Navigation Links
Grant to explore better methods for delivering antidotes after chemical attacks
Date:9/20/2013

A new $4.47 million project at the University of North Carolina at Chapel Hill, funded by the Defense Threat Reduction Agency, will help lay the groundwork for developing potentially better ways to deliver antidotes against exposure to chemical weapons. The work could ultimately help both civilian and military populations through the design of precisely engineered particles and microneedle patches that are loaded with a nerve gas antidote that can be easily administered in the event of an attack.

Researchers at UNC will use the PRINT technology, also known as Particle Replication In Non-wetting Templates, to design and optimize the size, shape and composition of particles and microscopic needles that can carry life-saving antidotes to chemical nerve gas. If successful, the application of this technology could make it easier to deliver drugs faster to counteract severe reactions to chemical agents.

"Finding the fastest, most effortless method to administer antidotes during a nerve gas attack can be crucial for saving lives," said Joseph DeSimone, Chancellor's Eminent Professor of Chemistry at UNC and William R. Kenan Jr. Distinguished Professor of Chemical Engineering at N.C. State University and of Chemistry at UNC.

A central part of the five-year project will be to optimize the design attributes of precisely uniform arrays of microneedles, tiny structures that would be incorporated into a patch that can be applied directly to the skin where the microneedles dissolve for rapid absorption of the nerve gas antidote. Once the mode of delivery is optimized, the PRINT technology also allows for large-scale manufacturing of these microneedle patches and other possible antidote systems.

"Every second matters when someone is exposed to a chemical agent, so identifying a way to simply slap a patch onto someone's arm, in an instant, could have a life-saving impact," said DeSimone. "We are trying to find the best way to make the delivery of an antidote easy, effective and widely accessible."

DeSimone, who will lead the project, invented the PRINT technology with his students in 2004. The PRINT technology is licensed to Liquidia Technologies (Research Triangle Park, NC) for the development of a wide range of vaccines and therapeutics. Liquidia was co-founded by DeSimone, also in 2004.


'/>"/>

Contact: Thania Benios
thania_benios@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

Related biology technology :

1. FDA Grants Soligenix Orphan Drug Designation for SGX94 for Treatment of Acute Radiation Syndrome
2. Crowdfunding Expert Kendall Almerico Discusses Scientists Using Crowdfunding to Replace Research Grants
3. Star Scientific Announces Patent Claims to Anatabine Citrate to be Granted by PTO
4. Genia Technologies, Columbia University, and Harvard University Awarded $5.25 Million Grant from NIH to Accelerate the Development of NanoTag DNA Sequencing Technology
5. Hovione: EPO Grants a New Inhaler Patent
6. 5 Washington organizations make joint grant
7. Women in Science Grant Challenges Status Quo Animal Research
8. VolitionRx-led Consortium Awarded euro 780 000 ($1M approx.) Eurostars Grant
9. Wayne State receives National Science Foundation grant for training future nanoengineers
10. UMass Boston Receives $1 Million Grant to Recruit Urban Nurse Leaders
11. VG Energy Chief Scientist Awarded $200,000 AgriLife Grant to Study Lipid Secretion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... 27, 2016 At present, the Biotech ... this space know that volatility is what makes this industry ... ActiveWallSt.com: Synta Pharmaceuticals Corp. (NASDAQ: SNTA ), CTI ... LPTN ), and Heat Biologics Inc. (NASDAQ: ... the technical alerts for these stocks at: ...
(Date:5/26/2016)... 2016 Despite the volatility that continues ... space. Today,s pre-market research on ActiveWallSt.com directs the investor community,s ... RDUS ), Cerus Corp. (NASDAQ: CERS ... Five Prime Therapeutics Inc. (NASDAQ: FPRX ). Register ... http://www.activewallst.com/ On Wednesday, shares in ...
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... Lajollacooks4u has ... and has consistently been rated one of its top attractions. Fortune 500 companies, ... to participate in a unique and intimate team-building experience. , Each event kicks off ...
(Date:5/25/2016)... ... May 25, 2016 , ... The American Medical Informatics Association ... the National Coordinator for Health IT (ONC) outlining a measurement approach to interoperability ... available when and where it was needed. The organization of health informatics professionals ...
Breaking Biology Technology:
(Date:3/15/2016)... York , March 15, 2016 ... market report published by Transparency Market Research "Digital Door Lock ... and Forecast 2015 - 2023," the global digital door lock ... 731.9 Mn in 2014 and is forecast to grow at ... Growth of micro, small and medium enterprises (MSMEs) across the ...
(Date:3/11/2016)... PUNE, India , March 11, 2016 ... to a new market research report "Image Recognition Market ... by Application (Marketing and Advertising), by Deployment Type (On-Premises ... Global Forecast To 2022", published by MarketsandMarkets, the global ... in 2015 to USD 29.98 Billion by 2020, at ...
(Date:3/9/2016)... BEACH GARDENS, Fla. , March 9, 2016 ... identity management authentication and enrollment solutions, today announced ... DigitalPersona ® Altus multi-factor authentication ... IT and InfoSec managers to step-up security where ... Washington, DC . ...
Breaking Biology News(10 mins):