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Avian Adenovirus Genotyping Diagnostic Service
Date:5/8/2009

it is possible to group together different Fowl Adenovirus strains in 5 (A-E) Genogroups based on their hexon L1 sequences. Inside each Genogroup it is possible to distinguish different clades that may be associated with individual serotypes. Pyrosequencing analysis of key variable regions allows the rapid determination of lack of association of any two analysed samples. Should samples display characteristics that indicate possible association with each other, the use of boot strapping analysis on extended genetic sequences allows the investigator to arrive at statistically significant conclusions regarding the genotype of a strain and its association with another strain. Thus the technology is ideally suited to determine if an adenovirus isolated from one flock is genetically the same (and hence a candidate for vertical transmission) as a virus isolated from its source supply flock.

Further details of this novel diagnostic technology are available directly from x-OvO Limited. www.x-ovo.com

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Read the full story at http://www.prweb.com/releases/2009/05/prweb2398834.htm.


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