Navigation Links
Galectin-3 Assessed as a Biomarker of Heart Failure: Key Clinical Trial Findings Published by Dove Medical Press
Date:2/7/2013

(PRWEB) February 07, 2013

Research Reports in Clinical Cardiology has published "Galectin-3: clinical utility and prognostic value in patients with heart failure". This review summarizes the key findings of fourteen clinical trials in which Galectin-3 (Gal-3) was assessed as a biomarker of heart failure in more than 16,900 patients. In addition, it provides the most relevant information available about gal-3 biology generated in in vitro and in vivo research.

Gal-3 biology and preclinical studies are reviewed, assessing its value as a biomarker in heart failure (HF). The author of this study evaluates the utility of gal-3 for diagnosis, clinical decision-making, monitoring, and in prediction of outcomes. According to journal editor-in-chief Dr Richard Kones, "While most authorities agree that gal-3 is a promising biomarker in HF, other than the strong predictive relationship with mortality in different patient populations, more work is needed for any of these uses to attain clinical recognition in the form of evidence-based recommendations."

Study author Frank Kramer, Clinical Sciences, agrees, "Since the most recent review on the role of Gal-3 in heart failure was published several years ago and various additional clinical studies assessing its utility for the management of cardiovascular disease were published since that, an update on this topic is urgently needed."

According to Kramer, the carbohydrate binding protein gal-3, which is expressed by cardiac fibroblasts and several other cell types and which can be quantified in serum or plasma samples, is a frequently discussed biomarker to ass
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Astute Medical, Inc. Advancing Next Generation Acute Kidney Injury Biomarkers
2. Biocartis Announces Commercial Launch of a New Biomarker Analysis Platform
3. Caris Life Sciences Enhances Molecular Profiling Service with Addition of ROS1 and MGMT-Methylation Biomarkers
4. Biomarkers: Technological and Commercial Outlook 2012-2022
5. The PROOF Centre of Excellence Partners with OriGene Technologies on Heart & Kidney Transplant Biomarker Program
6. NextGen introduces its first generation of animal biomarker products for development of brain disorder diagnostics
7. Australian Discovered Biomarkers Map Path to New Blood Test for Bowel Cancer
8. Genomic Health and OncoMed Announce Strategic Alliance for Biomarker Research and Discovery Using Next Generation Sequencing
9. Foundation of UMDNJ Receives Grand Challenges Tuberculosis Biomarkers Grant
10. MarketsandMarkets: Global Biomarkers Market worth $25.79 Billion by 2016
11. bioTheranostics Launches Precision Medicine Biomarkers for Tumor Pathway Interrogation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... 2014 /PRNewswire-iReach/ -- Researchers found that ActiveLife Scientific,s ... with bone fragility fracture when today,s standard bone ... are at risk of fracture for reasons that ... test, the DEXA bone density scan.  Study results ... and Mineral Research Annual Conference (ASBMR) in ...
(Date:9/16/2014)... 2014 RENU 28, the world's first and ... available for purchase in Australia and New Zealand in mid-August ... September 16th. The tour will make stops in Brisbane on ... the 18th, Sydney on the 20th, and Melbourne on the ... New Zealand and to educate people about the new product ...
(Date:9/15/2014)... Sept. 15, 2014  FlexTech Alliance today issued ... printed product demonstrators (demos) and a functional electronic ... with pre-proposals due on October 22, 2014 and ... proposals ultimately selected are provided by the US ... cost share by the proposing organization. ...
(Date:9/15/2014)... NC (PRWEB) September 15, 2014 ... developed deep imaging OCT system for the optical device ... The EnvisuTM S4410 SDOCT for Contact Lens ... for standard and high complexity contact lens, IOL structures, ... imaging of a complete contact lens immersed in a ...
Breaking Biology Technology:ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 2ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 3Global Wellness Company Hosts ASEA Australia Tour September 16-22 2FlexTech Alliance Issues 2015 Request for Proposals in Flexible, Printed Electronics 2Bioptigen Introduces Deep Imaging OCT System for Contact Lens Metrology 2
... for Nanotechnology (LCN) have discovered electronic stripes, called ,charge ... that make up a graphitic superconductor. This is the ... and the finding is likely to have profound implications ... scientists believe will play a key role in the ...
... Inc. (NYSE: WPI ) today announced that ... the United States Food and Drug Administration for its ... and 0.02 mg ethinyl estradiol), a generic version of ... in patent litigation with Bayer concerning this product.  ...
... HAYWARD, Calif., Nov. 29, 2011 Metabolex, Inc., ... development of proprietary new medicines for the treatment ... has been recognized in Windhover,s "Top 10 most ... a potential best-in-class treatment for gout that not ...
Cached Biology Technology:Graphene earns its stripes 2Watson's Generic Yaz(R) Receives FDA Approval 2Metabolex Gout Program Recognized in Windhover's Top 10 Most Interesting Projects to Watch 2Metabolex Gout Program Recognized in Windhover's Top 10 Most Interesting Projects to Watch 3
(Date:9/15/2014)... produced naturally across all kingdoms of life and constitute ... range of biological activities. The presence of halogen substituents ... their molecular properties. , One of the ... the late-stage, site-specific incorporation of a halogen atom into ... bond (one of the most inert chemical bonds known ...
(Date:9/15/2014)... new strategic vision document, released today by the ... the long-term goals, objectives, and strategies for the ... over the next five years (2015-2020). In ... activities, to be funded in 2015, will include ... fellowships. , The $500 million, 30-year program ...
(Date:9/15/2014)... that affect hearing and cognitive function may play roles ... and perceive rhythm, pitch, timbre, tone durations, and formal ... BioEssays article explain that extremes in musical aptitude ... the majority of individuals having moderate aptitude. , "This ... to several underlying genes, and it is influenced to ...
Breaking Biology News(10 mins):Pitt chemical biologist finds new halogenation enzyme 2NAS Gulf Research Program announces strategic vision, initial opportunities 2NAS Gulf Research Program announces strategic vision, initial opportunities 3NAS Gulf Research Program announces strategic vision, initial opportunities 4
... propose ever-larger conservation areas in the tropics, ones that ... banding together with their community leaders who ultimately determine ... parts of the world., "When people sacrifice to conserve, ... Christie, University of Washington associate professor of marine affairs ...
... Alexandria, Va. The American Association for Dental ... 2010 AADR Neal W. Chilton Fellowship in Clinical Research ... Meeting & Exhibition in Washington, DC, March 3, 2010. ... and associate director of the Delta Dental of Kentucky ...
... the first-ever data to show that the enzyme calcineurin is ... and that loss of the protein leads to heart problems ... in the Journal of Biological Chemistry as the ... research was led by scientists at Cincinnati Children,s Hospital Medical ...
Cached Biology News:Local social dynamics key to success of tropical marine conservation areas 2Scientists identify critical enzyme in healthy heart function 2
... Dinitro-5,5'-dithiodibenzoic acid , DTNB , Ellman's reagent ... , *CAS-No.: 69-78-3 *Storage: ... with a reactive grouping not present in the ... reagent which will react directly with the product ...
Borrelia Burgdorfen (IgG) -Ab EIA Sample Size: 100 l...
... RNase Inhibitor (patent pending) is a protein ... binds and inhibits the most common and ... 1 and T1. SUPERaseIn can be used ... be problematic. It is ideal for in ...
... Recombinant Ribonuclease Inhibitor is a ... ribonucleases such as RNase A. ... Recombinant Ribonuclease Inhibitor is an ... weight ~52 kDa. RNaseOUT inhibits ...
Biology Products: