Navigation Links
CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies
Date:4/28/2009

Peptide-based vaccines could prove efficacious for both prophylactic and therapeutic treatments

VIENNA, Va., April 28 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE AMEX: CVM) announced today that preclinical studies have demonstrated that vaccines utilizing its proprietary L.E.A.P.S.(TM) (Ligand Epitope Antigen Presentation System) vaccine technology could potentially induce protection against illnesses such as swine influenza. In pre-clinical studies using mouse models, several different L.E.A.P.S. conjugates focused on different diseases induced protection and disease improvement. In addition, it was recently presented that the L.E.A.P.S. vaccines work on human cells and that the L.E.A.P.S. vaccines are able to induce cellular responses without excessive amounts of proinflammatory cytokines. In the case of prior pandemic influenza, such as the "Spanish Influenza" and more recently in avian flu, patients with stronger immune systems had a greater chance of dying because their immune response was too strong (too many proinflammatory cytokines). A L.E.A.P.S. vaccine may be able to work around that problem. While normally cytokines may play a key role in preventing and treating swine flu, in some cases excessive cytokine amounts may exacerbate disease as it appears that, unlike the normal flu which affects the very young and very old most severely, swine flu may be more like the avian flu which hits people in their prime more severely.

The L.E.A.P.S. technology combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein, to make a vaccine that induces a defined immune response. The Company hopes to commence clinical trials in humans in order to demonstrate that the L.E.A.P.S. vaccine act and stimulate human dendritic cells
'/>"/>

SOURCE CEL-SCI Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease
2. Spherix Shareholders Support Companys Focus on Naturlose, Biotechnology
3. Novel Technology Breaks Through Cancer Pain
4. Amyris Biotechnologies Co-Founder Neil Renninger Named to Technology Reviews Prestigious TR35 List of Top Young Innovators
5. Advanced Cell Technology Announces Proposed Financing
6. Advanced Cell Technologys Dr. Robert Lanza Makes List of 100 Most Inspiring People in the Life-Sciences Industry
7. Operon Biotechnologies and DNA2.0 Announce Co-Marketing and Technology Development Partnership
8. BioMarin Licenses Technology From Leading Cystic Fibrosis Research Laboratory at the University of California, San Francisco
9. Microchip Biotechnologies, Inc. Secures Exclusive License to Use New University of Alberta Technology for Developing Microfluidic Devices
10. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
11. China Technology Announces New Chief Financial Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... July 31, 2014 Today BioSpace , the leading life ... map campaign spotlighting the life sciences community in Illinois ... Kansas , Michigan , Minnesota ... Ohio and Wisconsin . ... percent of all job postings on BioSpace originating in this region in ...
(Date:7/31/2014)... Nearly 20,000 medical professionals and healthcare leaders ... Clinical Lab Expo in Chicago ... diagnostic research and technology that will advance medicine and ... of Wednesday, July 30, more than 19,500 attendees had ... Lab Expo, with more than 10,000 of these attendees ...
(Date:7/31/2014)... reason people over 60 are not donor candidates for ... with time, making the elderly prone to life-threatening infection ... team now has discovered a reason why. , "We ... of blood-forming cells to maintain blood production over time ... that could be restored for rejuvenation therapies," said Emmanuelle ...
(Date:7/31/2014)... Alan Turing, the British mathematician (1912-1954), is famous for ... the 20th century. In 1936 he published a paper, ... first formal concept of a computer algorithm. He next ... designing the machines which cracked the German military codes, ... crucial battles. And in the late 1940,s he turned ...
Breaking Biology Technology:Midwest Biotech Leaders Featured On BioSpace Map 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 3Key to aging immune system is discovered 2A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 2A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 3
... common U.S. laws on research and process labs and ... offer practical compliance solutions, ... with Lab Manager Magazine, will present a Web,conference on laboratory ... online conference will review common U.S. federal laws,pertaining to the ...
... Inc. (Nasdaq: BIOM ),(TSX: BRA) today announced ... Phase II trial of the Stimuvax(R) MUC-1 vaccine ... that Stimuvax,combined with best supportive care (BSC) may ... NSCLC who had either responded or had,stable disease ...
... Inc. (NYSE: CRY ),a biomaterials, medical device ... Lee, executive vice president, chief operating officer,and chief ... present at,the Bear Stearns 20th Annual Healthcare Conference ... Mr. Lee will also present at the First ...
Cached Biology Technology:Sigma-Aldrich and Lab Manager Magazine Present Webinar On Laboratory Environmental, Health and Safety Compliance Strategies 2Sigma-Aldrich and Lab Manager Magazine Present Webinar On Laboratory Environmental, Health and Safety Compliance Strategies 3Stimuvax(R) Phase II data highlight three-year survival results for patients with non-small cell lung cancer 2Stimuvax(R) Phase II data highlight three-year survival results for patients with non-small cell lung cancer 3Stimuvax(R) Phase II data highlight three-year survival results for patients with non-small cell lung cancer 4
(Date:7/31/2014)... tuna movements in the northwestern Atlantic Ocean led by ... at the University of Massachusetts Amherst, found among other ... with pronounced north-south movements from Georges Bank to the ... Cape Hatteras southwest of Bermuda for foraging. , This ... one of the most important commercial tuna species in ...
(Date:7/31/2014)... by the National Science Foundation (NSF), counters a ... atmospheric warming, indicating instead that certain Arctic lakes ... the atmosphere. , The study, published this ... on thermokarst lakes, which occur as permafrost thaws ... fresh water, converting what was previously frozen land ...
(Date:7/31/2014)... By tracing nearly 3,000 genes to the earliest ... Florida scientists have created an extensive "Tree of ... next-generation DNA sequencing. , Among the study,s ... to small moths than to large ones, which ... The study also found that some insects once ...
Breaking Biology News(10 mins):Study of bigeye tuna in Northwest Atlantic uses new tracking methods 2Study of bigeye tuna in Northwest Atlantic uses new tracking methods 3Certain Arctic lakes store more greenhouse gases than they release 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3
... leadership from Massachusetts General Hospital (MGH) researchers has identified ... insulin levels. Two of these novel variants and ... also found to increase the risk of type 2 ... of the same research consortium, associating additional genetic variants ...
... (January 15, 2010) - Latinos are not all the same ... new study by a Columbia University researcher shows key differences ... trying to stem the risk of cardiovascular disease in this ... the new findings published in the January 19, 2009 ...
... PHOENIX, Ariz. Jan. 15, 2009 A scientific ... have identified three kinases, or proteins, that dismantle connections ... associated with Alzheimer,s disease. These findings, the results ... month,s edition of BMC Genomics in a ...
Cached Biology News:New gene variants associated with glucose, insulin levels, some with diabetes risk 2Crucial differences found among Latino populations facing heart disease risks 2Researchers identify proteins that might contribute to memory loss and Alzheimer's disease 2Researchers identify proteins that might contribute to memory loss and Alzheimer's disease 3
... This CLS number is a ... easily match Cornings product number. ... please order under the old ... customer service for assistance. ID ...
Extremely high efficiency packaging extracts useful for transfecting our EpiFOS™ or CopyControl™ Fosmids, or any DNA vector with cos sites. A tremendous value when conpared to the competition...
... simultaneous dual parameter assay for mitochondrial ... activity. Active caspases are detected by ... which are cell-permeable, non-cytotoxic and bind ... the cells. At the same time ...
... cells were cultured in DMEM and harvested at ... to keep the antigens in their native forms, ... are arrayed on a 12-well (5 mm) adhesive ... to enhance cellular attachment and to minimize background ...
Biology Products: