Navigation Links
Assembling cells into artificial 3-D microtissues, including a tiny gland
Date:3/5/2009

Berkeley -- As synthetic biologists cram more and more genes into microbes to make genetically engineered organisms produce ever more complex drugs and chemicals, two University of California chemists have gone a step further.

They have assembled different types of genetically engineered cells into synthetic microtissues that can perform functions such as secreting and responding to hormones, promising more complex biological capabilities than a single cell alone could produce.

"This is like another level of hierarchical complexity for synthetic biology," said coauthor Carolyn Bertozzi, UC Berkeley professor of chemistry and of molecular and cell biology and director of the Molecular Foundry at Lawrence Berkeley National Laboratory. "People used to think of the cell as the fundamental unit. But the truth is that there are collections of cells that can do things that no individual cell could ever be programmed to do. We are trying to achieve the properties of organs now, though not yet organisms."

While the synthetic tissues today comprise only a handful of cells, they could eventually be scaled up to make artificial organs that could help scientists understand the interactions among cells in the body and might some day substitute for human organs.

"We are really taking this into the third dimension now, which for me is particularly exciting," said first author Zev J. Gartner, a former UC Berkeley post-doctoral fellow who recently joined the UC San Francisco faculty as an assistant professor of pharmaceutical chemistry. "We are not simply linking cells together, we are linking them together in 3-D arrangements, which introduces a whole new level of cellular behavior which you would never see in 2-D environments."

Gartner and Bertozzi, the T.Z. and Irmgard Chu Distinguished Professor at UC Berkeley and a Howard Hughes Medical Institute investigator, report on their assembly of three-dimensional microtissues this week i
'/>"/>

Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Self-assembling polymer arrays improve data storage potential
2. Novocell Announces Discovery Linking Key Cancer Cell Signaling Pathways With Proliferation and Self-Renewal of Human Embryonic Stem Cells
3. Reovirus Infection of Melanoma Cells Generates Anti-Tumour Immunity
4. Scientists synthesize memory in yeast cells
5. BioLife Solutions CryoStor(TM) Adopted by Tissue Regeneration Therapeutics for Preservation Protocol for New, Non-Embryonic Source of Stem Cells
6. Patent Office Rules in Neuralstems Favor in Dispute with StemCells, Inc.
7. NIH Announces Advanced Cell Technologys Single Cell Embryo Biopsy Technique as a Means to Derive Embryonic Stem Cells to be Considered for Federal Funding
8. Scientists synthesize memory in yeast cells
9. Breakthrough research identifies how cells from pigs may cure diabetes
10. Patent on Technology for the Delivery of Stem Cells to the Human Heart Issued to CellCyte Genetics Corp. of Washington
11. STEM CELLS Journal Names Co-Editors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Assembling cells into artificial 3-D microtissues, including a tiny gland
(Date:3/27/2015)... Earlier this year, the Capillus272Pro™ received FDA ... adult men and women with androgenic alopecia (AGA) having ... IIa-V and Fitzpatrick Classification of Skin phototypes I-IV. ... and under-deliver, FDA Clearance underscores the safety and efficacy ... than 80 million men and women who suffer with ...
(Date:3/27/2015)... NEW YORK , March 27, 2015 /PRNewswire/ ... leader in liquid photopurification, announced today that the ... approval for the continued trading of SurePure ("SURP") ... execution venture marketplace for entrepreneurial and development stage ... Markets Group introduced standards and eligibility requirements designed ...
(Date:3/27/2015)... 2015  CASI Pharmaceuticals, Inc. (Nasdaq: CASI ), ... commercialization of innovative therapeutics addressing cancer and other unmet ... focus on China , today reported ... December 31, 2014.  The Company reported ... share, for the three months ended December 31, 2014.  ...
(Date:3/26/2015)... March 26, 2015 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" ... after dealing with certain matters, including the appointment of ... on March 26, 2015 (the "Meeting") was adjourned, as ... 2015 at 11:00 a.m. ( Toronto ... changed from that previous disclosed. The Meeting will reconvene ...
Breaking Biology Technology:Dr. Robert Leonard Applauds FDA Clearance of Capillus272Pro™ Hair Loss Laser Cap 2SurePure Completes Verification and Approved for Trading on the OTCQB Marketplace 2CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 2CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 3CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 4CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 5CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 6SQI Diagnostics Inc. Announces Adjournment of Meeting 2
... announced today that The Valley Hospital , a ... Ridgewood, N.J., has successfully implemented API's Payrollmation time and ... ,Payrollmation automates time and attendance data collection and streamlines ... improve employee morale and help the organization to control ...
... The Medical College of Wisconsin has implemented IBM ... computing infrastructure support system for proteomics research. IBM announced last ... based on Power Architecture will begin shipping in volume ... customer site to test the Sequest application on the JS20 ...
... future workforce have recently been issued by the Hudson ... tanks on economic, political and social issues. Both reports ... about to change dramatically as a result of global ... momentum. The result will be a vastly different corporate ...
Cached Biology Technology:Valley Hospital implements API's solution for 3,500 employees 2Medical College of Wisconsin enhances research with IBM Blade server 2Are you ready to play the new talent management game? 2Are you ready to play the new talent management game? 3
(Date:3/23/2015)... March 23, 2015   HOYOS Labs , a ... today announced that the Company will demonstrate multiple biometrics-based ... and consumers at Connect:ID on March 23 through 25, ... Labs will highlight the IEEE Biometric Open Protocol Standard; ... and enterprise access control system. BOPS was invented by ...
(Date:3/20/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market, announces its biometric payment technology, ... featured in 2015 "I Want That" International CES Special, ... the DIY Network.   DIY,s "I Want ... site of the 2015 International CES for a firsthand ...
(Date:3/17/2015)... , March 17, 2015 Emotient, ... analytics software, today announced general availability of ... service for the analysis of facial expressions. The ... advertising, media content, products and services. It delivers ... engagement and sentiment - as derived from facial ...
Breaking Biology News(10 mins):HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
... Wikipedia entry for the hummingbird explains that the bird,s ... that helps the bird hover. But after conducting experiments ... California, Riverside propose that the hovering hummingbird instead produces two ... that help generate the aerodynamic forces required for the ...
... The University of Nottingham has been used in a ... of a fully functioning fetal heart. The abdominal ... University,s Department of Electrical and Electronic Engineering and on ... University spin-out company Monica Healthcare Ltd, has been used ...
... viruses, bacteria, worms and all other parasites need to ... of infectious diseases under climate change, according to new ... can identify the prospects for nearly any disease-causing parasite ... known about the organism. Their method calculates how the ...
Cached Biology News:2 vortex trails with 1 stroke 22 vortex trails with 1 stroke 3Nottingham technology in heart development breakthrough 2Nottingham technology in heart development breakthrough 3Nottingham technology in heart development breakthrough 4March of the pathogens: Parasite metabolism can foretell disease ranges under climate change 2March of the pathogens: Parasite metabolism can foretell disease ranges under climate change 3March of the pathogens: Parasite metabolism can foretell disease ranges under climate change 4
Kinase Buffer can be used to assay protein kinase activity...
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
...
Biology Products: