Navigation Links
GeneTex Antibody Company to Launch New Line of Primary Antibodies for the Study of Spindle Assembly
Date:11/29/2011

IRVINE, Calif., Nov. 29, 2011 /PRNewswire/ -- GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is pleased to announce that they will be launching a new line of antibodies against Hice1 and Hec1. Both of these targets are key players in spindle assembly.

(Photo:  http://photos.prnewswire.com/prnh/20111129/LA13485-a)

(Logo:   http://photos.prnewswire.com/prnh/20111129/LA13485LOGO-b)

Hice1 is a novel microtubule-associated protein that is required for the maintenance of spindle integrity and chromosomal stability, and the phosphorylation of Hec1 by Nek2 kinase has been shown to modulate chromosome alignment and signaling of the spindle assembly checkpoint. The interaction between Hec1 and Hice also contributes to mitotic centrosomal microtubule growth for proper spindle assembly.

GeneTex's new product line will include a phospo Ser 55 Hec1 antibody, a non-phospho Ser 55 Hec1 antibody, a phospo Ser 76/77 Hec1 antibody, a non-phospho Ser 76/77 Hec1 antibody, a phospo Ser 165 Hec1 antibody, a non-phospho Ser 165 Hec1 antibody, a phospho Ser 19/20 Hice1 antibody, a non-phospho Ser 19/20 Hice1 antibody, as well as corresponding blocking peptides. A complete listing of Hec1 and Hice1 antibodies is available at http://www.genetex.com/Hec1_Hice1.

"I am thrilled to be working with GeneTex to bring these antibodies to a wider group of researchers," said Dr. Guikai Wu, a researcher from the University of California, Irvine who developed these antibodies and has recently published his results in Molecular and Cellular Biology ("Hice1, a Novel Microtubule-Associated Protein Required for Maintenance of Spindle Integrity and Chromosomal Stability in Human Cells") and Molecular Biology of the Cell ("Hec1 Contributes to Mitotic Centrosomal Microtubule Growth for Proper Spindle Assembly through Interaction with Hice1"). "These are excellent antibodies that have worked in every application that I have tried."

The study of spindle assembly has widespread applications, as this process is critical for efficient mitotic progression and accurate chromosome segregation. Errors in this process often lead to structural and functional aberrations that result in the promotion of segregation errors and aneuploidy, a hallmark of most cancers.

GeneTex will be launching one of the largest collections of Hec1 and Hice1 antibodies that have been validated for western blotting, immunofluorescence (ICC/IF), immunohistochemistry (IHC) and other applications. Almost all of the antibodies in the line are antigen-affinity purified, which results in higher quality antibodies for research. GeneTex will also be offering smaller-sized vials of their zebrafish antibodies, allowing researchers the flexibility to try new antibodies at a much lower cost.

For additional information on GeneTex's new line of Hec1 and Hice1 antibodies, call toll-free 877-GENETEX (436-3839) or visit http://www.genetex.com/Hec1_Hice1.

About GeneTex:

GeneTex is an antibody company that was founded by scientists in 1997. They strive to produce the highest quality antibodies and reagents. Their primary antibodies and secondary antibodies are created through a process involving extensive research, development and validation.  GeneTex has over 45,000 primary antibodies in its catalog that are all backed by a 100% Satisfaction Guarantee.  

Contact:

GeneTex
877-436-3839
info@genetex.com


'/>"/>
SOURCE Genetex
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. GeneTex Antibody Company to Launch a Line of New Zebrafish Primary Antibodies
2. Ventana Medical Systems, Inc. Receives First FDA 510(k) Clearance for H. pylori Antibody
3. ShangPharma Subsidiary and Jiangsu Hengrui Medicine Partner in Therapeutic Antibody Research and Development
4. Oxford BioMedica Announces 5T4 Antibody Research Collaboration with ImaginAb
5. BioLegend Releases Brilliant Violet 421™ Antibody Conjugates For Advanced Flow Cytometry Applications.
6. Amgen and Xencor Enter Option Deal to Co-Develop Xencors Novel Antibody for Autoimmune Diseases
7. Vaccinex, Inc. Initiates Clinical Trial of Novel Therapeutic Antibody in Cancer Patients With Advanced Solid Tumors
8. Tolerx Initiates Phase 1 Clinical Trial of TRX518, a First-in-Class anti-GITR Antibody for the Treatment of Cancer
9. Alder Biopharmaceuticals Announces That Data From Multiple Studies of ALD518 (BMS945429), an Investigational Antibody Therapeutic in Rheumatoid Arthritis Patients, to be Presented at Annual Meeting of the American College of Rheumatology
10. Armed antibody triggers remissions for Hodgkins lymphoma
11. Micromet to Provide Update on BiTE Antibody Development Programs at Upcoming Medical Conferences
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... ... 23, 2016 , ... ClinCapture, the only free validated electronic ... showcase its product’s latest features from June 26 to June 30, 2016 for ... Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug Information ...
(Date:6/23/2016)... ... June 23, 2016 , ... Velocity Products, a division ... tuned and optimized exclusively for Okuma CNC machining centers at The International Manufacturing ... collaboration among several companies with expertise in toolholding, cutting tools, machining dynamics and ...
(Date:6/23/2016)... , June 23, 2016 ... research report to its pharmaceuticals section with historic ... details and much more. Complete report ... 151 pages, profiling 15 companies and supported with ... http://www.reportsnreports.com/reports/601420-global-cell-culture-media-industry-2016-market-research-report.html . The Global ...
(Date:6/22/2016)... , June 22, 2016 Research and ... Global Markets" report to their offering. ... billion in 2014 from $29.3 billion in 2013. The market is ... of 13.8% from 2015 to 2020, increasing from $50.6 billion in ... projected product forecasts during the forecast period (2015 to 2020) are ...
Breaking Biology Technology:
(Date:4/28/2016)... , April 28, 2016 First quarter 2016: ... up 966% compared with the first quarter of 2015 ... SEK 589.1 M (loss: 18.8) and the operating margin was 40% ... 0.32) Cash flow from operations was SEK 249.9 M ... revenue guidance is unchanged, SEK 7,000-8,500 M. The operating ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/15/2016)... , April 15, 2016  A new ... make more accurate underwriting decisions in a fraction ... timely, competitively priced and high-value life insurance policies ... screenings. With Force Diagnostics, rapid testing ... lifestyle data readings (blood pressure, weight, pulse, BMI, ...
Breaking Biology News(10 mins):