Navigation Links
Breath study brings roadside drug testing closer
Date:4/25/2013

A group of researchers from Sweden have provided further evidence that illegal drugs can be detected in the breath, opening up the possibility of a roadside breathalyzer test to detect substances such as cocaine, amphetamines and cannabis.

Using a simple, commercially available breath sampler, the researchers have successfully identified a range of 12 substances in the breath of 40 patients recruited from a drug emergency clinic in Stockholm.

Their findings have been published today, 26 April, in IOP Publishing's Journal of Breath Research.

Blood, urine and saliva are the most popular methods for detecting illegal drugs and are already used by law enforcement in a number of countries; however, exhaled breath is seen as a promising alternative as it's easier to collect, non-invasive, less prone to adulteration and advantageous when location becomes an obstacle, such as at the roadside.

Exhaled breath contains very small particles that carry non-volatile substances from the airway lining fluid. Any compound that has been inhaled, or is present in the blood, may contaminate this fluid and pass into the breath when the airways open. The compounds will then be exhaled and can subsequently be detected.

In this study, researchers from the Karolinska Institute in Stockholm collected breath, blood plasma and urine samples from 47 patients (38 males, 9 females) who had taken drugs in the previous 24 hours and were recovering at a drug addiction emergency clinic.

Interviews were also undertaken with each patient to assess their history of drug use.

The breath samples were taken using a commercially available sampling device SensAbues and then analysed using liquid chromatography and mass spectrometry.

The portable sampling device consists of a mouth piece and a micro-particle filter. When a patient breathes into the mouth piece, saliva and larger particles are separated from the micro-particles that need to be measured.

The micro-particles are able to pass through and deposit onto a filter, which can then be sealed and stored ready for analysis. Breath samples were analysed for twelve substances.

Alprazolam and benzoylecgonine were detected in exhaled breath for the first time, whereas for methadone, amphetamine, methamphetamine, cocaine, morphine, 6-acetylmorphine, tetrahydrocannabinol, buprenorphine, diazepam and oxazepam, the results confirmed previous observations.

"Considering the samples were taken 24 hours after the intake of drugs, we were surprised to find that there was still high detectability for most drugs," said lead author of the study Professor Olof Beck.

"In cases of suspected driving under the influence of drugs, blood samples could be taken in parallel with breath when back at a police station. Future studies should therefore test the correlation between blood concentration of drugs of abuse and the concentrations in exhaled breath."


'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Related biology technology :

1. Medzilla.com Special Report: Unemployed Can Breathe a Little Freer After Supreme Court's Affordable Care Act Ruling
2. Breathe Better With Clarity Allergy Center
3. Next Breath Receives ISO/IEC 17025:2005 Accreditation from the American Association for Laboratory Accreditation
4. Researchers look to breath to identify stress
5. Positive Clinical Study Results for BSPs HyperQ Technology
6. 15-Minute Data From Phase 3 Study of Avanafil Featured as a Late Breaking Abstract at SMSNA Annual Meeting
7. DermTechs Non-invasive Melanoma Detection Assay Poised to Enter Clinical Validation Study
8. Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver
9. Clionsky Neuro Systems (CNS-Neuro) Announces Publication of Study Finding Elderly Patients Unable to Recognize Their Memory Loss
10. Convergence Pharmaceuticals Initiates Phase I Multiple Ascending Dose Study for CNV2197944
11. AtheroNova Inc. Preclinical Study Demonstrates 95% Reduction in Arterial Plaque Formation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... 26, 2016 , ... After several promising treatments in Panama ... City of Knowledge in Panama, a 6 year-old Duchenne’s muscular dystrophy patient received ... year following FDA approval of a second application for a single patient, investigational ...
(Date:5/25/2016)... Portland, Oregon (PRWEB) , ... May 25, 2016 ... ... Base Set features a variety of fracture-specific plating options designed to address fractures ... provide industry-leading fracture fixation solutions. , The Acumed Ankle Plating System 3 is ...
(Date:5/25/2016)... ... May 25, 2016 , ... Lady had been battling arthritis since ... ligament in her left knee. Lady’s owner Hannah sought the help of Dr Jeff ... surgeon, to repair her cruciate ligament and help with the pain of Lady’s arthritis. ...
(Date:5/24/2016)... ... May 24, 2016 , ... ... identity. The new Media Cybernetics corporate branding reflects a results-driven revitalization for a ... image analysis. The re-branding components include a crisp, refreshed logo and a new ...
Breaking Biology Technology:
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
Breaking Biology News(10 mins):