MADISON, Wis., Dec 13, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the commercial launch of human iCell® Neurons for use in neuroscience drug discovery, neurotoxicity screens, and other health research. This is the first commercial availability of human neurons, or brain cells, created from induced pluripotent stem (iPS) cells in the quantity, quality, and purity required for life science research.
iCell Neurons exhibit the typical physiological characteristics and responses of the neurons with which we are born. These neurons quickly form connective neuronal networks that are electrophysiologically active, making them useful in a variety of applications commonly used in neuroscience research, including cell viability, ATP production, oxidative stress, neurite outgrowth, electrophysiology, and synaptic neurotransmission assays. CDI's proprietary manufacturing capabilities enable the production of iCell Neurons in industrial quantities with greater than 95% purity.
CDI has successfully engaged in pre-launch collaborations with several pharmaceutical customers for validation testing and establishing disease-relevant neuroscience assays. "We have been working with CDI for some time now and are very impressed with their iCell Neurons, which provide us with a unique model of pure and highly differentiated human neurons showing real potential for measuring functional neurotransmission," said Dr. Pascal Laeng, Head of Molecular and Cellular Pharmacology at Galenea Corp. "The preliminary data are very promising, and we look forward to continued collaboration with CDI to implement iCell Neurons in our high throughput assay of synaptic function."
Dr. Johannes Mosbacher, Director of CNS Electrophysiology, Actelion
|SOURCE Cellular Dynamics International, Inc.|
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