Austin, TX (PRWEB) May 01, 2013
Emergent Technologies, Inc. and portfolio company, Caisson Biotech, LLC, developer of the novel HEPtuneTM drug delivery system, are teaming with Seton Healthcare Family and the research group of Dr. T.J. Milling to modify a therapeutic drug in order to increase its performance and safety and improve patient experience and outcomes. Together they will select a final drug candidate for HEPtune application, design studies for the enhanced drug and subsequently take the HEPtune drug through preclinical, Phase 1 and Phase 2 trials. Seton and Milling’s research team will provide in-kind clinical support.
HEPtune is a novel drug delivery platform being developed by Caisson Biotech that uses naturally occurring heparosan, conjugated to pharmaceutical drugs to enhance the therapeutic properties of these drugs by increasing product half-life, reducing immunogenicity and increasing stability. A key patient benefit of the technology is fewer injections and HEPtune promises to be a safer alternative to polyethylene glycol (PEG), a widely used, polymer-based drug delivery system that has been shown to produce toxicity and other unwanted side effects.
Under the terms of the agreement, Caisson will provide HEPtune technology access and intellectual property rights; procurement and development of the therapeutic drug; and technical support and administration for the duration of the collaboration. Seton will supply the use of hospital facilities and staff necessary to conduct clinical trials, and Milling’s research team will conduct and provide all clinical support and trial data analysis.
Planning for this joint venture began over a year ago, after Caisson signed a multi-million dollar development and licensing agreement with pharmaceutical leader Novo Nordisk.
“Dr. Tom Caven and I began evaluating ways we could work together, leveraging Seton’s infrastructure, the leading enroll
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