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Diagenode Introduces Innovative Bioruptor® Pico for Micro-Volume Chromatin and DNA Shearing
Date:4/4/2013

Denville, NJ (PRWEB) April 04, 2013

Diagenode, Inc., a leading global provider of complete solutions for epigenetics research today announced the launch of the Bioruptor® Pico, an innovative “all-in-one” sonication device for chromatin and DNA shearing. Diagenode’s Bioruptor® sonication devices use Adaptive Cavitation Technology (ACT) to create gentle, focused mechanical stress to shear biological samples in a temperature-controlled environment, highly effective for chromatin shearing, DNA & RNA shearing, cell lysis and tissue homogenization. The Bioruptor® is the most cited line of sonication devices with over 700 peer-reviewed publications.

The new Bioruptor® Pico represents a new breakthrough as an all-in-one shearing system optimized for shearing micro-volumes of 5 µl to larger volumes of up to 2 ml. This wide range enables a large variety of applications such as DNA shearing for next generation sequencing library preparation, RNA shearing, and chromatin shearing. It has been widely noted that shearing is a critical step in a number of applications. For example, the data accuracy from applications such as next generation sequencing library preparation, chromatin immunoprecipitation, and ChIP-seq depends on high-quality sample shearing and fragmentation.

"The Diagenode Bioruptor® Pico has been designed to provide the consistency, yields, and best range of fragment sizes, aspects that are critical for optimal sequencing library preparation such as in ChIP-seq and chromatin shearing” said Didier Allaer, CEO of Diagenode, “We remain committed to the epigenetics market, providing unique epigenetic solutions and innovating our line of shearing devices as the market requires increasingly smaller volumes for shearing.” In addition, the new instrument allows cost-effective shearing with sample multiplexing and simultaneous sonication of 6 to12 samples."

Manuela Saath
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