Navigation Links
Asymmetrex Presents Adult Tissue Stem Cell Counting at the Alliance for Regenerative Medicine’s First Partnering Conference, May 22-23
Date:5/16/2017

On Tuesday, May 23 at 10:30 AM, James Sherley, Director of Asymmetrex, will have an ideal audience for introducing the advance in stem cell medicine that his company has recently achieved in collaboration with its partner, AlphaSTAR Corporation. Tuesday will be the second day of the Alliance for Regenerative Medicine’s first partnering conference, Cell & Gene Exchange 2017. In addition to his formal talk, Sherley will meet with interested companies in one-on-one partnering sessions to introduce them to the many advantages that Asymmetrex’s AlphaSTEM Test service offers.

Asymmetrex and AlphaSTAR partnered to develop the first method for specific counting of adult tissue stem cells. The AlphaSTEM Test is the result of the integration of Asymmetrex’s expertise in the unique cell production behavior of tissue stem cells and AlphaSTAR’s cutting-edge methods in computational simulation. By a proprietary analysis of simple cell growth data from cultures containing adult tissue stem cells, the AlphaSTEM Test technology can determine, with a high degree of precision, the number and behavior of tissue stem cells in complex cell preparations from many different types of human tissues.

For stem cell therapy companies, the AlphaSTEM Test offers the ability to determine stem cell dose for the first time. Currently, the only clinical test available for estimating whether treated patients have received sufficient stem cells is the CD34 marker for blood stem cells. However, because it does not give a specific blood stem cell dose, CD34 has poor sensitivity and specificity. The weak efficacy that CD34 does provide is limited primarily to blood stem cells. The AlphaSTEM Test offers the ability to determine specific dosing for stem cells from many different tissues.

Gene therapy and gene editing companies that genetically engineer blood stem cells – called hematopoietic stem cells (HSCs) – could also benefit from the AlphaSTEM Test service. HSCs are the targets for gene treatments, because they are the only blood cells that are naturally maintained in the body for the long periods required for stable genetic cures. Because human HSCs are rare cells even in the most enriched clinical preparations, their starting number and their remaining number, respectively before and after genetic engineering procedures, are important data for optimization of the engineering and ensuring that sufficient modified HSCs are available for effective treatment.

Though minor participants in the conference, Asymmetrex will also address pharmaceutical companies. Asymmetrex has established that the AlphaSTEM Test can be employed to identify stem cell-active agents. The test has been validated with known stem cell-toxic drugs and stem cell-activating compounds. The current main service focus for Pharma is stem cell-toxic drug candidates. Stem cell toxicity causes chronic organ failure, a property that generally means a failed drug. Twenty to 30% of all drugs fail in Phase II and Phase III clinical trials due to intolerable toxicity. About half of these failures are due to chronic organ failure, which costs the average large pharmaceutical company $100-300 million each year. Asymmetrex’s AlphaSTEM Test could identify many of these future failures much earlier, even before animal studies, giving a substantial savings to pharmaceutical companies in real dollars and patient safety. The impact would be even greater for drugs that did not manifest chronic organ failure until after they were in the marketplace.

Asymmetrex launched the AlphaSTEM Test contract service in September 2016. Thus far, adoption of the new technology has been measured. Asymmetrex’s presentation at Cell & Gene Exchange 2017 is part of the company’s mounting marketing campaign to increase awareness of the new technology in relevant fields. In addition to marketing to prospective clients, the company is discussing potential distribution partnerships with established contract research and contract medical organizations. Director Sherley is optimistic that “this is a technology that will become a must have for everyone and anyone working with adult tissue stem cells. If you are investigating them, treating with them, testing drugs with them, or supplying them, how could you pass up now knowing how many they are?”

About Asymmetrex

Asymmetrex, LLC is a Massachusetts life sciences company with a focus on developing technologies to advance stem cell medicine. Asymmetrex’s founder and director, James L. Sherley, M.D., Ph.D. is an internationally recognized expert on the unique properties of adult tissue stem cells. The company’s patent portfolio contains biotechnologies that solve the two main technical problems – production and quantification – that have stood in the way of successful commercialization of human adult tissue stem cells for regenerative medicine and drug development. In addition, the portfolio includes novel technologies for isolating cancer stem cells and producing induced pluripotent stem cells for disease research purposes. Currently, Asymmetrex’s focus is employing its technological advantages to develop and market facile methods for monitoring adult stem cell number and function in stem cell transplantation treatments and in pre-clinical assays for drug safety.

Read the full story at http://www.prweb.com/releases/2017/05/prweb14338986.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related biology technology :

1. At 6th Annual Clinical Trial Supply New England 2017 Conference in Boston Asymmetrex Introduces A First Specific Quality Control Test for Therapeutic Tissue Stem Cells
2. Asymmetrex’s Head Will Lead Discussion on Supplying Private Stem Cell Clinics at the 6th Annual Clinical Trial Supply New England 2017 Conference in Boston
3. Asymmetrex's AlphaSTEM Test Adult Tissue Stem Cell Counting Technology Established to Be a Leading Interest for Regenerative Medicine in 2016
4. Asymmetrex Director Shares Vision for Company and Private Stem Cell Treatment Clinics in Two Arena International Event Group Forums
5. Asymmetrex Presents Technologies to Accelerate Gene-Editing Therapeutics Progress
6. Asymmetrex Continues Efforts to Raise Awareness of the Importance of Tissue Stem Cell Counting for Advancing Gene-Editing Therapeutics
7. In a Scheduled March 22 RegMedNet Webinar, Asymmetrex Discusses the Strategy for Its AlphaSTEM Technology for Counting Adult Tissue Stem Cells
8. In Upcoming Webinar and Conferences, Asymmetrex Will Intensify Education on Counting Adult Tissue Stem Cells For Regenerative Medicine and Drug Development
9. Asymmetrex Supports UK RegMedNet with Sponsorship for Education on the Importance of Counting Adult Tissue Stem Cells in Regenerative Medicine Practice
10. With Disclosure of Recently Met Benchmarks for Its Adult Tissue Stem Cell Counting Technology, Asymmetrex Targets Applications to Enable Gene-Editing Therapies
11. Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2017)... ... May 19, 2017 , ... The University ... researchers with technologies ripe for commercialization, and who are affiliated with the 21 ... to submit proposals. QED, now in its tenth round, is the first multi-institutional ...
(Date:5/18/2017)... ... May 18, 2017 , ... Lajollacooks4u has added another ... a two-hour team-building package designed for groups of 10-30 people. Guests can ... include items, such as Blackened Shrimp with Edamame Salad, Pizza Rolls with Pepperoni ...
(Date:5/18/2017)... ... May 17, 2017 , ... NDA Partners Chairman Carl Peck, ... of Eurofins Advantar Laboratories and President of Pharmaceutical Development Business Unit of Cardinal Health, ... Eurofins and Cardinal Health, he was former Chief Operating Officer at Anaborex, Senior VP ...
(Date:5/18/2017)... ... May 17, 2017 , ... ... medical device compliance and commercialization, has just released version 9.0 of the Cognition ... this latest version of Cockpit,” says David Cronin, CEO of Cognition. “We’re thrilled ...
Breaking Biology Technology:
(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/17/2017)... 17, 2017 NXT-ID, Inc. (NASDAQ: NXTD ... filing of its 2016 Annual Report on Form 10-K on Thursday ... ... available in the Investor Relations section of the Company,s website at ... website at http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... 11, 2017 Research and Markets has announced ... report to their offering. ... global eye tracking market to grow at a CAGR of 30.37% ... Tracking Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
Breaking Biology News(10 mins):