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Harrington Discovery Institute's Dr. Jonathan Stamler earns AHA Distinguished Scientist Award
Date:11/21/2013

CLEVELAND, Nov. 21, 2013 /PRNewswire/ -- Jonathan Stamler, MD, Director of the Harrington Discovery Institute at University Hospitals (UH) Case Medical Center, has received the 2013 American Heart Association Distinguished Scientist Award at the association's annual conference in Dallas, TX.

(Photo: http://photos.prnewswire.com/prnh/20131121/CL22174)

This prestigious honor, the highest bestowed by the American Heart Association, recognizes individuals whose work has significantly advanced the understanding of cardiovascular disease and stroke. An internationally renowned physician-scientist, Dr. Stamler is recognized for the discovery of a universal mechanism by which the gas nitric oxide affects cellular function in biology.

Nitric oxide controls proteins in the body, helps transport oxygen to tissue and is critical to the physiological function of all organs and tissues, including the heart, nervous system and immune system. Dr. Stamler discovered a process, termed S-nitrosylation, by which nitric oxide attaches to proteins to control cellular function and his and related work has shown that aberrant signaling by S-nitrosylation may underlie the basis of numerous disease conditions, including heart disease, asthma, muscle disorders, and neurological diseases, as well as cancer, infection and aging. His findings anchor the development of new therapeutic approaches for patients with heart and other diseases.

Dr. Stamler is the Director, Harrington Discovery Institute at UH Case Medical Center and is the Robert S. and Sylvia K. Reitman Family Foundation Distinguished Chair in Cardiovascular Innovation at UH Case Medical Center and Case Western Reserve University School of Medicine. He also is Director, Institute for Transformative Molecular Medicine, and Professor of Medicine and Biochemist
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