Navigation Links
Damaged Tissues and Organs Could be Repaired With New Scaffolding Technique
Date:7/16/2013

Cambridge, MA (PRWEB) July 16, 2013

Damaged organs could be repaired in the near future with devices enabled by a manufacturing technique used today for components in mobile phones and other consumer electronics. Researchers at Draper Laboratory and MIT demonstrated a prototype device using this approach under contract to the National Institutes of Health (NIH). The long term goal for the research is to develop implantable, fully functioning artificial tissues and organs.

In an early view article published online by Advanced Materials, Lisa E. Freed, the principal investigator for the project at Draper Laboratory and MIT, and Martin E. Kolewe, a post doctoral associate at MIT, adapted a semi-automated layer-by-layer assembly method commonly used to build integrated circuits in the electronics packaging industry to instead stack porous, flexible, biodegradable elastomer sheets to form three dimensional (3-D) scaffolds on which tissues can be grown. The breakthrough allows researchers to build controlled 3-D pore networks that guide cells to grow in precise patterns, as is seen in highly specialized tissues like heart and skeletal muscle.

Cells in a human heart rely on a variety of spatial and chemical cues to form the hierarchical organization that results in a complete and functional organ. “Function follows form, especially when we try to create artificial tissue,” Kolewe said, explaining that the researchers first identified key structural cues that could guide specific cell growth patterns, and then replicated these cues in their scaffolds to grow specific tissue architectures. The researchers were able to grow contractile heart tissue from rat heart cells using their 3-D scaffolds.

Before this work, researchers intent on growing human tissues lacked the ability to precisely contro
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Black Mold Eats Away the Properties in an NYC Storage Facility, My Cleaning Products Suggests Use of Molderizer to Save Damaged Items
2. New Stem Cell Activating Anti-aging Serums Offer Hope for Damaged Skin
3. Dr. Rongxiang Xu, Owner of Patented Technology to Regenerate Damaged Organs, Announces Lawsuit Against 2012 Nobel Laureate Dr. Shinya Yamanaka
4. Dr. Rongxiang Xu, Patent Owner of Damaged Organ Regeneration, a Top Priority Addressed in the 2013 Presidential State of The Union, Files Lawsuit Against 2012 Nobel Laureate Dr. Yamanaka for Deception
5. Dr. Rongxiang Xu, Patent Owner of Damaged Organ Regeneration, a Top Priority Addressed in the 2013 Presidential State of The Union, Files Lawsuit Against Dr. Yamanaka for Deception
6. New method for producing precursor of neurons, bone and other important tissues from stem cells
7. Precisely engineering 3-D brain tissues
8. Designing interlocking building blocks to create complex tissues
9. New MRI method fingerprints tissues and diseases
10. Findings could be used to engineer organs
11. Microfabrication breakthrough could set piezoelectric material applications in motion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... YORK , Oct. 20, 2014 ... their experimental ZMapp™ antibody therapeutic to fight the ... how difficult and time-consuming the production of pharmaceuticals ... market research publisher said that while some may ... of this compound, those with industry knowledge are ...
(Date:10/20/2014)... Calif. , Oct. 20, 2014 ... that the Company has signed a Notice of ... Regenerative Medicine (CIRM), effective October 1, 2014.  The ... Development payments and the release of additional grant ... CIRM grant award for clinical development of Asterias, ...
(Date:10/20/2014)... October 20, 2014 , A ... disorders and the delivery of care has revealed changing ... worrying inequalities in the provision of healthcare services across ... commissioned by United European Gastroenterology (UEG), have been announced ... public awareness of the burden of GI disorders across ...
(Date:10/20/2014)... -- PureTech , a science and technology ... announced today the closing of a $55 million ... Perpetual, a $120 Billion group of funds. The ... pipeline forward and to advance new healthcare related ... to really go for the big ideas that ...
Breaking Biology Technology:Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6
... Alseres,Pharmaceuticals, Inc. (Nasdaq: ALSE ) ... President and Chief Business Officer of Alseres,Pharmaceuticals, ... 2nd,Annual Therapeutic Area Partnerships in Philadelphia, PA ... an overview on Alseres Regenerative,Therapeutics program. Cethrin(R), ...
... -- WuXi PharmaTech (NYSE:,WX), China,s premier provider of ... been nominated the winner of Deloitte,Technology Fast 50 ... technology,companies in China as recognized by Deloitte Touche ... The Deloitte Technology Fast 50 China program ...
... 18 Sigma-Aldrich (Nasdaq:,SIAL) announced today the ... System. N-TER allows researchers to reproducibly,interrogate gene ... types that,have previously not been considered amenable ... lipid-based siRNA transfection reagents exhibit a number,of ...
Cached Biology Technology:Alseres Pharmaceuticals, Inc. to Present at Windhover's Therapeutic Area Partnerships Conference 2WuXi PharmaTech (NYSE: WX) Wins Both Deloitte Technology Fast 50 China and Deloitte Technology Fast 500 Asia 2Sigma-Aldrich Introduces N-TER Nanoparticle siRNA Transfection System for Delivery of siRNA Into Difficult-to-Transfect Cell Types 2
(Date:10/16/2014)... the bowel lining develops and, in the process, suggested ... The researchers produced evidence that stem cells are responsible ... feature of the bowel lining, and believe these stem ... finding as scientists are still divided on the stem ... Wee Tan and Professor Tony Burgess from the Walter ...
(Date:10/16/2014)... severe respiratory tract infections and worldwide claims the ... VIB and Ghent University have succeeded in developing ... virus infection. , Xavier Saelens (VIB/UGent): "We ... way for the development of a novel approach ... suffering in numerous small children and elderly people." ...
(Date:10/16/2014)... SHELTON, Conn. , October 16, 2014 ... ("NXT-ID" or the "Company"), a biometric authentication company focused ... present its leading edge technologies including Wocket™, the Smart ... Review® (FiRe) Conferenece. FiRe is a leading global conference ... Hosted by Mark Anderson , founder ...
Breaking Biology News(10 mins):Cryptic clues drive new theory of bowel cancer development 2New perspectives for development of an RSV vaccine 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3
... AUSTIN, TexasFrom deep within the genomes of organisms as diverse ... responsible for causing human diseases such as cancer and deafness. ... fact that all life on Earth shares common ancestry, and ... yeast, for example, that humans use to make veins and ...
... for the meeting Experimental Biology 2010 the American ... Society for Biochemistry and Molecular Biology, American Society ... American Society for Pharmacology and Experimental Therapeutics are ... presented April 24-28, at the Anaheim Convention Center. ...
... The general public expects businesses outside the health ... to be involved in health in ways that ... to the Edelman Health Engagement Barometer 2010. Nearly ... that is effectively engaged in health and two-thirds (65 ...
Cached Biology News:Scientists find new genes for cancer, other diseases in plants, yeast and worms 2Selected highlights of the research being presented at the Experimental Biology 2010 meeting 2Selected highlights of the research being presented at the Experimental Biology 2010 meeting 3Selected highlights of the research being presented at the Experimental Biology 2010 meeting 4Global study shows 'health' joins 'green' as business strategy 2Global study shows 'health' joins 'green' as business strategy 3Global study shows 'health' joins 'green' as business strategy 4
... the research-grade spectrofluorometer with a minimum 1 ... ratio 200 or greater for the Raman ... designed to keep in mind in order ... stopped-flow, titration, or anisotropic measurements. ,The FP-6500 ...
... microRNA expression profiling and built on ... on-chip synthesis platform. These microarrays are ... microRNA Expression Profiling Service. ... Microarray contains all known fish microRNAs ...
... microRNA expression profiling and built on ... on-chip synthesis platform. These microarrays are ... microRNA Expression Profiling Service. ... Microarray contains all known virus microRNAs ...
... extends the legendary MSn performance of the ... information through Thermo Scientifics innovations in ion ... is the only mass spectrometer that offers ... Pulsed Q Collision Induced Dissociation (PQD) ...
Biology Products: