biosimilars . For more information on ...
(Date:2/27/2015)... 2015 Cytokinetics, Incorporated (Nasdaq: CYTK) announced ... with patients and health care advocates in the United ... Day®. Rare Disease Day is dedicated to elevating ... the special challenges faced by patients with rare diseases ... proud to stand alongside patients and caregivers representing the ...
Breaking Biology Technology:Global Market Report of Trypsin 2014-2018 2Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 2Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 2Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 4Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 5Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 6
... Brings Growth Opportunities in Transplant Diagnostics, Genetic Testing ... DIEGO, April 8 Gen-Probe (Nasdaq: ... completed its acquisition of Tepnel Life Sciences, plc, ... company based in the United Kingdom, for 27.1 ...
... and Peru , expansion of ... to reduce drug development timelines for biopharmaceutical companies - PRINCETON, ... ) today announced the recent opening of new clinical development ... of the company,s Buenos Aires, Argentina office. These latest ...
... CHICAGO, April 7 The following release is ... http://www.newscom.com/cgi-bin/prnh/20090325/DC89081LOGO ... on the importance of medical science and discovery ... changes are critical to maintaining America,s leadership in ...
Cached Biology Technology:Gen-Probe Completes Acquisition of Tepnel Life Sciences 2Gen-Probe Completes Acquisition of Tepnel Life Sciences 3Gen-Probe Completes Acquisition of Tepnel Life Sciences 4Covance Opens New Clinical Development Offices in Chile, Peru and Expands Argentina Office 2Covance Opens New Clinical Development Offices in Chile, Peru and Expands Argentina Office 3Council for American Medical Innovation Brings U.S. Leaders in Medicine, Biotechnology and Discovery Together in Chicago for 'Best and Brightest Forum on Medical Innovation' 2
(Date:2/23/2015)... OXFORD, Conn. , Feb. 23, 2015 ... ("NXT-ID" or the "Company"), a biometric authentication company focused ... it has filed provisional patent 62114357 for ... With this patent, NXT-ID introduces a new groundbreaking payment ... and the payment account may only be accessed if ...
(Date:2/12/2015)... 12, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce ... 62/113114 for DISTRIBUTED METHOD AND SYSTEM TO ... patent further establishes NXT-ID,s position in the emerging "Internet ... the ability for multiple devices to collaborate with one ...
(Date:2/5/2015)... TRIANGLE PARK, N.C. , Feb. 5, 2015 /PRNewswire/ ... a specialist logistics company and has launched a new ... only Clinical Logistics Organization (CLO).  The new campaign focuses ... emphasis on patient, protocol and shipments. The ... First , aligns Marken,s priorities with its client,s ...
Breaking Biology News(10 mins):NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 3Marken Launches New Patient-Centric Campaign 2
... Following an intense study of agricultural ecosystems near ... analysis and management of a wide range of ... of McGill University,s Department of Geography, Elena Bennett ... Peterson of the Stockholm Resilience Centre at Stockholm ...
... Gorun, PhD, associate professor of chemistry at New ... was awarded a patent today for a novel ... Perfluoroalkyl Perfluoro-Phthalocyanine Compounds" (US Patent Number 7,670,684) discloses ... new materials are comprised of organic scaffolds with ...
... 2010 In one of the most comprehensive global studies ... from the University of Rhode Island and other institutions has ... driving the success of marine reserves. "We make a ... coral, fish and other aquatic organisms," said Richard Pollnac, URI ...
Cached Biology News:Seeing the hidden services of nature 2NJIT researcher awarded patent for hydrophobic, corrosion-resistant coating 2Scientists find community involvement, not only enforcement, drives success of marine reserves 2
Water Distilled (Gibco™) is membrane filtered and endotoxin screened....
Tissue culture grade....
Tris-Hepes kit of BG-163 & BG-165 (order number BG-166)...
... The Nick Translation System is ideal ... DNA. The Nick Translation System: Provides ... labeled nucleotide incorporation Yields >10 8 ... Includes control DNA to monitor the performance ...
Biology Products: