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Bacteria toxic to wound-treating maggots
Date:2/4/2010

cteria, the maggots were much better at surviving and potentially cleansing the wounds. Signalling between bacteria growing in biofilms is known to lead to the production of lethal toxins, without which the bacteria are more vulnerable to eradication."

Dr Andersen believes the research could benefit patients with persistent wounds. "MDT is generally very effective. It has been said that in a few cases MDT had failed, leaving the maggots dead in the lesion. We now think that this was probably due to the presence of P. aeruginosa in the wound," he said. "If we can find the specific bacterial mechanism that kills the maggots, we could target this when developing new treatments. For example, wounds infected with P. aeruginosa could be treated with an agent that interrupts bacterial signalling to ensure the success of maggot therapy and thereby wound healing."


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Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

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