Navigation Links
Bacteria toxic to wound-treating maggots
Date:2/4/2010

Bacteria that infect chronic wounds can be deadly to maggot 'biosurgeons' used to treat the lesions, show researchers writing in the journal Microbiology. The findings could lead to more effective treatment of wounds and the development of novel antibiotics.

Scientists from the Copenhagen Wound Healing Centre, Statens Serum Institut and the University of Copenhagen in Denmark showed that maggots applied to simulated wounds heavily infected with the bacterium Pseudomonas aeruginosa, were unable to treat the wound and were left dead after 20 hours.

Chronic wounds, such as leg ulcers, affect 1% of the Western population and are painful and difficult to treat. Use of maggots to disinfect wounds is an ancient practice that regained popularity in the early 1990s. Maggot Debridement Therapy (MDT) is now a standard procedure at wound care centres all over the world, in which sterile larvae from the green bottle fly Lucilia sericata are applied to the wound either directly or contained within a sealed nylon bag. The maggots gently ingest necrotic (dead) tissue and kill ingested bacteria in the gut. In addition, the maggots secrete antimicrobial compounds into the wound, help reduce inflammation and promote wound healing. The actual biological mechanisms responsible for the process are still largely a mystery.

P. aeruginosa is an opportunistic bacterium responsible for many hospital-acquired infections. It is often associated with chronic wounds in which the bacteria clump together to form biofilms. By effectively talking to each other via a well-studied communication system called quorum sensing (QS), bacteria in biofilms are known to be more successful at avoiding destruction by the host immune system as well as antibiotics.

Dr Anders Schou Andersen, who led the research, explained that QS was also the key to P. aeruginosa's toxicity to maggots. "When we blocked the QS signalling pathways in the ba
'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Quick microchip test for dangerous antibiotic resistant bacteria
2. GlaxoSmithKline Awarded U.S. Department of Defense Contract to Pursue Novel Antibacterial Research Program
3. University of Leicester scientists discover technique to help friendly bacteria
4. ICBS acquires 30% interest in Bacteria Bank Ltd.
5. Verenium Explores Bacterial Genes Inside Termite Guts to Understand How Wood is Broken Down and Converted to Energy
6. NOLabs AB Achieves Break-Through in Fight Against MRSA-Bacteria
7. Free White Paper Available for Clinical Laboratory Managers: Effectively Isolating Anaerobic Bacteria
8. Venter Institute Scientists Create First Synthetic Bacterial Genome
9. Immune system protein starves staph bacteria
10. Study Confirms Anti-Infective ARIKACE(TM) Effectively Penetrates Mucus and Biofilm, and Kills Pseudomonas, a Bacteria Plaguing Cystic Fibrosis Patients
11. Rib-X Pharmaceuticals to Present at Cambridge Healthtech Institutes 2nd Annual Challenge of Antibacterial Development Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... Leading CEOs, CSOs, ... pain management space join prominent academics and key investors for Neuro Advance Boston, ... School in Boston. , Neuro Advance Boston focuses on the latest developments ...
(Date:9/1/2015)... ... September 01, 2015 , ... Research ... California Los Angeles, Boston University School of Medicine, Frederick National Laboratory for Cancer ... the world’s first multidisciplinary Open Access journal. , Christopher Ryan PhD, of ...
(Date:8/31/2015)... ... 31, 2015 , ... In recent years, biodegradable plastics have ... carbon footprints and compostability. These properties can help in limiting the degradation of ... of applications, the market for biodegradable plastics can be broadly segmented into packaging, ...
(Date:8/31/2015)... Research and Markets ( http://www.researchandmarkets.com/research/cbgl72/middle_east_and ) has ... Africa Biomedical Sensors Market - Growth, Trends & Forecasts ... The Middle East & Africa ... 2018 at a CAGR of 3.26% over the period ... sensors that are adaptable to the genetic formulation of ...
Breaking Biology Technology:Neuro Advance Boston Brings Together Leading Neuroscience Experts on October 14 at Harvard Medical School 2Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 2Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 2Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 4Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 5Middle East & Africa Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts to 2020 2
... foster drug delivery - , , ... Today, Roche Madison Inc. officially opened the doors ... biology labs at the University of Wisconsin ... global RNA Therapeutics group within Roche, the group,s ...
... Government and private insurers are placing unprecedented pressures ... products they develop, according to The 2009 Ernst & ... individuals are likely to increase demands to demonstrate value ... costs, a shrinking tax base, aging populations, and a ...
... and LOS ANGELES, April 23 /PRNewswire-Asia-FirstCall/ --, - Fourth Quarter ... Income was $0.9 Million and Diluted EPS of $.03, ... - 2008 Gross Profit Margin Improved 340 Basis Points to 20.1%, ... of, $0.13, - 2008 Cash ...
Cached Biology Technology:Roche Madison Moves to New Facility 2Roche Madison Moves to New Facility 3Failing to Demonstrate Value of Innovation is Top Risk Facing Life Sciences Sector, According to Ernst & Young 2Failing to Demonstrate Value of Innovation is Top Risk Facing Life Sciences Sector, According to Ernst & Young 3Failing to Demonstrate Value of Innovation is Top Risk Facing Life Sciences Sector, According to Ernst & Young 4China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 2China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 3China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 4China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 5China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 6China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 7China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 8China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 9China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 10China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results 11
(Date:8/20/2015)... Aug. 20, 2015 The wearable technology ... are active and healthy. However, wearable technology has ... environment to help improve diagnostic capabilities and therapeutic ... the Wearable Technologies Conference 2015 , where ... for wearables in healthcare.    "Over ...
(Date:8/18/2015)... Aug. 17, 2015 Research and Markets ... the "Global Biometric Authentication & Identification Market: ... & Forecast, 2015-2020" report to their offering. ... identification systems market is expected to grow at ... 2020 and generate over $25 billion (approximately) by ...
(Date:8/12/2015)... Calif. , Aug. 12, 2015  Synaptics ... of human interface solutions, today announced that four ... announced Match-in-Sensor solution, have officially been named FIDO ... As part of the certification, Synaptics, Natural ID™ ... 1.0 Universal Authentication Framework (UAF) standard and are ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
... in Nature Cell Biology , scientists from the ... Regenerative Medicine Institute (ARMI) have revealed new insights into ... In an early mammalian embryo, just 8-cells large, the ... something that would determine whether the embryo survived ...
... Colo., USA Locations studied for this month,s posting ... Llaima volcano, Chile; the Mississippi Fan (Gulf of Mexico); ... the Atlas Mountains of Morocco; the East Antarctic Ice ... Regab pockmark, offshore Africa; the Siberian Traps; the eastern ...
... significant signaling network in a tiny organism that,s big ... how a remarkably fast-growing organism conducts its metabolic business ... microbe Synechococcus , which turns sunlight into useful ... Pacific Northwest National Laboratory glimpsed key chemical events, known ...
Cached Biology News:Your first hug: How the early embryo changes shape 2Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 2Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 3Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 4Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 5Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 6Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 7Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 8Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 9Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 10Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 11Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 12Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 13Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 14Offshore pockmarks, Wax Lake Delta, Cabo de Gata, the Siberian Traps: Geology covers the world 15Scientists capture 'redox moments' in living cells 2Scientists capture 'redox moments' in living cells 3
... TNT Coupled Reticulocyte Lysate Systems(a,b,c,d) offer ... vitro translations: a single-tube, coupled transcription/translation ... simplify the process and reduce the ... translation results. Standard rabbit reticulocyte lysate ...
... ml per liter of urine will give a ... BMD dipstick. ,Certification: The Donors are of ... to be NEGATIVE for HbsAg, HCV, HIV-1 & ... FDA methods. THIS MATERIAL IS SOLD FOR IN-VITRO ...
... except that it uses a deep-UV deuterium bulb, ... comes with a shutter (controlled via a TTL ... The DH-2000 Deuterium Tungsten Halogen Light Source ... halogen light sources in a single optical path. ...
... is a dedicated cuff pump for small animal ... manual inflation and can be used for all ... and rat; from single up to multi-channel systems ... has adjustable cut-off pressure in 50 mmHg increments, ...
Biology Products: