Navigation Links
BioNano Genomics Announces the Purchase of the Irys System by BGI
Date:7/31/2014

SAN DIEGO and SHENZHEN, China, July 31, 2014 /PRNewswire/ -- BioNano Genomics announced today the purchase of an Irys™System by BGI, the world's largest genomics organization. BGI selected BioNano's platform to enable comprehensive exploration of human structural variation (SV) and to provide vastly improved assemblies for various organisms of interest, including those where no reference exists. In addition, BioNano and BGI will partner together to develop new methods for multiplexing on the Irys System, enabling significantly higher sample throughput to be performed with fewer reagents, a capability that will be particularly useful for large-scale studies.

"We have been collaborating with BioNano Genomics on human samples of Asian descent and are impressed by the capabilities of the Irys technology to efficiently detect hundreds of large (>1kb) complex genomic structural variations," said Xun Xu, deputy director at BGI. "As part of our efforts to further elucidate genome biology, BGI needed a solution to investigate large structural variation that is not easily accessible through sequencing, DNA arrays or other technologies. Now it is feasible to do population-scale, comprehensive large structural variation discovery on a single technology platform using BioNano's Irys System." 

The Irys System, which is based on the high-throughput chip, IrysChip™ V2, is an ideal SV discovery tool because it can detect all types of SVs in a single run, enabling rapid and accurate de novo genome assembly and genome completion. Genome maps built with the Irys System reveal the biologically and clinically significant order and orientation of functionally relevant components of complex genomes, including genes, promoters, regulatory elements, the length and location of long areas of repeats as well as viral integration sites across the entire genome that are often implicated in the cause of complex diseases such as cancer. Assembling such a comprehensive view of a genome has previously been a major hurdle because information about large repetitive elements and structural variations are lost with next generation sequencing (NGS) methods. 

"We are very excited to add this platform to our portfolio of cutting edge technologies and service solutions as we seek to continue providing better and more comprehensive genomic services for our customers worldwide," said Yingrui Li, CEO of BGI Tech, a subsidiary of BGI that provides scientific and technological service solutions to biomedical, agricultural, and environmental customers globally. 

"With the Irys System, we enable researchers to rapidly identify accurate structural information over long-range distances with virtually no alteration to the native genomic samples," said Han Cao, Ph.D., founder and chief scientific officer of BioNano Genomics. "As a versatile and sensitive single molecule imaging platform, Irys enables the de novo assembly of genomes containing complex, highly variable regions, as well as the accurate detection of all types of structural variation, both balanced and imbalanced, within complex heterogeneous samples."

BGI is the latest to adopt the Irys System. Others include the Garvan Institute, who are using their Irys for human and cancer genomics, UC San Francisco, for genomic investigations of a range of species from viruses to humans, and Kansas State University, for the i5k Insect and other Arthropod Genome Sequencing Initiative.

About Irys

Irys makes it possible to routinely and accurately detect genomic structural variation and to finish genome assemblies. The fully automated Irys benchtop instrument uses the IrysChip to uncoil and confine long DNA molecules in proprietary Nanochannel Arrays™ where they are uniformly linearized in a highly parallel display for high-resolution, single-molecule imaging. Irys does not employ DNA fragmentation or amplification, which are typical with next-generation sequencing. The result is sequence information over extremely long "reads" ranging from hundreds of kilobases to a megabase, where the sample's valuable structural information is preserved. Irys makes it possible for researchers to directly observe structural variants including replications, deletions, translocations and inversions.

About BioNano Genomics

Headquartered in San Diego, BioNano Genomics is delivering an altogether better way of gaining a fully informed understanding of genomes. The Company's platform provides researchers and clinicians the most comprehensive, organized and actionable picture of a genome with unprecedented insights into how the individual components of genomes are ordered, arranged, and interact with each other. BioNano Genomics works with institutions in life science, translational research, molecular diagnostics and personalized medicine. The Company is supported by private investors and grant funding from genomics programs at federal agencies, including the NIH and NIST-ATP.

www.BioNanoGenomics.com

About BGI

BGI was founded in 1999 with the mission of being a premier scientific partner to the global research community. The goal of BGI is to make leading-edge genomic science highly accessible through its investment in infrastructure that leverages the best available technology, economies of scale, and expert bioinformatics resources. BGI, which includes both private non-profit genomic research institutes and sequencing application commercial units, and its affiliates, BGI Americas, and BGI Europe, have established partnerships and collaborations with leading academic and government research institutions as well as global biotechnology and pharmaceutical companies, supporting a variety of disease, agricultural, environmental, and related applications. BGI has achieved a proven track record of excellence, delivering results with high efficiency and accuracy for innovative, high-profile research which has generated over 600 publications in top-tier scientific journals. For more information about BGI and BGI Tech, please visit www.genomics.cn and www.bgitechsolutions.com.


'/>"/>
SOURCE BioNano Genomics
Copyright©2014 PR Newswire.
All rights reserved

Related biology technology :

1. BioNano Genomics Signs Two New Distributors For The Asia-Pacific Region And Announces First Irys System Placement In Korea To ChunLab
2. BioNano Genomics Announces the Adoption of Irys System by the Garvan Institute of Medical Research
3. BioNano Genomics Announces The Purchase Of The Irys System By The Chinese Academy Of Sciences And Tel Aviv University
4. BIT Group Partners with BioNano Genomics to Produce Revolutionary Genomics Platform
5. BioNano Genomics lanza Irys en Europa en ESHG 2013
6. BioNano Genomics führt auf ESHG 2013 Irys in Europa ein
7. BioNano Genomics Launches Irys In Europe At ESHG 2013
8. Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific
9. Cypher Genomics Announces the Appointment of Adam Simpson as President and COO to Advance Transformative Genome Interpretation Technology
10. BGI Tech lancerer Human Whole Exome-sekvenseringstjeneste på Complete Genomics avancerede platform
11. BGI Tech lancia un servizio di sequenziamento dellintero esoma umano sulla piattaforma avanzata di Complete Genomics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... DuPont Pioneer and recently ... have entered into a multiyear collaboration to identify and characterize novel CRISPR-Cas nucleases. ... for gene editing across all applications. , Under the terms of the agreement, ...
(Date:10/12/2017)... ... 12, 2017 , ... AMRI, a global contract research, development ... patient outcomes and quality of life, will now be offering its impurity solutions ... new regulatory requirements for all new drug products, including the finalization of ICH ...
(Date:10/11/2017)... CA (PRWEB) , ... October 11, 2017 , ... ... upregulate any gene in its endogenous context, enabling overexpression experiments and avoiding the ... system with small RNA guides is transformative for performing systematic gain-of-function studies. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... today it will be hosting a Webinar titled, “Pathology is going digital. Is ... , on digital pathology adoption best practices and how Proscia improves lab economics ...
Breaking Biology Technology:
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:3/30/2017)... , March 30, 2017  On April 6-7, ... Hack the Genome hackathon at Microsoft,s headquarters ... two-day competition will focus on developing health and wellness ... Hack the Genome is the first ... tremendous. The world,s largest companies in the genomics, tech ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health ... and Management Systems Society (HIMSS) Analytics for achieving ... Adoption Model sm . In addition, CHS previously ... U.S. hospitals using an electronic medical record (EMR). ... its high level of EMR usage in an ...
Breaking Biology News(10 mins):