Navigation Links
CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies
Date:4/28/2009

Peptide-based vaccines could prove efficacious for both prophylactic and therapeutic treatments

VIENNA, Va., April 28 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE AMEX: CVM) announced today that preclinical studies have demonstrated that vaccines utilizing its proprietary L.E.A.P.S.(TM) (Ligand Epitope Antigen Presentation System) vaccine technology could potentially induce protection against illnesses such as swine influenza. In pre-clinical studies using mouse models, several different L.E.A.P.S. conjugates focused on different diseases induced protection and disease improvement. In addition, it was recently presented that the L.E.A.P.S. vaccines work on human cells and that the L.E.A.P.S. vaccines are able to induce cellular responses without excessive amounts of proinflammatory cytokines. In the case of prior pandemic influenza, such as the "Spanish Influenza" and more recently in avian flu, patients with stronger immune systems had a greater chance of dying because their immune response was too strong (too many proinflammatory cytokines). A L.E.A.P.S. vaccine may be able to work around that problem. While normally cytokines may play a key role in preventing and treating swine flu, in some cases excessive cytokine amounts may exacerbate disease as it appears that, unlike the normal flu which affects the very young and very old most severely, swine flu may be more like the avian flu which hits people in their prime more severely.

The L.E.A.P.S. technology combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein, to make a vaccine that induces a defined immune response. The Company hopes to commence clinical trials in humans in order to demonstrate that the L.E.A.P.S. vaccine act and stimulate human dendritic cells
'/>"/>

SOURCE CEL-SCI Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease
2. Spherix Shareholders Support Companys Focus on Naturlose, Biotechnology
3. Novel Technology Breaks Through Cancer Pain
4. Amyris Biotechnologies Co-Founder Neil Renninger Named to Technology Reviews Prestigious TR35 List of Top Young Innovators
5. Advanced Cell Technology Announces Proposed Financing
6. Advanced Cell Technologys Dr. Robert Lanza Makes List of 100 Most Inspiring People in the Life-Sciences Industry
7. Operon Biotechnologies and DNA2.0 Announce Co-Marketing and Technology Development Partnership
8. BioMarin Licenses Technology From Leading Cystic Fibrosis Research Laboratory at the University of California, San Francisco
9. Microchip Biotechnologies, Inc. Secures Exclusive License to Use New University of Alberta Technology for Developing Microfluidic Devices
10. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
11. China Technology Announces New Chief Financial Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... , April 1, 2015  Spherix Incorporated (Nasdaq: ... to the fostering and monetization of intellectual property, ... privately held full service global investment bank specializing ... an industry note featuring Spherix. The ... a Senior Analyst at Chardan, was published on ...
(Date:4/1/2015)... , April 1, 2015 ... developing novel biological drugs to treat cancer, viral ... announce the appointment of Christina Coughlin ... responsible for providing medical and regulatory leadership to ... Dr. Coughlin has extensive experience in ...
(Date:3/31/2015)... Materials in Society Lecture Series ... 30 2015   Elsevier , a world-leading ... and publishing home of Materials Today , announced that ... Materials in Society  Lecture Series . The ... International Conference on Materials for Advanced Technologies (ICMAT) ...
(Date:3/31/2015)... SALT LAKE CITY , March 31, 2015 /PRNewswire-USNewswire/ ... second milestone with the selection of ten proposals ... The MCRI is the first patient-led, scientifically validated ... patients. Stage 2 of the MCRI ... "After careful review of a large number of ...
Breaking Biology Technology:Chardan Capital Issues Industry Note Covering Spherix 2Chardan Capital Issues Industry Note Covering Spherix 3Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 2Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 3Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 4Elsevier Materials Science Council Introduces the Materials in Society Lecture Series at the International Conference on Materials for Advanced Technologies (ICMAT) 2Elsevier Materials Science Council Introduces the Materials in Society Lecture Series at the International Conference on Materials for Advanced Technologies (ICMAT) 3Myeloma Crowd Research Initiative Selects 10 High-Risk Multiple Myeloma Proposals For Further Review 2
... Ltd.,(SWX: ARPN) today announced that Dr Jurgen Raths will ... Raths commands extensive,knowledge in the commercialisation of drugs for ... built and lead the European,Critical Care sales, medical and ... At the Annual General Meeting of 7 May, ...
... ,Exelixis, Inc. (Nasdaq: EXEL ) announced today that ... Exelixis, will present at the,Morgan Stanley Global Healthcare Unplugged ... 30, 2008. Dr. Scangos will discuss updates to,the company,s ... be webcast and may be accessed in the Event,Calendar ...
... Inc. (Nasdaq: IDIX ) announced today that ... upcoming Morgan Stanley Global,Healthcare Unplugged Conference on Wednesday, ... Ritz Carlton in Key Biscayne, Florida., The ... can be,accessed under "Calendar of Events" in the ...
Cached Biology Technology:Leadership Change to Enable Arpida to Become a Fully Integrated Pharmaceutical Company 2Leadership Change to Enable Arpida to Become a Fully Integrated Pharmaceutical Company 3Leadership Change to Enable Arpida to Become a Fully Integrated Pharmaceutical Company 4
(Date:4/1/2015)... April 1, 2015   Medisafe ™, the leading ... across iOS and Android smartphones ... biofeedback into the platform to allow patients to track ... the first time, patients will be able to visualize ... impacts important biometrics, such as glucose levels and blood ...
(Date:3/24/2015)... , Mar. 24, 2015 Research and Markets ... the "Global Iris Recognition Market 2015-2019" report ... Global Iris Recognition market to grow at a CAGR ... This report covers the present scenario and the growth ... period 2015-2019. To calculate the market size, the report ...
(Date:3/23/2015)... March 23, 2015   HOYOS Labs , a ... today announced that the Company will demonstrate multiple biometrics-based ... and consumers at Connect:ID on March 23 through 25, ... Labs will highlight the IEEE Biometric Open Protocol Standard; ... and enterprise access control system. BOPS was invented by ...
Breaking Biology News(10 mins):Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... be the impact of the next green revolution on global ... climate change? To what extent can biofuels help make America ... be discussed at the International Annual Meetings of the American ... and Soil Science Society of America (SSSA), Oct. 31-Nov. 3 ...
... NY, October 28, 2010Mary Ann Liebert, Inc. announces the ... area of systems neuroscience, Brain Connectivity . This ... source of cutting-edge basic and clinical neuroscience research aimed ... the brain and how these connections are altered by ...
... by Lupus Research Institute-funded investigator Emily Baechler Gillespie, PhD, at ... clinical laboratory for development and could soon result in a ... to determine when a lupus flare is imminent. ... way to predict when a person with systemic lupus is ...
Cached Biology News:Media alert: Agronomists, crop and soil scientists to convene in Long Beach 2New Brain Connectivity journal captures latest advances in neuroscience research 2New clinical test to predict lupus flares moves closer to the market 2
... (Intein Mediated Purification with an Affinity Chitin-binding ... engineered protein splicing elements (termed inteins) to ... column (1-4) (Figures 1 and 2). This ... systems by its ability to separate a ...
... Analysis Note: The kit contains all ... convenient determination of NADPH-cytochrome c reductase activity ... purified microsomes [endoplastic reticulum (ER)]. It has ... tissues such as liver, kidney, brain, spleen, ...
... provides the reagents to efficiently differentiate ... myotubes. By efficiently promoting myogenic differentiation, ... in studies examining myogenesis, transcription factor ... muscle cell replacement therapy. By providing ...
... CHEMICON's Cell Transformation Detection Assay is an ... is considered the most stringent assay for ... this assay, cells (pre-treated with carcinogens or ... in soft agar medium for 21-28 days. ...
Biology Products: