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Ernest Mario, Ph.D., Named Chairman of Chimerix, Inc.
Date:2/20/2013

trides to validate its science and IP by advancing CMX001 into Phase 3 and by licensing CMX157 to Merck," said Dr. Mario. "I look forward to working with Ken, the Board and the entire Chimerix team to build upon the company's success to date and to help bring CMX001 to patients who might benefit from it worldwide."

Dr. Mario earned a B.S. in pharmacy at Rutgers University and an M.S. and Ph.D. in physical sciences at the University of Rhode Island.  He is Chairman of the American Foundation for Pharmaceutical Education, a Director of the Gladstone Foundation, and past Chairman of the Duke University Health System.

About Chimerix and CMX001

Chimerix is committed to the discovery, development and commercialization of novel, oral antiviral therapeutics designed to transform patient care in areas of high unmet medical need.  The Company's proprietary lipid technology has given rise to two clinical-stage lipid acyclic nucleoside phosphonates, CMX001 and CMX157, which have demonstrated the potential for enhanced activity and safety in convenient, orally administered dosing regimens. 

Chimerix's lead product candidate, CMX001, is a broad spectrum, oral nucleotide analog lipid-conjugate that blocks replication of double-stranded DNA (dsDNA) viruses, including cytomegalovirus (CMV), adenovirus (AdV), BK virus and herpes simplex virus.  CMX001 has completed Phase 2 clinical development for the prevention of CMV in hematopoietic stem cell transplant (HSCT) recipients.  Chimerix is also conducting a Phase 2 study in HSCT recipients which is evaluating CMX001 as a preemptive therapy for AdV disease, an often-fatal infection which has no approved therapies.  Since 2009, Chimerix has made CMX001 available under expanded access regulations to over 80 transplant centers worldwide for the treatment of over 430 patients with life-threatening dsDNA viral infections.  Chimerix anticipates initiating SUPPRESS, its Pha
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SOURCE Chimerix, Inc.
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