Navigation Links
Brandeis lab's artificial cilia spur new thinking in nanotechnology
Date:7/29/2011

Cilia, tiny hair-like structures that perform feats such as clearing microscopic debris from the lungs and determining the correct location of organs during development, move in mysterious ways. Their beating motions are synchronized to produce metachronal waves, similar in appearance to "the wave" created in large arenas when audience members use their hands to produce a pattern of movement around the entire stadium.

Due to the importance of ciliary functions for health, there is great interest in understanding the mechanism that controls the cilias' beating patterns. But learning exactly how cilia movement is coordinated has been challenging.

That may be beginning to change as a result of the creation, by a team of Brandeis researchers, of artificial cilia-like structures that dramatically offers a new approach for cilia study.

In a recent paper published in the journal Science, Associate Professor of Physics Zvonimir Dogic and colleagues present the first example of a simple microscopic system that self-organizes to produce cilia-like beating patterns.

"We've shown that there is a new approach toward studying the beating," says Dogic. "Instead of deconstructing the fully functioning structure, we can start building complexity from the ground up."

The complexity of these structures presents a major challenge as each cilium contains more than 600 different proteins. For this reason, most previous studies of cilia have employed a top-down approach, attempting to study the beating mechanism by deconstructing the fully functioning structures through the systematic elimination of individual components.

The interdisciplinary team consisted of physics graduate student Timothy Sanchez and biochemistry graduate student David Welch who worked with biologist Daniela Nicastro and Dogic. Their experimental system was comprised of three main components: microtubule filaments tiny hollow cylinders found in both
'/>"/>

Contact: Susan Chaityn Lebovits
lebovits@brandeis.edu
781-736-4027
Brandeis University
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Hooper Holmes Heritage Labs Division Launches New Home Diabetes Test
2. GeoVax Labs, Inc. Announces Six Month Financial Results and Provides Operational Update
3. Interleukin Genetics Licenses its PST(R) Genetic Test to OralDNA Labs
4. Association of Clinical Research Organizations (ACRO) Welcomes Clinilabs and RPS as New Members
5. Oridion Expands its OEM Partnerships - New Agreement with Spacelabs Healthcare
6. Preliminary Report of American Biotech Labs HIV Study Featured in Inaugural Issue of Journal of the Science of Healing Outcomes
7. Concentric Named Professional Agency of Record for Discovery Labs SURFAXIN(R)
8. DFB Sells Coria Labs to Valeant Pharmaceuticals
9. GeoVax Labs, Inc. Information To Be Available Through Standard & Poors Market Access Program
10. Nikon Instruments Appoints LABSCO its Clinical Distributor in Six States
11. GlaxoSmithKline to Acquire Genelabs Technologies to Increase Focus on Novel Small Molecule Therapies for Hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... The very idea of fibers made of carbon nanotubes is ... literally. , The single-walled carbon nanotubes in new fibers created ... through a process designed by chemist Angel Mart and his ... reported its results this month in the journal ACS ... they,re drawn together into a fiber. , Left to their ...
(Date:9/15/2014)... MORRISVILLE, NC (PRWEB) September 15, 2014 ... newly developed deep imaging OCT system for the optical ... , The EnvisuTM S4410 SDOCT for Contact ... measurements for standard and high complexity contact lens, IOL ... allows imaging of a complete contact lens immersed in ...
(Date:9/15/2014)... BOISE, Idaho , Sept. 15, 2014  iVinci ... and only comprehensive Patient Revenue Management system, branded as ... The company also announced the launch of a new ... Portal that provides an easy and convenient way for ... plans for balances owed by them and their families. ...
(Date:9/15/2014)... The chemistry, taste, and health effects of tea can vary ... the nonprofit American Botanical Council (ABC). Recent research by ... on the phytochemical compounds in tea ( Camellia sinensis ) ... in the Yunnan province of southwestern ... future of medicinal botanicals. Dr. Ahmed,s report on ...
Breaking Biology Technology:Rice rolls 'neat' nanotube fibers 2Rice rolls 'neat' nanotube fibers 3Bioptigen Introduces Deep Imaging OCT System for Contact Lens Metrology 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3Tea Taste and Quality Affected by Climate Change 2Tea Taste and Quality Affected by Climate Change 3Tea Taste and Quality Affected by Climate Change 4
... Switzerland, Jan. 5, 2012   Selexis SA ... Ph.D., will present at the Biotech Showcase 2012 Conference ... Conference in San Francisco, CA. Dr. Fisch ... Growth Investment" to prospective investors and corporate partners on ...
... Calif., Jan. 5, 2012  AtheroNova, (OTCQB: AHRO) ("AtheroNova"), a biotech ... regress atherosclerotic plaque, announced today that it has appointed Johan ... of Directors of the Company effective January 3, 2012. Mr. ... Audit and Medical Committees of the Board. ...
... 2012 CMC Biologics, a leading biopharmaceutical contract ... No. US 2,171,034 B1 covering a method for ... culture bioreactors. The invention is designed to optimize ... fermentation process, wherein the bioreactor (fermenter) has an ...
Cached Biology Technology:Selexis SA to Present at Biotech Showcase 2012 2AtheroNova Announces a New Board Member 2AtheroNova Announces a New Board Member 3CMC Biologics Strengthens its Innovative Biomanufacturing Technology Portfolio in Continuous Perfusion Systems 2
(Date:9/16/2014)... available in Spanish . ... study published in the Journal of Cell Biology ... for proper cell division , At this very moment thousands ... the mechanism by which the body repairs damaged tissues and ... complex process known as "mitosis", during which the cell duplicates ...
(Date:9/16/2014)... PALM BEACH GARDENS, Fla. , Sept. 16, ... provider of biometric identity management solutions, announced today ... handheld solution designed to authenticate the identity of ... The Android-based Verifier Sentry rapidly reads ... the credential holder,s ID by matching the biometric ...
(Date:9/15/2014)... populations may continue to drop in French Guiana, despite ... National de la Chasse et de la Faune Sauvage ... data retrieved from camera traps in the Nouragues National ... data to current harvest rates in the region., "In ... Guiana," said Matthias Tobler, a scientist with the San ...
Breaking Biology News(10 mins):Unraveling cell division 2Unraveling cell division 3Cross Match Launches New Identity Management Handheld Solution 2
... underlying brain skills needed to think, remember and learn are ... fact of life for most older Americans. ... critically important for lessening declines in mental performance as people ... efforts aimed at preventing or delaying cognitive decline, dietary modifications ...
... on biomarkers of cardiovascular disease: implications for heart-healthy diets," ... , examined 26 clinical studies and two meta-analyses to ... Of the probiotics examined, L. reuteri NCIMB 30242 ... (TLC) dietary requirements by: , Significantly ...
... , Fires in and around Snowy River National Park in ... (MODIS) aboard the Aqua satellite on February 06, 2014. Actively ... red. Hot, dry, windy conditions in Victoria have been ... territory. The fires in this image are located in ...
Cached Biology News:Nutritional supplement improves cognitive performance in older adults, study finds 2Nutritional supplement improves cognitive performance in older adults, study finds 3Heart health through gut health 2
Request Info...
Kit containing positive control DNA all parts of the HIV-1 genome, HIV-1 negative control DNA, Primers SK38, SK39, SK19...
Contains 0.2 g/L EDTA4Na in phosphate-buffered saline....
Immunochemistry 1 & 2...
Biology Products: